Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency

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Mediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency is …
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P819ADS bibcode2015PLoSO..1040192L
P356DOI10.1371/JOURNAL.PONE.0140192
P932PMC publication ID4596692
P698PubMed publication ID26445504
P5875ResearchGate publication ID282796260

P50authorJames F. GusellaQ1602688
Roberta L BeauchampQ125306032
Konrad HochedlingerQ40635003
P2093author name stringLin Li
Vijaya Ramesh
Marianne F James
Yuh-Shin Chang
Ryan M Walsh
Vilas Wagh
P2860cites workFormation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4Q22008002
Magicin associates with the Src-family kinases and is phosphorylated upon CD3 stimulationQ24299345
Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2Q24306359
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancerQ24616117
Mediator and cohesin connect gene expression and chromatin architectureQ24632695
The Mediator complex: a master coordinator of transcription and cell lineage developmentQ26859539
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cellsQ28176663
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activityQ28294122
Requirement of FGF-4 for postimplantation mouse developmentQ28304838
Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocystQ28506141
Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in miceQ28507179
Multipotent cell lineages in early mouse development depend on SOX2 functionQ28513175
Mediator subunit MED28 (Magicin) is a repressor of smooth muscle cell differentiationQ28594136
Master transcription factors and mediator establish super-enhancers at key cell identity genesQ29618062
Placental development: lessons from mouse mutantsQ29618167
Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cellsQ29618298
Nanog is required for primitive endoderm formation through a non-cell autonomous mechanism.Q33569702
Elevated MED28 expression predicts poor outcome in women with breast cancerQ33618514
The role of FGF/Erk signaling in pluripotent cellsQ34140525
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomasQ34210977
Unraveling framework of the ancestral Mediator complex in human diseasesQ34222553
The Hippo pathway member Nf2 is required for inner cell mass specificationQ34352625
A recurrent mutation in MED12 leading to R961W causes Opitz-Kaveggia syndromeQ34576763
Function and regulation of the Mediator complexQ34904976
MED29, a component of the mediator complex, possesses both oncogenic and tumor suppressive characteristics in pancreatic cancerQ35054391
Dynamic GATA6 expression in primitive endoderm formation and maturation in early mouse embryogenesisQ37337387
A reprogrammable mouse strain from gene-targeted embryonic stem cellsQ37704793
The Mediator complex and transcription elongationQ38043907
Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFRQ39961289
Cdk8 is essential for preimplantation mouse developmentQ40109457
Targeted inhibition of EG-1 blocks breast tumor growthQ40120024
Expression pattern of the novel gene EG-1 in cancerQ40552162
Induced pluripotent stem cell generation using a single lentiviral stem cell cassetteQ40721564
Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogrammingQ41833143
Missense mutations and gene interruption in PROSIT240, a novel TRAP240-like gene, in patients with congenital heart defect (transposition of the great arteries).Q41921707
MED23 mutation links intellectual disability to dysregulation of immediate early gene expressionQ48932486
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectpluripotencyQ1894941
P304page(s)e0140192
P577publication date2015-10-07
P1433published inPLOS OneQ564954
P1476titleMediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency
P478volume10