scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Kathleen W Kinnally | |
Pablo M Peixoto | |||
Laurent M Dejean | |||
P2860 | cites work | Bcl-2 family interaction with the mitochondrial morphogenesis machinery | Q24293601 |
Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis | Q24307662 | ||
A novel X-linked gene, DDP, shows mutations in families with deafness (DFN-1), dystonia, mental deficiency and blindness | Q24311730 | ||
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members | Q24337108 | ||
Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel | Q24523479 | ||
Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis | Q24533270 | ||
Microsecond time-scale discrimination among polycytidylic acid, polyadenylic acid, and polyuridylic acid as homopolymers or as segments within single RNA molecules | Q24537315 | ||
A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast | Q24685400 | ||
Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles | Q27651854 | ||
Structure of the human voltage-dependent anion channel | Q27652383 | ||
The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating | Q27652797 | ||
The Tim54p-Tim22p complex mediates insertion of proteins into the mitochondrial inner membrane | Q27931625 | ||
Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria | Q27932754 | ||
Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22. | Q27933337 | ||
Tim22, the essential core of the mitochondrial protein insertion complex, forms a voltage-activated and signal-gated channel | Q27935135 | ||
Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor | Q27935671 | ||
Role of Tim21 in mitochondrial translocation contact sites | Q27936374 | ||
Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. | Q27936577 | ||
Cyclosporin inhibits mitochondrial calcium efflux in isolated adult rat ventricular cardiomyocytes | Q28187564 | ||
The Ca2+-induced membrane transition in mitochondria. III. Transitional Ca2+ release | Q28211160 | ||
Mitochondrial permeability transition in acute neurodegeneration | Q28218571 | ||
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore | Q28241418 | ||
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death | Q28242641 | ||
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death | Q28242653 | ||
Complexes between porin, hexokinase, mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication for regulation of permeability transition by the kinases | Q28261309 | ||
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death | Q28297152 | ||
The Ca2+-induced membrane transition in mitochondria. I. The protective mechanisms | Q28305411 | ||
The Ca2+-induced membrane transition in mitochondria. II. Nature of the Ca2+ trigger site | Q28306067 | ||
Control of mitochondrial apoptosis by the Bcl-2 family | Q37385623 | ||
Mitochondrial calcium function and dysfunction in the central nervous system | Q37418288 | ||
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease | Q37463481 | ||
Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. | Q37466088 | ||
MAC and Bcl-2 family proteins conspire in a deadly plot | Q37677213 | ||
Mitochondrial ryanodine receptors and other mitochondrial Ca2+ permeable channels | Q37680210 | ||
Signal transduction to the permeability transition pore. | Q37691823 | ||
VDAC, a multi-functional mitochondrial protein regulating cell life and death | Q37719811 | ||
Role of mitochondrial ion channels in cell death | Q37771917 | ||
Mitochondrial protein import: from proteomics to functional mechanisms | Q37781692 | ||
Mechanisms by which mitochondria transport calcium | Q37920440 | ||
Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis. | Q38268983 | ||
BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program | Q38269004 | ||
Phosphorothioate oligonucleotides block the VDAC channel | Q38302060 | ||
Calcium signaling and neurodegenerative diseases | Q39463322 | ||
The nuclear receptor interacting factor-3 transcriptional coregulator mediates rapid apoptosis in breast cancer cells through direct and bystander-mediated events | Q40169586 | ||
The Bcl-2 family protein inhibitor, ABT-737, has substantial antimyeloma activity and shows synergistic effect with dexamethasone and melphalan. | Q40178770 | ||
Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia. | Q40355180 | ||
Targeting apoptosis via chemical design: inhibition of bid-induced cell death by small organic molecules. | Q40523260 | ||
Some amphiphilic cations block the mitochondrial apoptosis-induced channel, MAC. | Q40545426 | ||
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release | Q40551652 | ||
The permeability transition pore signals apoptosis by directing Bax translocation and multimerization. | Q40741871 | ||
A peptide-sensitive channel of large conductance is localized on mitochondrial outer membrane | Q41138468 | ||
Characterization and function of the mitochondrial outer membrane peptide-sensitive channel | Q41456643 | ||
Perspectives on the mitochondrial multiple conductance channel | Q41456650 | ||
VDAC closure increases calcium ion flux | Q41816375 | ||
Mitochondrial channel activity studied by patch-clamping mitoplasts | Q42014495 | ||
