scholarly article | Q13442814 |
P356 | DOI | 10.1002/DMRR.566 |
P698 | PubMed publication ID | 15926190 |
P2093 | author name string | Bernard Portha | |
P2860 | cites work | Genomic imprinting and epigenetic reprogramming: unearthing the garden of forking paths | Q28202464 |
The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man | Q28207622 | ||
Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis | Q29615808 | ||
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes | Q29619192 | ||
Decreased pancreatic islet response to L-leucine in the spontaneously diabetic GK rat: enzymatic, metabolic and secretory data | Q30581732 | ||
Searching for type 2 diabetes genes in the post-genome era. | Q34066598 | ||
Gestational diabetes leads to the development of diabetes in adulthood in the rat. | Q34125696 | ||
Metabolic programming: causes and consequences | Q34430909 | ||
Maturity-onset diabetes of the young: a clinical history | Q34457160 | ||
Diabetes mellitus and genetically programmed defects in beta-cell function | Q34462316 | ||
Mitochondrial function in normal and diabetic beta-cells | Q34462332 | ||
Genetic approaches to the molecular understanding of type 2 diabetes | Q34731596 | ||
For debate: Fetal and early postnatal growth restriction lead to diabetes, the metabolic syndrome and renal failure. | Q35162950 | ||
Impaired pancreatic beta cell function in the fetal GK rat. Impact of diabetic inheritance | Q37378354 | ||
Maternal diabetes during pregnancy: consequences for the offspring. | Q37797291 | ||
Mutations in the promoter of adenylyl cyclase (AC)-III gene, overexpression of AC-III mRNA, and enhanced cAMP generation in islets from the spontaneously diabetic GK rat model of type 2 diabetes | Q38338987 | ||
Insulin-degrading enzyme identified as a candidate diabetes susceptibility gene in GK rats | Q40859035 | ||
Maternally inherited diabetes and deafness: a new diabetes subtype | Q41088487 | ||
Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat. | Q42443185 | ||
Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes | Q42475849 | ||
Defective glucose-dependent cytosolic Ca2+ handling in islets of GK and nSTZ rat models of type 2 diabetes | Q42501182 | ||
beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony | Q42501772 | ||
Zinc depletion reduced Egr-1 and HNF-3beta expression and apolipoprotein A-I promoter activity in Hep G2 cells | Q42523430 | ||
Hyperglycemia contributes to impaired insulin response in GK rat islets | Q43555575 | ||
Impaired pancreatic duct-cell growth in focal areas of regeneration after partial pancreatectomy in the adult Goto-Kakizaki rat, a spontaneous model of non-insulin dependent diabetes mellitus | Q43709102 | ||
Impaired beta-cell regeneration after partial pancreatectomy in the adult Goto-Kakizaki rat, a spontaneous model of type II diabetes | Q43783938 | ||
Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats | Q43808950 | ||
Inheritance of diabetes mellitus as consequence of gestational hyperglycemia in rats | Q43811449 | ||
Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats | Q43901591 | ||
Abnormal expression of pancreatic islet exocytotic soluble N-ethylmaleimide-sensitive factor attachment protein receptors in Goto-Kakizaki rats is partially restored by phlorizin treatment and accentuated by high glucose treatment | Q44193765 | ||
Enhanced insulin secretion and cholesterol metabolism in congenic strains of the spontaneously diabetic (Type 2) Goto Kakizaki rat are controlled by independent genetic loci in rat chromosome 8. | Q44911368 | ||
Type 2 diabetes mellitus--genes or intrauterine environment? An embryo transfer paradigm in rats. | Q44982604 | ||
