HypoDE: Research Design and Methods of a Randomized Controlled Study Evaluating the Impact of Real-Time CGM Usage on the Frequency of CGM Glucose Values <55 mg/dl in Patients With Type 1 Diabetes and Problematic Hypoglycemia Treated With Multiple Da

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HypoDE: Research Design and Methods of a Randomized Controlled Study Evaluating the Impact of Real-Time CGM Usage on the Frequency of CGM Glucose Values <55 mg/dl in Patients With Type 1 Diabetes and Problematic Hypoglycemia Treated With Multiple Da is …
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scholarly articleQ13442814

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P356DOI10.1177/1932296815575999
P932PMC publication ID4604551
P698PubMed publication ID25759183
P5875ResearchGate publication ID273469789

P50authorLutz HeinemannQ65055050
P2093author name stringDavid Price
Norbert Hermanns
Andreas Liebl
Claudia Graham
Dorothee Deiss
Matthias Kaltheuner
P2860cites workEffect of sensor-augmented insulin pump therapy and automated insulin suspension vs standard insulin pump therapy on hypoglycemia in patients with type 1 diabetes: a randomized clinical trialQ38443982
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Structured treatment and teaching programs and an improvement in private health care lead to a better quality of diabetes care. JEVIN, a population-based trial 1989/90 up to 1999/2000Q44481107
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JDRF randomized clinical trial to assess the efficacy of real-time continuous glucose monitoring in the management of type 1 diabetes: research design and methodsQ46337569
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Recovery of hypoglycemia awareness in long-standing type 1 diabetes: a multicenter 2 × 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaSQ50642265
The U.K. service level audit of insulin pump therapy in adults.Q50764909
Threshold-based insulin-pump interruption for reduction of hypoglycemia.Q50888948
Severe hypoglycemic episodes: a persistent threat for children with Type 1 diabetes mellitus and their familiesQ56977700
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Meticulous prevention of hypoglycemia normalizes the glycemic thresholds and magnitude of most of neuroendocrine responses to, symptoms of, and cognitive function during hypoglycemia in intensively treated patients with short-term IDDMQ70495234
The relationship of glycemic exposure (HbA1c) to the risk of development and progression of retinopathy in the diabetes control and complications trialQ71919192
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Relative roles of insulin and hypoglycaemia on induction of neuroendocrine responses to, symptoms of, and deterioration of cognitive function in hypoglycaemia in male and female humansQ72877437
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Intensified insulin therapy and the risk of severe hypoglycaemiaQ73617182
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Nocturnal glucose control with an artificial pancreas at a diabetes campQ86210570
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Psychometric properties of the hypoglycemia fear survey-ii for adults with type 1 diabetesQ30427586
Reduced awareness of hypoglycemia in adults with IDDM. A prospective study of hypoglycemic frequency and associated symptomsQ30463772
Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapyQ30837772
Effectiveness of continuous glucose monitoring in a clinical care environment: evidence from the Juvenile Diabetes Research Foundation continuous glucose monitoring (JDRF-CGM) trialQ33556781
Improved results in paediatric diabetes care using a quality registry in an improvement collaborative: a case study in SwedenQ33670330
Glycaemic control in type 1 diabetes during real time continuous glucose monitoring compared with self monitoring of blood glucose: meta-analysis of randomised controlled trials using individual patient dataQ33954163
Hemoglobin A1c Levels and risk of severe hypoglycemia in children and young adults with type 1 diabetes from Germany and Austria: a trend analysis in a cohort of 37,539 patients between 1995 and 2012Q34301297
Youth and parent satisfaction with clinical use of the GlucoWatch G2 Biographer in the management of pediatric type 1 diabetesQ34482263
Response to nocturnal alarms using a real-time glucose sensorQ34696490
Effect of continuous glucose monitoring on hypoglycemia in type 1 diabetesQ34718324
Severe hypoglycemia and diabetic ketoacidosis in adults with type 1 diabetes: results from the T1D Exchange clinic registryQ34768952
Reducing rates of severe hypoglycemia in a population-based cohort of children and adolescents with type 1 diabetes over the decade 2000-2009Q35408129
Assessment of patient-led or physician-driven continuous glucose monitoring in patients with poorly controlled type 1 diabetes using basal-bolus insulin regimens: a 1-year multicenter studyQ35898281
Defining and reporting hypoglycemia in diabetes: a report from the American Diabetes Association Workgroup on HypoglycemiaQ36108419
The use and efficacy of continuous glucose monitoring in type 1 diabetes treated with insulin pump therapy: a randomised controlled trialQ36353388
System accuracy evaluation of 43 blood glucose monitoring systems for self-monitoring of blood glucose according to DIN EN ISO 15197.Q36605699
Comparative analysis of the efficacy of continuous glucose monitoring and self-monitoring of blood glucose in type 1 diabetes mellitus.Q36605704
Real-time improvement of continuous glucose monitoring accuracy: the smart sensor conceptQ36720416
The effect of continuous glucose monitoring in well-controlled type 1 diabetesQ37269538
Hypoglycemia: still the limiting factor in the glycemic management of diabetesQ37321737
Factors predictive of use and of benefit from continuous glucose monitoring in type 1 diabetesQ37400821
Incremental value of continuous glucose monitoring when starting pump therapy in patients with poorly controlled type 1 diabetes: the RealTrend studyQ37437141
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Methods for insulin delivery and glucose monitoring in diabetes: summary of a comparative effectiveness review.Q38044025
Mechanisms of hypoglycemia-associated autonomic failure in diabetesQ38123894
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A population-based study of risk factors for severe hypoglycaemia in a contemporary cohort of childhood-onset type 1 diabetesQ38425571
P433issue3
P407language of work or nameEnglishQ1860
P921main subjecttype-1 diabetesQ124407
hypoglycemiaQ202758
research designQ1438035
P304page(s)651-662
P577publication date2015-03-09
P1433published inJournal of Diabetes Science and TechnologyQ15755249
P1476titleHypoDE: Research Design and Methods of a Randomized Controlled Study Evaluating the Impact of Real-Time CGM Usage on the Frequency of CGM Glucose Values <55 mg/dl in Patients With Type 1 Diabetes and Problematic Hypoglycemia Treated With Multiple Da
P478volume9

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cites work (P2860)
Q55252190Healthcare Resource Waste Associated with Patient Nonadherence and Early Discontinuation of Traditional Continuous Glucose Monitoring in Real-World Settings: A Multicountry Analysis.
Q92174720Impact of CGM on the Management of Hypoglycemia Problems: Overview and Secondary Analysis of the HypoDE Study
Q49834635Real-time continuous glucose monitoring in adults with type 1 diabetes and impaired hypoglycaemia awareness or severe hypoglycaemia treated with multiple daily insulin injections (HypoDE): a multicentre, randomised controlled trial
Q37054685The Potential Cost Implications of Averting Severe Hypoglycemic Events Requiring Hospitalization in High-Risk Adults With Type 1 Diabetes Using Real-Time Continuous Glucose Monitoring

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