N-acetylserotonin: neuroprotection, neurogenesis, and the sleepy brain

scientific article

N-acetylserotonin: neuroprotection, neurogenesis, and the sleepy brain is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1177/1073858412446634
P932PMC publication ID3422380
P698PubMed publication ID22585341
P5875ResearchGate publication ID224958067

P2093author name stringGianluca Tosini
P Michael Iuvone
Keqiang Ye
P2860cites workEfficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysisQ24537556
N-acetylserotonin activates TrkB receptor in a circadian rhythmQ24623798
Ligand efficacy and potency at recombinant human MT2 melatonin receptors: evidence for agonist activity of some mt1-antagonistsQ24672082
Sleep deprivation inhibits adult neurogenesis in the hippocampus by elevating glucocorticoidsQ24677717
Hippocampal neurogenesis in adult Old World primatesQ24684091
The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal glandQ28244766
Neurogenesis in the adult human hippocampusQ28288339
Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesisQ28567150
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligandQ28567937
The rat arylalkylamine N-acetyltransferase gene promoter. cAMP activation via a cAMP-responsive element-CCAAT complexQ28568705
Gating of the cAMP signaling cascade and melatonin synthesis by the circadian clock in mammalian retinaQ28576242
Adult neurogenesis in the mammalian central nervous systemQ29618706
Cumulative sleepiness, mood disturbance, and psychomotor vigilance performance decrements during a week of sleep restricted to 4-5 hours per nightQ29619343
Effects of poor and short sleep on glucose metabolism and obesity riskQ30409888
Time-of-day-dependent enhancement of adult neurogenesis in the hippocampusQ33388705
Period 2 regulates neural stem/progenitor cell proliferation in the adult hippocampusQ33423226
Sleep homeostasis and models of sleep regulationQ33822213
Sustained sleep fragmentation results in delayed changes in hippocampal-dependent cognitive function associated with reduced dentate gyrus neurogenesisQ34079595
Novel melatonin-based therapies: potential advances in the treatment of major depressionQ34186242
N-acetyl serotonin derivatives as potent neuroprotectants for retinasQ34254160
Restoration of brain energy metabolism as the function of sleepQ34301225
The mammalian circadian clock shop.Q34313576
'One night' sleep deprivation stimulates hippocampal neurogenesisQ34515004
N-acetylserotonin promotes hippocampal neuroprogenitor cell proliferation in sleep-deprived miceQ35008324
Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cellsQ35063857
Chronic insomnia as a risk factor for developing anxiety and depressionQ35995481
Hippocampal neurogenesis is reduced by sleep fragmentation in the adult rat.Q36106291
Antioxidant effects of N-acetylserotonin: possible mechanisms and clinical implications.Q36265321
Adult neurogenesis and functional plasticity in neuronal circuitsQ36404122
Rapid eye movement sleep deprivation contributes to reduction of neurogenesis in the hippocampal dentate gyrus of the adult rat.Q36427095
TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatmentQ37127162
Agomelatine: a novel mechanism of antidepressant action involving the melatonergic and the serotonergic system.Q37201117
Activity-dependent extrinsic regulation of adult olfactory bulb and hippocampal neurogenesisQ37312778
Melatonin modulates visual function and cell viability in the mouse retina via the MT1 melatonin receptor.Q37329500
The role of retinal photoreceptors in the regulation of circadian rhythms.Q37602589
Melatonin maintains adult hippocampal neurogenesis and cognitive functions after irradiationQ37621634
Melatonin formation in mammals: in vivo perspectivesQ37660166
Melatonin receptor agonists: new options for insomnia and depression treatmentQ37873581
Agomelatine: a narrative reviewQ37915784
Pineal Serotonin N -Acetyltransferase Activity: Abrupt Decrease in Adenosine 3′,5′-Monophosphate May Be Signal for "Turnoff"Q40120523
Effects of Total Sleep Loss on Sleep TendencyQ41703757
Sleep duration, illumination, and activity patterns in a population sample: effects of gender and ethnicityQ41735614
Circadian regulation of hippocampal long-term potentiationQ42109806
Chronic fluoxetine administration increases the serotonin N-acetyltransferase messenger RNA content in rat hippocampusQ42536216
Identification of the melatonin-binding site MT3 as the quinone reductase 2.Q42630663
Short-term sleep deprivation may alter the dynamics of hippocampal cell proliferation in adult ratsQ42930935
Melatonin promotes neurogenesis in dentate gyrus in the pinealectomized rat.Q43268626
Photic regulation of melatonin in rat retina and the role of proteasomal proteolysisQ43811327
Neuronal expression of arylalkylamine N-acetyltransferase (AANAT) mRNA in the rat brainQ43977461
Quantitative analysis of retinal ganglion cell (RGC) loss in aging DBA/2NNia glaucomatous mice: comparison with RGC loss in aging C57/BL6 miceQ44669093
Effects of exogenous melatonin on sleep: a meta-analysisQ45223376
Overlap in the distribution of TrkB immunoreactivity and retinohypothalamic tract innervation of the rat suprachiasmatic nucleusQ45274222
Sleep restriction suppresses neurogenesis induced by hippocampus-dependent learning.Q45975762
Melatonin modulates cell survival of new neurons in the hippocampus of adult mice.Q46022685
Protection of mouse photoreceptors by survival factors in retinal degenerations.Q46022707
Circadian modulation of learning and memory in fear-conditioned miceQ46571907
Sleep deprivation suppresses neurogenesis in the adult hippocampus of ratsQ46785545
Impaired hippocampal neurogenesis is involved in cognitive dysfunction induced by thiamine deficiency at early pre-pathological lesion stageQ46950822
Temporal dynamics of mouse hippocampal clock gene expression support memory processingQ47814498
Expression of brain-derived neurotrophic factor and its cognate receptor, TrkB, in the rat suprachiasmatic nucleus.Q47968660
Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferaseQ48004211
Rapid and simple measurement of serotonin N-acetyltransferase activity by liquid biphasic diffusion assayQ48089008
The expression of the melatonin synthesis enzyme: arylalkylamine N-acetyltransferase in the suprachiasmatic nucleus of rat brainQ48209663
Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cgamma signaling pathways in mouse brainQ48266494
Inhibition of hippocampal neurogenesis by sleep deprivation is independent of circadian disruption and melatonin suppressionQ48292434
Extrapineal N-acetyltransferase activity in rat brainQ48498103
Melatonin production: proteasomal proteolysis in serotonin N-acetyltransferase regulationQ48511345
Rapid Light-Induced Decrease in Pineal Serotonin N -Acetyltransferase ActivityQ48735769
TrkB-deficient mice show diminished phase shifts of the circadian activity rhythm in response to lightQ48959278
Role of brain-derived neurotrophic factor in the circadian regulation of the suprachiasmatic pacemaker by light.Q49084388
Identification and quantification of n-acetylserotonin (NAS) in the developing hippocampus of the rat.Q49096242
Selective inhibition of MAO-A but not MAO-B activity increases rat pineal melatoninQ59009915
Chronic treatment with melatonin stimulates dendrite maturation and complexity in adult hippocampal neurogenesis of miceQ61889791
Regional distribution of arylamine and arylalkylamine N-acetyltransferase activities in the rat brainQ70197580
Rat arylalkylamine N-acetyltransferase gene: upstream and intronic components of a bipartite promoterQ73431910
The effect of nifedipine, Ca(2+) antagonist, on activity of MAO inhibitors, N-acetylserotonin and melatonin in the mouse tail suspension testQ73701051
Photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cellsQ80223084
Rhythmic expression of per1 in the dentate gyrus is suppressed by corticosterone: implications for neurogenesisQ82916471
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectneurogenesisQ1456827
N-acetylserotoninQ4847704
P304page(s)645-653
P577publication date2012-05-14
P1433published inThe NeuroscientistQ7753449
P1476titleN-acetylserotonin: neuroprotection, neurogenesis, and the sleepy brain
P478volume18