Diabetes in pregnancy: effects on the foetal and newborn rat with particular regard to body weight, serum insulin concentration and pancreatic contents of insulin, glucagon and somatostatin | Q47293878 | ||
Disturbed development of the preimplantation embryo in the insulin-dependent diabetic BB/E rat. | Q47870454 | ||
Genetic analysis of non-insulin dependent diabetes mellitus in the GK rat. | Q51584099 | ||
Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea | Q57214866 | ||
Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat | Q63432900 | ||
The endocrine pancreas of the fetus from diabetic pregnant rat | Q67436756 | ||
Effect of a low protein diet during pregnancy on the fetal rat endocrine pancreas | Q68495936 | ||
Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins | Q68535734 | ||
Impaired glucose homeostasis in adult rats from hyperglycemic mothers | Q68895015 | ||
Diabetes in identical twins. A study of 200 pairs | Q70659026 | ||
Folate, DNA methylation, and gene expression: factors of nature and nurture | Q73019065 | ||
Pathophysiological and genetic characterization of the major diabetes locus in GK rats | Q73224803 | ||
Hyperglycemic crises in patients with diabetes mellitus | Q73548236 | ||
Early development of beta-cells is impaired in the GK rat model of type 2 diabetes | Q73680089 | ||
Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects | Q76385432 | ||
Beta-cell growth in the neonatal Goto-Kakisaki rat and regeneration after treatment with streptozotocin at birth | Q78126454 | ||
Age-dependent inability of the endocrine pancreas to adapt to pregnancy: a long-term consequence of perinatal malnutrition in the rat | Q78180951 | ||
P433 | issue | 6 | |
P921 | main subject | type 2 diabetes | Q3025883 |
P304 | page(s) | 495-504 | |
P577 | publication date | 2005-11-01 | |
P1433 | published in | Diabetes - Metabolism: Research and Reviews | Q15750056 |
P1476 | title | Programmed disorders of beta-cell development and function as one cause for type 2 diabetes? The GK rat paradigm | |
P478 | volume | 21 |
Q50421467 | A 'phenotypic hangover': the predictive adaptive response and multigenerational effects of altered nutrition on the transcriptome of Drosophila melanogaster |
Q28742364 | Adipose tissue deficiency and chronic inflammation in diabetic Goto-Kakizaki rats |
Q47663822 | Alterations of Brain Energy Metabolism in Type 2 Diabetic Goto-Kakizaki Rats Measured In Vivo by (13)C Magnetic Resonance Spectroscopy. |
Q49952246 | Animal models of obesity and diabetes mellitus |
Q36296022 | Ca2+-secretion coupling is impaired in diabetic Goto Kakizaki rats |
Q97078276 | Characterization of an i.p. D-galactose-induced cataract model in rats |
Q30497268 | Chromosomal mapping of pancreatic islet morphological features and regulatory hormones in the spontaneously diabetic (Type 2) Goto-Kakizaki rat |
Q46039868 | Clock gene expression in the liver and adipose tissues of non-obese type 2 diabetic Goto-Kakizaki rats. |
Q47127780 | Comparison of Goto-Kakizaki rats and high fat diet-induced obese rats: Are they reliable models to study Type 2 Diabetes mellitus? |
Q36783750 | Dietary-resistant starch improves maternal glycemic control in Goto-Kakizaki rat. |
Q34978418 | Differential muscle gene expression as a function of disease progression in Goto-Kakizaki diabetic rats |
Q45936695 | Distinct genetic regulation of progression of diabetes and renal disease in the Goto-Kakizaki rat. |
Q35944949 | Effects of High Fat Feeding on Adipose Tissue Gene Expression in Diabetic Goto-Kakizaki Rats |
Q37210037 | Effects of diabetes on hippocampal neurogenesis: links to cognition and depression |
Q36450303 | Effects of high fat feeding on liver gene expression in diabetic goto-kakizaki rats |
Q82862981 | Epigenetics in mammary gland biology and cancer |
