review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Julia K Archbold | Q56826702 |
James Barwell | Q117263046 | ||
Debbie Hay | Q37829061 | ||
David R Poyner | Q37829072 | ||
Joseph Gingell | Q59560340 | ||
P2093 | author name string | Harriet A Watkins | |
P2860 | cites work | The mid-region of parathyroid hormone (1-34) serves as a functional docking domain in receptor activation. | Q53552116 |
A Structural Basis for Sequence Comparisons | Q56915250 | ||
The N-Terminal Extracellular Domain 23−60 of the Calcitonin Receptor-Like Receptor in Chimeras with the Parathyroid Hormone Receptor Mediates Association with Receptor Activity-Modifying Protein 1† | Q58185840 | ||
Characterization of parathyroid hormone/receptor interactions: structure of the first extracellular loop | Q73977450 | ||
Contribution of the second transmembrane helix of the secretin receptor to the positioning of secretin | Q74432807 | ||
The role of the fourth extracellular domain of the rat corticotropin-releasing factor receptor type 1 in ligand binding | Q77892735 | ||
Class-B GPCR activation: is ligand helix-capping the key? | Q81459822 | ||
Identification and pharmacological characterization of domains involved in binding of CGRP receptor antagonists to the calcitonin-like receptor | Q82476591 | ||
Conformation of a peptide ligand bound to its G-protein coupled receptor | Q24290821 | ||
Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2 | Q24295086 | ||
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor | Q24323946 | ||
Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptor | Q24644625 | ||
Dimeric Arrangement of the Parathyroid Hormone Receptor and a Structural Mechanism for Ligand-induced Dissociation | Q27659967 | ||
Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism | Q27664362 | ||
Converting the Highly Amyloidogenic Human Calcitonin into a Powerful Fibril Inhibitor by Three-dimensional Structure Homology with a Non-amyloidogenic Analogue | Q27665898 | ||
Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors | Q27668088 | ||
Structure of the integral membrane domain of the GLP1 receptor | Q28138164 | ||
Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes | Q28184238 | ||
International Union of Pharmacology. XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors | Q28201576 | ||
Three distinct epitopes on the extracellular face of the glucagon receptor determine specificity for the glucagon amino terminus | Q28201902 | ||
Functional segregation of the highly conserved basic motifs within the third endoloop of the human secretin receptor | Q28214136 | ||
Novel receptor partners and function of receptor activity-modifying proteins | Q28215813 | ||
Functional calcitonin gene-related peptide receptors are formed by the asymmetric assembly of a calcitonin receptor-like receptor homo-oligomer and a monomer of receptor activity-modifying protein-1 | Q28245013 | ||
Pattern of intra-family hetero-oligomerization involving the G-protein-coupled secretin receptor | Q37430299 | ||
The second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression | Q38318694 | ||
Alanine scanning mutagenesis of the second extracellular loop of type 1 corticotropin-releasing factor receptor revealed residues critical for peptide binding | Q39898479 | ||
Diverse Functional Motifs within the Three Intracellular Loops of the CGRP1Receptor† | Q60665822 | ||
Functionally different isoforms of the human calcitonin receptor result from alternative splicing of the gene transcript | Q71523035 | ||
Full activation of chimeric receptors by hybrids between parathyroid hormone and calcitonin. Evidence for a common pattern of ligand-receptor interaction | Q71742566 | ||
Scanning of the glucagon-like peptide-1 receptor localizes G protein-activating determinants primarily to the N terminus of the third intracellular loop | Q73202207 | ||
Role of charged amino acids conserved in the vasoactive intestinal polypeptide/secretin family of receptors on the secretin receptor functionality | Q73208211 | ||
Mutational Analysis of Extracellular Cysteine Residues of Rat Secretin Receptor Shows that Disulfide Bridges are Essential for Receptor Function | Q73483154 | ||
Residues in the membrane-spanning and extracellular loop regions of the parathyroid hormone (PTH)-2 receptor determine signaling selectivity for PTH and PTH-related peptide | Q73853906 | ||
Mapping the bimolecular interface of the parathyroid hormone (PTH)-PTH1 receptor complex: spatial proximity between Lys(27) (of the hormone principal binding domain) and leu(261) (of the first extracellular loop) of the human PTH1 receptor | Q73977445 | ||
GPCR modulation by RAMPs | Q28268136 | ||
Distinct receptor activity-modifying protein domains differentially modulate interaction with calcitonin receptors | Q28301498 | ||
Critical contributions of amino-terminal extracellular domains in agonist binding and activation of secretin and vasoactive intestinal polypeptide receptors. Studies of chimeric receptors | Q28303314 | ||