Upregulation of Bcl2 inhibits apoptosis-driven BAX insertion but favors BAX relocalization in mitochondria | Q28507255 | ||
Bax inserts into the mitochondrial outer membrane by different mechanisms | Q28567499 | ||
In self-defence: hexokinase promotes voltage-dependent anion channel closure and prevents mitochondria-mediated apoptotic cell death | Q28576382 | ||
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia | Q28585666 | ||
Role of Bax and Bak in mitochondrial morphogenesis | Q28591724 | ||
VDAC2 inhibits BAK activation and mitochondrial apoptosis | Q28594000 | ||
Mitochondrial membrane permeabilization in cell death | Q29547425 | ||
An inhibitor of Bcl-2 family proteins induces regression of solid tumours | Q29547595 | ||
The mitochondrial permeability transition pore and its role in cell death | Q29614183 | ||
Mitochondrial respiratory-chain diseases | Q29614474 | ||
Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases | Q29615646 | ||
Importing mitochondrial proteins: machineries and mechanisms | Q29616477 | ||
Translocation of proteins into mitochondria | Q29616478 | ||
Mitochondrial dynamics and apoptosis | Q29616570 | ||
Hunting interactomes of a membrane protein: obtaining the largest set of voltage-dependent anion channel-interacting protein epitopes. | Q30354657 | ||
Mitochondrial apoptosis is amplified through gap junctions | Q30491150 | ||
Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration | Q33346359 | ||
Mitochondrial ion channels as therapeutic targets | Q33857921 | ||
VDAC channels mediate and gate the flow of ATP: implications for the regulation of mitochondrial function | Q33915365 | ||
MitoP2, an integrated database on mitochondrial proteins in yeast and man | Q33974660 | ||
Properties of the mitochondrial peptide-sensitive cationic channel studied in planar bilayers and patches of giant liposomes | Q34091557 | ||
Mitochondrial shape changes: orchestrating cell pathophysiology. | Q34106103 | ||
Reversible and irreversible effects of basic peptides on the mitochondrial cationic channel | Q34115419 | ||
Old players in a new role: mitochondria-associated membranes, VDAC, and ryanodine receptors as contributors to calcium signal propagation from endoplasmic reticulum to the mitochondria | Q34172299 | ||
Transport of maltodextrins through maltoporin: a single-channel study | Q34177184 | ||
Comparison of the TIM and TOM Channel Activities of the Mitochondrial Protein Import Complexes | Q34181068 | ||
Therapeutic prospects for mitochondrial disease | Q34205124 | ||
Effects of cytochrome c on the mitochondrial apoptosis-induced channel MAC. | Q34312305 | ||
Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D. | Q34406704 | ||
Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia. | Q34458933 | ||
MCC and PSC, the putative protein import channels of mitochondria | Q34478958 | ||
Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt. | Q34487811 | ||
Is MAC the knife that cuts cytochrome c from mitochondria during apoptosis? | Q34522154 | ||
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction. | Q34562025 | ||
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels | Q34618715 | ||
Hydrogen peroxide sensing and signaling | Q34619087 | ||
Reconstitution in planar lipid bilayers of a voltage-dependent anion-selective channel obtained from paramecium mitochondria | Q42597073 | ||
The mitochondrial megachannel is the permeability transition pore | Q44175602 | ||
3,6-Dibromocarbazole Piperazine Derivatives of 2-Propanol as First Inhibitors of Cytochrome c Release via Bax Channel Modulation | Q44604105 | ||
Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia | Q46247309 | ||
Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2. | Q46499587 | ||
Methyl jasmonate binds to and detaches mitochondria-bound hexokinase | Q46647628 | ||
Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death | Q46839351 | ||
Fatal acute lymphoblastic leukemia in mice transgenic for B cell-restricted bcl-xL and c-myc. | Q47579113 | ||
The preprotein translocation channel of the outer membrane of mitochondria | Q47945539 | ||
Mitochondrial oxidative stress and cell death in astrocytes--requirement for stored Ca2+ and sustained opening of the permeability transition pore | Q48666655 | ||
Ca2+-dependent control of the permeability properties of the mitochondrial outer membrane and voltage-dependent anion-selective channel (VDAC). | Q50113362 | ||
Novel cobalt complex inhibitors of mitochondrial calcium uptake. | Q52536746 | ||
Novel murine B-cell lymphoma/leukemia model to study BCL2-driven oncogenesis. | Q53361793 | ||
Bid, but not Bax, regulates VDAC channels. | Q53849605 | ||
Mitochondria Are Excitable Organelles Capable of Generating and Conveying Electrical and Calcium Signals | Q53967833 | ||
The mitochondrial outer membrane channel, VDAC, is regulated by a synthetic polyanion. | Q54131150 | ||
Distribution of binding sequences for the mitochondrial import receptors Tom20, Tom22, and Tom70 in a presequence-carrying preprotein and a non-cleavable preprotein. | Q54263321 | ||
VavP-Bcl2 transgenic mice develop follicular lymphoma preceded by germinal center hyperplasia | Q56963014 | ||
The permeability transition and BCL-2 family proteins in apoptosis: co-conspirators or independent agents? | Q58454328 | ||