Q34498189 | Erectile dysfunction in young non-obese type II diabetic Goto-Kakizaki rats is associated with decreased eNOS phosphorylation at Ser1177 |
Q46969686 | Expression of hepatic antioxidant enzymes in non-obese type-2 diabetic Goto-Kakizaki rats |
Q33718965 | GPR40 partial agonist MK-2305 lower fasting glucose in the Goto Kakizaki rat via suppression of endogenous glucose production. |
Q63432883 | Genetic control of plasma lipid levels in a cross derived from normoglycaemic Brown Norway and spontaneously diabetic Goto–Kakizaki rats |
Q42557992 | Hypoglycemic effect of Chlorella vulgaris intake in type 2 diabetic Goto-Kakizaki and normal Wistar rats |
Q37310711 | IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat |
Q35658153 | Insulin Resistance Is Not Associated with an Impaired Mitochondrial Function in Contracting Gastrocnemius Muscle of Goto-Kakizaki Diabetic Rats In Vivo |
Q33989455 | Interleukin-1/toll-like receptor-induced nuclear factor kappa B signaling participates in intima hyperplasia after carotid artery balloon injury in goto-kakizaki rats: a potential target therapy pathway |
Q36369096 | Islet Stellate Cells Isolated from Fibrotic Islet of Goto-Kakizaki Rats Affect Biological Behavior of Beta-Cell |
Q51368612 | Linking biological activity with herbal constituents by systems biology-based approaches: effects of Panax ginseng in type 2 diabetic Goto-Kakizaki rats. |
Q38014678 | Mapping genetic determinants of kidney damage in rat models. |
Q37055749 | Mechanism-based disease progression modeling of type 2 diabetes in Goto-Kakizaki rats |
Q34822513 | Mechanistic population modeling of diabetes disease progression in Goto-Kakizaki rat muscle |
Q42914578 | Mitochondrial nutrients improve immune dysfunction in the type 2 diabetic Goto-Kakizaki rats. |
Q42442347 | Nupr1 deletion protects against glucose intolerance by increasing beta cell mass |
Q46039814 | Pharmacokinetics of nateglinide enantiomers and their metabolites in Goto-Kakizaki rats, a model for type 2 diabetes mellitus. |
Q61805168 | Protective Effect of Resveratrol against Ischemia-Reperfusion Injury via Enhanced High Energy Compounds and eNOS-SIRT1 Expression in Type 2 Diabetic Female Rat Heart |
Q33597948 | Proteome, phosphoproteome, and hydroxyproteome of liver mitochondria in diabetic rats at early pathogenic stages |
Q36263008 | Proteomic Analysis of One-carbon Metabolism-related Marker in Liver of Rat Offspring. |
Q37259948 | Ranking candidate genes in rat models of type 2 diabetes |
Q37407878 | Rat models for bariatric surgery and surgery for type 2 diabetes mellitus |
Q28468578 | Reduced up-regulation of the nitric oxide pathway and impaired endothelial and smooth muscle functions in the female type 2 diabetic goto-kakizaki rat heart |
Q33779672 | Small G proteins in islet beta-cell function |
Q34586474 | Sustained delivery of IL-1Ra from PF127-gel reduces hyperglycemia in diabetic GK-rats |
Q43294363 | The correlation between intestinal gonadotropin-releasing hormone (GnRH) and proglucagon in hyperlipidemic rats and Goto-Kakizaki (GK) rats |
Q47174040 | The effects of hypoglycemia and weight loss of total lignans from Fructus Arctii in KKAy mice and its mechanisms of the activity. |
Q36879892 | The novel oral drug Subetta exerts an antidiabetic effect in the diabetic Goto-Kakizaki rat: comparison with rosiglitazone. |
Q45753845 | Up-regulation of stearoyl-CoA desaturase 1 increases liver MUFA content in obese Zucker but not Goto-Kakizaki rats |
Q34357863 | Upregulation of eNOS and unchanged energy metabolism in increased susceptibility of the aging type 2 diabetic GK rat heart to ischemic injury |
Q36473655 | What is an epigenetic transgenerational phenotype? F3 or F2. |
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