Divergent structural requirements exist for calcitonin receptor binding specificity and adenylate cyclase activation | Q28569619 | ||
The third cytoplasmic domain of the GLP-1[7-36 amide] receptor is required for coupling to the adenylyl cyclase system | Q28574405 | ||
Structure of the integral membrane domain of the GLP1 receptor | Q29540751 | ||
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints | Q29547321 | ||
Twilight zone of protein sequence alignments | Q29614388 | ||
Passing the baton in class B GPCRs: peptide hormone activation via helix induction? | Q30319107 | ||
A study of the membrane-water interface region of membrane proteins. | Q30350022 | ||
Importance of the extracellular loops in G protein-coupled receptors for ligand recognition and receptor activation | Q30522852 | ||
High-throughput modeling of human G-protein coupled receptors: amino acid sequence alignment, three-dimensional model building, and receptor library screening | Q31063961 | ||
Identification of specific calcitonin-like receptor residues important for calcitonin gene-related peptide high affinity binding | Q33246847 | ||
Mapping peptide hormone-receptor interactions using a disulfide-trapping approach | Q33331953 | ||
Secretin occupies a single protomer of the homodimeric secretin receptor complex: insights from photoaffinity labeling studies using dual sites of covalent attachment | Q33744723 | ||
A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation. | Q33779634 | ||
CGRP-RCP, a novel protein required for signal transduction at calcitonin gene-related peptide and adrenomedullin receptors. | Q33910430 | ||
Protein-protein interaction and not glycosylation determines the binding selectivity of heterodimers between the calcitonin receptor-like receptor and the receptor activity-modifying proteins | Q33949422 | ||
The delta e13 isoform of the calcitonin receptor forms a six-transmembrane domain receptor with dominant-negative effects on receptor surface expression and signaling. | Q34063180 | ||
Importance of lipid-exposed residues in transmembrane segment four for family B calcitonin receptor homo-dimerization | Q34079450 | ||
Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints | Q34143310 | ||
GCRDb: a G-protein-coupled receptor database | Q34333530 | ||
A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors. | Q34379110 | ||
Ligand binding and activation of the CGRP receptor. | Q34654527 | ||
Refinement of glucagon-like peptide 1 docking to its intact receptor using mid-region photolabile probes and molecular modeling | Q34963202 | ||
Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors | Q36088758 | ||
The membrane-water interface region of membrane proteins: structural bias and the anti-snorkeling effect | Q36151469 | ||
Conformational changes in the parathyroid hormone receptor associated with activation by agonist | Q36629313 | ||
The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. | Q36693902 | ||
Structural characterization of the parathyroid hormone receptor domains determinant for ligand binding | Q36883912 | ||
Molecular mechanisms involved in vasoactive intestinal peptide receptor activation and regulation: current knowledge, similarities to and differences from the A family of G-protein-coupled receptors | Q36883918 | ||
Computational studies of Family A and Family B GPCRs | Q36883937 | ||
PTH and PTH antagonist induce different conformational changes in the PTHR1 receptor | Q37166813 | ||
Modulating receptor function through RAMPs: can they represent drug targets in themselves? | Q37371266 | ||
Juxtamembranous region of the amino terminus of the family B G protein-coupled calcitonin receptor plays a critical role in small-molecule agonist action | Q37372130 | ||
Photoaffinity cross-linking of the corticotropin-releasing factor receptor type 1 with photoreactive urocortin analogues. | Q40349088 | ||
Molecular and functional characterization of adrenomedullin receptors in pufferfish | Q40367201 | ||
Contribution of the carboxyl terminus of the VPAC1 receptor to agonist-induced receptor phosphorylation, internalization, and recycling | Q40414038 | ||
Molecular approximation between a residue in the amino-terminal region of calcitonin and the third extracellular loop of the class B G protein-coupled calcitonin receptor | Q40553493 | ||
Met-204 and Tyr-205 are together important for binding GLP-1 receptor agonists but not their N-terminally truncated analogues | Q40589773 | ||
Importance of the amino terminus in secretin family G protein-coupled receptors. Intrinsic photoaffinity labeling establishes initial docking constraints for the calcitonin receptor | Q40621953 | ||
The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge | Q40696352 | ||
Functional roles of conserved transmembrane prolines in the human VPAC(1) receptor | Q40785081 | ||
