Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking

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Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking is …
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scholarly articleQ13442814

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P5530Altmetric DOI10.1182/BLOOD-2015-06-652263
P6179Dimensions Publication ID1064122742
P356DOI10.1182/BLOOD-2015-06-652263
P932PMC publication ID4608241
P698PubMed publication ID26324704
P1154Scopus EID2-s2.0-84944200239

P50authorYiming WangQ42158068
Heyu NiQ42158077
Cedric DuvalQ52584539
Robert A S AriënsQ53843830
Caroline E HansenQ64882406
Jcm MeijersQ68093274
Alisa S. WolbergQ86111693
P2093author name stringSusan T Lord
Wilbur A Lam
Jill M Johnsen
Martha A Clark
Byungwook Ahn
James R Byrnes
Micah J Mooberry
P2860cites workFibrin fibers have extraordinary extensibility and elasticityQ30479919
The mechanical properties of single fibrin fibers.Q30497764
Plasma fibronectin supports hemostasis and regulates thrombosisQ30590791
Changes in the properties of normal human red blood cells during in vivo agingQ33796195
Alpha2-antiplasmin gene deficiency in mice is associated with enhanced fibrinolytic potential without overt bleeding.Q33856100
The elasticity of an individual fibrin fiber in a clotQ33879142
Factor XIII activity mediates red blood cell retention in venous thrombiQ33944224
Venous thrombosisQ89217812
α-α Cross-links increase fibrin fiber elasticity and stiffnessQ34120791
Structural origins of fibrin clot rheologyQ34171813
Influence of a natural and a synthetic inhibitor of factor XIIIa on fibrin clot rheology.Q34171820
Host iron status and iron supplementation mediate susceptibility to erythrocytic stage Plasmodium falciparumQ34598503
Thrombin generation and fibrin clot structureQ34598931
Molecular mechanisms affecting fibrin structure and stabilityQ34759786
Causal relationship between hyperfibrinogenemia, thrombosis, and resistance to thrombolysis in miceQ35001664
Crosslinking and labeling of membrane proteins by transglutaminase-catalyzed reactionsQ35083581
Procoagulant activity induced by vascular injury determines contribution of elevated factor VIII to thrombosis and thrombus stability in mice.Q35346495
Platelet retraction force measurements using flexible post force sensorsQ37032473
Elevated prothrombin promotes venous, but not arterial, thrombosis in mice.Q37189156
Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stabilityQ37450566
Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin.Q37623550
Factor XIII: a coagulation factor with multiple plasmatic and cellular functionsQ37899674
Factor XIII deficiency: an update.Q38127624
Modification of human erythrocyte ghosts with transglutaminaseQ39066804
Mechanics and contraction dynamics of single platelets and implications for clot stiffeningQ39756732
Coagulation factor XIIIa substrates in human plasma: identification and incorporation into the clotQ41825512
Involvement of fibrinogen specific binding in erythrocyte aggregationQ41858099
The alphaC domains of fibrinogen affect the structure of the fibrin clot, its physical properties, and its susceptibility to fibrinolysisQ41938756
Atomic force microscopy-based molecular recognition of a fibrinogen receptor on human erythrocytesQ42929227
Altered plasma fibrin clot properties in patients with digestive tract cancers: links with the increased thrombin generationQ44059567
Integrin-associated protein (CD47) is a putative mediator for soluble fibrinogen interaction with human red blood cells membraneQ44159019
Bleeding and thrombosis in 55 patients with inherited afibrinogenaemiaQ45862883
High dose factor VIIa improves clot structure and stability in a model of haemophilia B.Q45889198
The effect of blood coagulation factor XIII on fibrin clot structure and fibrinolysis.Q45906428
Roles of fibrin α- and γ-chain specific cross-linking by FXIIIa in fibrin structure and function.Q52840471
Purification and characterization of recombinant human fibrinogen.Q54248130
Prolonged duration of type 2 diabetes is associated with increased thrombin generation, prothrombotic fibrin clot phenotype and impaired fibrinolysis.Q54489366
Novel Factor XIII Probes for Blood Coagulation ImagingQ58816212
Elevated prothrombin results in clots with an altered fiber structure: a possible mechanism of the increased thrombotic riskQ61405268
Titration of the acceptor cross-linking sites in fibrinQ65000361
Rheological properties of fibrin clots. Effects of fibrinogen concentration, Factor XIII deficiency, and Factor XIII inhibitionQ67316135
Fibrinogen-induced erythrocyte aggregation: erythrocyte-binding site in the fibrinogen moleculeQ70039500
The binding of fibrinogen and fibrinogen degradation products to the erythrocyte membrane and its relationship to haemorheologyQ71021514
Fibrinogen as a risk factor for stroke and myocardial infarctionQ71438059
Factor VII and fibrinogen levels as risk factors for venous thrombosis. A case-control study of plasma levels and DNA polymorphisms--the Leiden Thrombophilia Study (LETS)Q72841203
The effect of plasma antithrombin concentration on thrombin generation and fibrin gel structureQ72841358
Analysis of A alpha 251 fibrinogen: the alpha C domain has a role in polymerization, albeit more subtle than anticipated from the analogous proteolytic fragment XQ77501904
Increased levels of factor VIII and fibrinogen in patients with venous thrombosis are not caused by acute phase reactionsQ77871735
Impaired healing of cutaneous wounds and colonic anastomoses in mice lacking thrombin-activatable fibrinolysis inhibitorQ79105321
Functional analysis of fibrin {gamma}-chain cross-linking by activated factor XIII: determination of a cross-linking pattern that maximizes clot stiffnessQ80160260
Erythrocyte membrane sulfatide plays a crucial role in the adhesion of sickle erythrocytes to endotheliumQ83709203
Factor XIII stiffens fibrin clots by causing fiber compactionQ87628289
P4510describes a project that usesImageJQ1659584
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)1940-1948
P577publication date2015-08-31
P1433published inBloodQ885070
P859sponsorRole of coagulation factor XIII in fibrin clot structure and thrombosisQ60669183
P1476titleFactor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin α-chain crosslinking
P478volume126