The isolated complex of the translocase of the outer membrane of mitochondria. Characterization of the cation-selective and voltage-gated preprotein-conducting pore | Q63005427 | ||
The outer mitochondrial membrane channel, VDAC, is modulated by a protein localized in the intermembrane space | Q63027298 | ||
Molecular design of the voltage-dependent, anion-selective channel in the mitochondrial outer membrane | Q63027302 | ||
NADH regulates the gating of VDAC, the mitochondrial outer membrane channel | Q63027309 | ||
The mitochondrial channel VDAC has a cation-selective open state | Q63027354 | ||
Single-particle approaches in the analysis of small 2D crystals of the mitochondrial channel VDAC | Q63027359 | ||
Modulation of the mitochondrial megachannel by divalent cations and protons | Q67895102 | ||
The role of pyridine dinucleotides in regulating the permeability of the mitochondrial outer membrane | Q71742645 | ||
ATP flux is controlled by a voltage-gated channel from the mitochondrial outer membrane | Q71763105 | ||
Solubilization and reconstitution of the mitochondrial peptide-sensitive channel | Q72071444 | ||
Primary structure of the cytochrome c from the snapping turtle, Chelydra serpentina | Q72920679 | ||
Relationship between the peptide-sensitive channel and the mitochondrial outer membrane protein translocation machinery | Q73084816 | ||
Overexpression of Bcl-2 suppresses the calcium activation of a mitochondrial megachannel | Q73935936 | ||
Mitochondrial presequences | Q77207198 | ||
Modulation of cell calcium signals by mitochondria | Q77327608 | ||
Tim17p regulates the twin pore structure and voltage gating of the mitochondrial protein import complex TIM23 | Q79407665 | ||
Awaking TIM22, a dynamic ligand-gated channel for protein insertion in the mitochondrial inner membrane | Q80226294 | ||
Mitochondrial deafness | Q80297869 | ||
Cardioprotective effects of BMS-180448, a prototype mitoK(ATP) channel opener, and the role of salvage kinases, in the rat model of global ischemia and reperfusion heart injury | Q80577265 | ||
A pharmacologic target of G3139 in melanoma cells may be the mitochondrial VDAC. | Q34624645 | ||
Is mPTP the gatekeeper for necrosis, apoptosis, or both? | Q34630758 | ||
What is the mitochondrial permeability transition pore? | Q34658211 | ||
Mitochondrial apoptosis-induced channel (MAC) function triggers a Bax/Bak-dependent bystander effect. | Q34760689 | ||
Cyclosporine A treatment for Ullrich congenital muscular dystrophy: a cellular study of mitochondrial dysfunction and its rescue | Q34882389 | ||
MAC inhibitors suppress mitochondrial apoptosis | Q34998219 | ||
The BCL-2 family reunion | Q35568029 | ||
Adenine nucleotide translocator 1 deficiency increases resistance of mouse brain and neurons to excitotoxic insults. | Q35632870 | ||
Outer mitochondrial membrane permeability can regulate coupled respiration and cell survival | Q35690379 | ||
Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures | Q35699506 | ||
Mitochondrial calcium and oxidative stress as mediators of ischemic brain injury. | Q35839931 | ||
Mitochondrial mechanisms of neural cell apoptosis | Q35876358 | ||
Chopped, trapped or tacked--protein translocation into the IMS of mitochondria | Q36092045 | ||
Regulated targeting of BAX to mitochondria. | Q36255507 | ||
On the role of VDAC in apoptosis: fact and fiction | Q36259127 | ||
Tim23, a protein import component of the mitochondrial inner membrane, is required for normal activity of the multiple conductance channel, MCC. | Q36273797 | ||
Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme | Q36371649 | ||
The mitochondrial permeability transition from in vitro artifact to disease target | Q36464595 | ||
Bcl-2-family proteins and hematologic malignancies: history and future prospects | Q36508817 | ||
The role of mitochondria in inherited neurodegenerative diseases | Q36521932 | ||
The role of mitochondria in apoptosis*. | Q36602674 | ||
The mitochondrial permeability transition in neurologic disease | Q36775895 | ||
Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes | Q36799170 | ||
Superoxide flashes in single mitochondria | Q36900957 | ||
BCL-2 family proteins: critical checkpoints of apoptotic cell death | Q37038230 | ||
Diagnosing and exploiting cancer's addiction to blocks in apoptosis | Q37059647 | ||
The p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage | Q37079047 | ||
Assembly of the mitochondrial apoptosis-induced channel, MAC. | Q37169502 | ||
Mitochondrial voltage-dependent anion channels (VDACs) as novel pharmacological targets for anti-cancer agents | Q37243963 | ||
Bcl-2 potentiates the maximal calcium uptake capacity of neural cell mitochondria | Q37366855 | ||
Characteristics and possible functions of mitochondrial Ca(2+) transport mechanisms | Q37375152 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | reperfusion injury | Q1413991 |
neurodegeneration | Q1755122 | ||
P304 | page(s) | 14-23 | |
P577 | publication date | 2011-03-23 | |
P1433 | published in | Mitochondrion | Q2122381 |
P1476 | title | The therapeutic potential of mitochondrial channels in cancer, ischemia-reperfusion injury, and neurodegeneration | |
P478 | volume | 12 |