Mutations of the asparagine117 residue of a receptor activity-modifying protein 1-dependent human calcitonin gene-related peptide receptor result in selective loss of function | Q40809163 | ||
Determinants for calcitonin analog interaction with the calcitonin receptor N-terminus and transmembrane-loop regions | Q41155912 | ||
Multiple extracellular loop domains contribute critical determinants for agonist binding and activation of the secretin receptor | Q41190802 | ||
Mutations of neighboring polar residues on the second transmembrane helix disrupt signaling by the parathyroid hormone receptor | Q41231338 | ||
Truncation of the porcine calcitonin receptor cytoplasmic tail inhibits internalization and signal transduction but increases receptor affinity | Q41423560 | ||
Agonist-dependent consequences of proline to alanine substitution in the transmembrane helices of the calcitonin receptor | Q41587491 | ||
Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation | Q41670110 | ||
Structure of the parathyroid hormone receptor C terminus bound to the G-protein dimer Gbeta1gamma2. | Q41791755 | ||
Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor | Q41883095 | ||
Residue 17 of sauvagine cross-links to the first transmembrane domain of corticotropin-releasing factor receptor 1 (CRFR1). | Q41954586 | ||
The minor binding pocket: a major player in 7TM receptor activation | Q42876628 | ||
Mapping interaction sites within the N-terminus of the calcitonin gene-related peptide receptor; the role of residues 23-60 of the calcitonin receptor-like receptor | Q42933738 | ||
Evidence that interaction between conserved residues in transmembrane helices 2, 3, and 7 are crucial for human VPAC1 receptor activation | Q43007364 | ||
Mapping the CGRP receptor ligand binding domain: tryptophan-84 of RAMP1 is critical for agonist and antagonist binding | Q43148072 | ||
Two basic residues of the h-VPAC1 receptor second transmembrane helix are essential for ligand binding and signal transduction | Q43507743 | ||
Structure–function analysis of helix 8 of human calcitonin receptor-like receptor within the adrenomedullin 1 receptor | Q43532009 | ||
Functional and biophysical analysis of the C-terminus of the CGRP-receptor; a family B GPCR. | Q43616414 | ||
Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein | Q43626694 | ||
Sauvagine cross-links to the second extracellular loop of the corticotropin-releasing factor type 1 receptor | Q44005255 | ||
The alternatively spliced deltae13 transcript of the rabbit calcitonin receptor dimerizes with the C1a isoform and inhibits its surface expression | Q44397881 | ||
Identification of cytoplasmic domains of hVPAC1 receptor required for activation of adenylyl cyclase. Crucial role of two charged amino acids strictly conserved in class II G protein-coupled receptors. | Q44400097 | ||
Identification of a contact site for residue 19 of parathyroid hormone (PTH) and PTH-related protein analogs in transmembrane domain two of the type 1 PTH receptor | Q44567784 | ||
The positive charge at Lys-288 of the glucagon-like peptide-1 (GLP-1) receptor is important for binding the N-terminus of peptide agonists. | Q44627982 | ||
Aspartate(69) of the calcitonin-like receptor is required for its functional expression together with receptor-activity-modifying proteins 1 and -2. | Q44934476 | ||
Receptor activity-modifying proteins differentially modulate the G protein-coupling efficiency of amylin receptors | Q45711499 | ||
Dihydropyrrole[2,3-d]pyridine derivatives as novel corticotropin-releasing factor-1 antagonists: mapping of the receptor binding pocket by in silico docking studies | Q46271258 | ||
Effect of inactivating mutations on phosphorylation and internalization of the human VPAC2 receptor | Q46430496 | ||
Insights into interactions between the alpha-helical region of the salmon calcitonin antagonists and the human calcitonin receptor using photoaffinity labeling | Q46522310 | ||
Localization of agonist- and antagonist-binding domains of human corticotropin-releasing factor receptors | Q46679915 | ||
Methionine acts as a "magnet" in photoaffinity crosslinking experiments | Q46974696 | ||
Fluorescence resonance energy transfer analysis of secretin docking to its receptor: mapping distances between residues distributed throughout the ligand pharmacophore and distinct receptor residues. | Q51794822 | ||
The extreme N-terminus of the calcitonin-like receptor contributes to the selective interaction with adrenomedullin or calcitonin gene-related peptide. | Q51841685 | ||
The arrangement of the transmembrane helices in the secretin receptor family of G-protein-coupled receptors. | Q52867927 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | G protein-coupled receptor | Q38173 |
calcitonin receptor activity | Q14905622 | ||
P304 | page(s) | 51-65 | |
P577 | publication date | 2012-05-01 | |
P1433 | published in | British Journal of Pharmacology | Q919631 |
P1476 | title | Calcitonin and calcitonin receptor-like receptors: common themes with family B GPCRs? | |
P478 | volume | 166 |