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cites work (P2860)
Q58895615Advances in Clinical and Basic Science of Coagulation: Illustrated abstracts of the 9th Chapel Hill Symposium on Hemostasis
Q36088633Allosteric Inhibition of Factor XIIIa. Non-Saccharide Glycosaminoglycan Mimetics, but Not Glycosaminoglycans, Exhibit Promising Inhibition Profile.
Q90181900Assessment of whole blood coagulation with a microfluidic dielectric sensor
Q38669149Biophysical Mechanisms Mediating Fibrin Fiber Lysis.
Q90516253Blood coagulation dissected
Q50048003ClotChip: A Microfluidic Dielectric Sensor for Point-of-Care Assessment of Hemostasis
Q92249524Coagulation Factor XIIIa Inhibitor Tridegin: On the Role of Disulfide Bonds for Folding, Stability, and Function
Q45873682Factor XIII cotreatment with hemostatic agents in hemophilia A increases fibrin α-chain crosslinking.
Q92983737Factor XIII deficiency does not prevent FeCl3-induced carotid artery thrombus formation in mice
Q89893917Factor XIII in plasma, but not in platelets, mediates red blood cell retention in clots and venous thrombus size in mice
Q91659606Factor XIII topology: organization of B subunits and changes with activation studied with single-molecule atomic force microscopy
Q90639294Feeling the Force: Measurements of Platelet Contraction and Their Diagnostic Implications
Q88678011Fibrin clot strength measured by thrombelastography and outcomes after percutaneous coronary intervention
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Q58770454Fibrinogen and factor XIII: newly recognized roles in venous thrombus formation and composition
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Q88731805Immune Factors in Deep Vein Thrombosis Initiation
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Q36131278Leptospira Immunoglobulin-Like Protein B (LigB) Binds to Both the C-Terminal 23 Amino Acids of Fibrinogen αC Domain and Factor XIII: Insight into the Mechanism of LigB-Mediated Blockage of Fibrinogen α Chain Cross-Linking.
Q42261564Limiting prothrombin activation to meizothrombin is compatible with survival but significantly alters hemostasis in mice
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Q47761338When Flow Goes Slow, von Willebrand Factor Can Bind Red Blood Cells

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