scholarly article | Q13442814 |
P50 | author | Zsuzsanna Izsvák | Q21264884 |
Wei Chen | Q30504047 | ||
Zoltán Ivics | Q62559996 | ||
Andreas Gogol-Döring | Q84472583 | ||
Toni Cathomen | Q37840253 | ||
P2093 | author name string | Csaba Miskey | |
Ismahen Ammar | |||
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Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system | Q24631198 | ||
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Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains | Q24655087 | ||
Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes | Q24657906 | ||
Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses | Q24684749 | ||
Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences | Q24798872 | ||
High-resolution profiling of histone methylations in the human genome | Q27860906 | ||
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome | Q28131828 | ||
Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates | Q28243550 | ||
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1 | Q28290118 | ||
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Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells | Q29617246 | ||
Transcription start regions in the human genome are favored targets for MLV integration | Q29618456 | ||
HIV-1 integration in the human genome favors active genes and local hotspots | Q29618457 | ||
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Stem-cell gene therapy for the Wiskott-Aldrich syndrome | Q33392766 | ||
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Adeno-associated viral vectors for gene transfer and gene therapy | Q33701559 | ||
LEDGF hybrids efficiently retarget lentiviral integration into heterochromatin | Q33731166 | ||
A chimeric protein containing the N terminus of the adeno-associated virus Rep protein recognizes its target site in an in vivo assay | Q33799084 | ||
How adeno-associated virus Rep78 protein arrests cells completely in S phase | Q34015943 | ||
Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease | Q34094502 | ||
Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition | Q34135093 | ||
A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19. | Q34156171 | ||
Gene transfer efficiency and genome-wide integration profiling of Sleeping Beauty, Tol2, and piggyBac transposons in human primary T cells | Q34183381 | ||
Hyperactive sleeping beauty transposase enables persistent phenotypic correction in mice and a canine model for hemophilia B. | Q34343757 | ||
Tn7: smarter than we thought | Q34443592 | ||
Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial | Q34640765 | ||
Use of the piggyBac transposon for germ-line transformation of insects | Q34843379 | ||
piggyBac is a flexible and highly active transposon as compared to sleeping beauty, Tol2, and Mos1 in mammalian cells | Q35108048 | ||
Comparative genomic integration profiling of Sleeping Beauty transposons mobilized with high efficacy from integrase-defective lentiviral vectors in primary human cells | Q35144439 | ||
Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage | Q35290320 | ||
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences | Q35637501 | ||
Adeno-associated virus vectors preferentially transduce cells in S phase. | Q35754006 | ||
Site-directed transposon integration in human cells | Q35804718 | ||
Site-specific integration by adeno-associated virus is directed by a cellular DNA sequence | Q35829692 | ||
Sequence requirements for binding of Rep68 to the adeno-associated virus terminal repeats | Q35856414 | ||
Binding sites for adeno-associated virus Rep proteins within the human genome. | Q35879908 | ||
Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus | Q36159178 | ||
Tol2: a versatile gene transfer vector in vertebrates | Q36187507 | ||
Efficient nonviral Sleeping Beauty transposon-based TCR gene transfer to peripheral blood lymphocytes confers antigen-specific antitumor reactivity. | Q36311669 | ||
Interaction of the adeno-associated virus Rep protein with a sequence within the A palindrome of the viral terminal repeat. | Q36624790 | ||
Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system | Q36713904 | ||
Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients | Q36812729 | ||
Healing the wounds inflicted by sleeping beauty transposition by double-strand break repair in mammalian somatic cells. | Q51829783 | ||
Transposition and targeting of the prokaryotic mobile element IS30 in zebrafish. | Q54519665 | ||
An engineered four-stranded coiled coil substitutes for the tetramerization domain of wild-type p53 and alleviates transdominant inhibition by tumor-derived p53 mutants | Q70866376 | ||
Altering the insertional specificity of a Drosophila transposable element | Q36869160 | ||
Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding | Q36995336 | ||
Targeted gene insertion for molecular medicine | Q37209562 | ||
Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice | Q37241328 | ||
Retroviral Vectors for Gene Therapy | Q37809064 | ||
Modulating target site selection during human immunodeficiency virus DNA integration in vitro with an engineered tethering factor | Q38309659 | ||
Site-specific integration of a transgene mediated by a hybrid adenovirus/adeno-associated virus vector using the Cre/loxP-expression-switching system | Q38310905 | ||
Targeted Sleeping Beauty transposition in human cells | Q38480971 | ||
Manipulating piggyBac transposon chromosomal integration site selection in human cells | Q38585848 | ||
Precise targeted integration by a chimaeric transposase zinc-finger fusion protein. | Q39373164 | ||
Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p | Q39528168 | ||
Adeno-associated virus as a vector for liver-directed gene therapy. | Q39583470 | ||
