Adrenergic Receptor Polymorphism and Maximal Exercise Capacity after Orthotopic Heart Transplantation

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Adrenergic Receptor Polymorphism and Maximal Exercise Capacity after Orthotopic Heart Transplantation is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1163475M
P356DOI10.1371/JOURNAL.PONE.0163475
P932PMC publication ID5036840
P698PubMed publication ID27669015

P50authorMélanie MétrichQ40394406
P2093author name stringDavid Martin
Roger Hullin
Philippe Meyer
Swiss Transplant Cohort Study
Julien Regamey
Piergiorgio Tozzi
Fortesa Mehmeti
Helene Feliciano
P2860cites workA four amino acid deletion polymorphism in the third intracellular loop of the human alpha 2C-adrenergic receptor confers impaired coupling to multiple effectorsQ33901100
Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humansQ34414732
A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failureQ34872068
Cardiovascular pharmacogenomics of adrenergic receptor signaling: clinical implications and future directionsQ35033003
Exercise after heart transplantation.Q35299014
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Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejectionQ36317528
Beta-adrenergic receptor polymorphisms and cardiac graft function in potential organ donorsQ36442614
Cardiac motion tracking using CINE harmonic phase (HARP) magnetic resonance imagingQ36942848
Clinician's Guide to cardiopulmonary exercise testing in adults: a scientific statement from the American Heart AssociationQ37768298
Polymorphic variants of adrenoceptors: pharmacology, physiology, and role in diseaseQ38220135
The Registry of the International Society for Heart and Lung Transplantation: Thirty-second Official Adult Heart Transplantation Report--2015; Focus Theme: Early Graft Failure.Q40445087
Hierarchy of polymorphic variation and desensitization permutations relative to beta 1- and beta 2-adrenergic receptor signalingQ40678123
Neurotransmitter depletion compromises the ability of indirect-acting amines to provide inotropic support in the failing human heartQ41173328
Functional responses of human beta1 adrenoceptors with defined haplotypes for the common 389R>G and 49S>G polymorphisms.Q42464424
The myocardium-protective Gly-49 variant of the beta 1-adrenergic receptor exhibits constitutive activity and increased desensitization and down-regulationQ42521824
The heart rate response to exercise and circulating catecholamines in heart transplant recipientsQ43865810
Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypesQ44451939
The Arg16Gly-β2-adrenoceptor single nucleotide polymorphism: exercise capacity and survival in patients with end-stage heart failureQ44458675
Thr164Ile polymorphism of the human beta2-adrenoceptor exhibits blunted desensitization of cardiac functional responses in vivoQ44517355
Arg16/Gly beta2-adrenergic receptor polymorphism alters the cardiac output response to isometric exerciseQ46580554
Heart rate reduction after heart transplantation with beta-blocker versus the selective If channel antagonist ivabradine.Q46909671
Predictors of exercise capacity and the impact of angiographic coronary artery disease in heart transplant recipientsQ47302075
True myocardial motion trackingQ49148157
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Impaired exercise capacity late after cardiac transplantation: influence of chronotropic incompetence, hypertension, and calcium channel blockers.Q50866718
Exercise capacity after heart transplantation: influence of donor and recipient characteristics.Q51008023
Steady-state free precession with myocardial tagging: CSPAMM in a single breathhold.Q51680935
Myocardial catecholamine content after heart transplantation.Q53033040
Association of beta-adrenergic receptor polymorphisms and progression to heart failure in patients with idiopathic dilated cardiomyopathy.Q54698967
Diastolic Dysfunction of the Cardiac Allograft and Maximal Exercise CapacityQ58020062
In vivo measurement of neuronal uptake of norepinephrine in the human heartQ68409740
Decreased adenylate cyclase activity and expression of Gs alpha in human myocardium after orthotopic cardiac transplantationQ72187834
Coexistence of functioning beta 1- and beta 2-adrenoceptors in single myocytes from human ventricleQ72228925
Kinetics of heart rate and catecholamines during exercise in humans. The effect of heart denervationQ72886629
Long-term sequential changes in exercise capacity and chronotropic responsiveness after cardiac transplantationQ73542977
Predictive factors of maximal aerobic capacity after cardiac transplantationQ73948835
Polymorphisms of the beta1-adrenergic receptor predict exercise capacity in heart failureQ78489517
Clinical predictors of exercise capacity 1 year after cardiac transplantationQ78805279
Different evolutions in heart rate variability after heart transplantation: 10-year follow-upQ81145469
Cardiac reserve in the transplanted heart: effect of a graft polymorphism in the beta1-adrenoceptorQ81228052
The CAREGENE study: polymorphisms of the beta1-adrenoceptor gene and aerobic power in coronary artery diseaseQ82297420
Abnormal end-tidal PO(2) and PCO(2) at the anaerobic threshold correlate well with impaired exercise gas exchange in patients with left ventricular dysfunctionQ82560699
Response to catecholamine stimulation of polymorphisms of the beta-1 and beta-2 adrenergic receptorsQ84484509
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)e0163475
P577publication date2016-09-26
P1433published inPLOS OneQ564954
P1476titleAdrenergic Receptor Polymorphism and Maximal Exercise Capacity after Orthotopic Heart Transplantation
P478volume11

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