Reverse relations

cites work (P2860)
Q35272964A time to remember: the role of circadian clocks in learning and memory.
Q37685742Comparison of melatonin with growth factors in promoting precursor cells proliferation in adult mouse subventricular zone
Q42703530Daily rhythms of serotonin metabolism and the expression of clock genes in suprachiasmatic nucleus of rotenone-induced Parkinson's disease male Wistar rat model and effect of melatonin administration
Q41045787Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway.
Q48164363Effects of simvastatin on the expression of inducible nitric oxide synthase and brain-derived neurotrophic factor in a lipopolysaccharide-induced rat model of Parkinson disease
Q26782989Future Directions for Pharmacotherapies for Treatment-resistant Bipolar Disorder
Q34405435Increased IL-6 trans-signaling in depression: focus on the tryptophan catabolite pathway, melatonin and neuroprogression
Q36291423Melatonin: an underappreciated player in retinal physiology and pathophysiology
Q36409142Minocycline effect on life and health span of Drosophila melanogaster
Q33820834N-acetyl-serotonin protects HepG2 cells from oxidative stress injury induced by hydrogen peroxide
Q36409066N-acetylserotonin and aging-associated cognitive impairment and depression.
Q28073105Phenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress
Q42008191Protective effect of N-acetylserotonin against acute hepatic ischemia-reperfusion injury in mice
Q28069509Recent Advances in Neurogenic Small Molecules as Innovative Treatments for Neurodegenerative Diseases
Q27012779Serotonin-kynurenine hypothesis of depression: historical overview and recent developments
Q38812610The Retina and Other Light-sensitive Ocular Clocks
Q45863218Unusual acetylation-dependent reaction cascade in the biosynthesis of the pyrroloindole drug physostigmine

Search more.