Sustained FVIII expression and phenotypic correction of hemophilia A in neonatal mice using an endothelial-targeted sleeping beauty transposon | Q40319528 | ||
A role for LEDGF/p75 in targeting HIV DNA integration | Q40346940 | ||
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice | Q40386192 | ||
Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference. | Q40452758 | ||
Site-specific integration of functional transgenes into the human genome by adeno/AAV hybrid vectors. | Q40510442 | ||
AAV serotype 2 vectors preferentially integrate into active genes in mice | Q40643545 | ||
Adeno-associated virus: integration at a specific chromosomal locus | Q40852243 | ||
Precise excision of TTAA-specific lepidopteran transposons piggyBac (IFP2) and tagalong (TFP3) from the baculovirus genome in cell lines from two species of Lepidoptera | Q41201975 | ||
Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration | Q41431346 | ||
Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system | Q41734970 | ||
Insulin expression in livers of diabetic mice mediated by hydrodynamics-based administration | Q41848708 | ||
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain | Q42280576 | ||
In vivo correction of murine tyrosinemia type I by DNA-mediated transposition. | Q44260023 | ||
RAC reviews serious adverse event associated with AAV therapy trial | Q44304216 | ||
CD8(+) T-cell responses to adeno-associated virus capsid in humans | Q45406111 | ||
Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements. | Q45855517 | ||
High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR). | Q45873348 | ||
Targeted integration of foreign DNA into a defined locus on chromosome 19 in K562 cells using AAV-derived components | Q45879173 | ||
Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system | Q45879828 | ||
Target-site preferences of Sleeping Beauty transposons. | Q45880767 | ||
Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma | Q45886735 | ||
Requirement of RNA polymerase III transcription factors for in vitro position-specific integration of a retroviruslike element | Q46798246 | ||
Stable nonviral genetic correction of inherited human skin disease | Q46930709 | ||
Insertion of a novel transposable element in the tyrosinase gene is responsible for an albino mutation in the medaka fish, Oryzias latipes | Q48068575 | ||
P275 | copyright license | Creative Commons Attribution-NonCommercial 3.0 Unported | Q18810331 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 14 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 6693-6712 | |
P577 | publication date | 2012-04-19 | |
P1433 | published in | Nucleic Acids Research | Q135122 |
P1476 | title | Retargeting transposon insertions by the adeno-associated virus Rep protein | |
P478 | volume | 40 |
Q38895305 | A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition |
Q35107224 | A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells |
Q92818897 | A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells |
Q26781121 | Applications of DNA integrating elements: Facing the bias bully |
Q40139400 | Comparative analysis of chimeric ZFP-, TALE- and Cas9-piggyBac transposases for integration into a single locus in human cells |
Q51744631 | Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors. |
Q37718218 | Engineering of PEDF-Expressing Primary Pigment Epithelial Cells by the SB Transposon System Delivered by pFAR4 Plasmids |
Q47386205 | Evaluating different DNA binding domains to modulate L1 ORF2p-driven site-specific retrotransposition events in human cells. |
Q36698269 | Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy |
Q35891332 | Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4(+) T Cells. |
Q35413268 | Genomic analysis of Sleeping Beauty transposon integration in human somatic cells |
Q33801920 | Genomic landscape of human, bat, and ex vivo DNA transposon integrations |
Q42231746 | Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons. |
Q42231749 | Germline transgenesis in rabbits by pronuclear microinjection of Sleeping Beauty transposons. |
Q42231754 | Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons. |
Q90149917 | Jump around: transposons in and out of the laboratory |
Q36856042 | New Wistar Kyoto and spontaneously hypertensive rat transgenic models with ubiquitous expression of green fluorescent protein |
Q92345021 | Preclinical Evaluation of a Cell-Based Gene Therapy Using the Sleeping Beauty Transposon System in Choroidal Neovascularization |
Q92244370 | RNA-guided piggyBac transposition in human cells |
Q90109113 | RNA-guided retargeting of Sleeping Beauty transposition in human cells |
Q35229905 | Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens |
Q38970768 | Sleeping Beauty transposition: from biology to applications. |
Q41999327 | Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells. |
Q35119789 | Suicidal autointegration of sleeping beauty and piggyBac transposons in eukaryotic cells |
Q38529269 | TRIP through the chromatin: a high throughput exploration of enhancer regulatory landscapes. |
Q92724071 | Targeted DNA transposition in vitro using a dCas9-transposase fusion protein |
Q38937542 | The Tol2 transposon system mediates the genetic engineering of T-cells with CD19-specific chimeric antigen receptors for B-cell malignancies |
Q64112074 | The impact of transposable element activity on therapeutically relevant human stem cells |
Q37236764 | Transcription activator like effector (TALE)-directed piggyBac transposition in human cells |
Q36615157 | Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. |
Q50188279 | Transposons As Tools for Functional Genomics in Vertebrate Models |
Q38997139 | Using TRIP for genome-wide position effect analysis in cultured cells |