Codon 249 mutation in exon 7 of p53 gene in plasma DNA: maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area, China

scientific article

Codon 249 mutation in exon 7 of p53 gene in plasma DNA: maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area, China is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3748/WJG.V9.I4.692
P932PMC publication ID4611430
P698PubMed publication ID12679912
P5875ResearchGate publication ID284006521

P2093author name stringJian Huang
Yan Sun
Long Yu
Li-Jie Ma
Dong-Dong Lu
Xing-Hua Huang
Xi-Ran Zhang
Lu-Hong Sun
P2860cites workThe aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinomaQ24531220
Specific p53 mutations detected in plasma and tumors of hepatocellular carcinoma patients by electrospray ionization mass spectrometry.Q31983483
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancersQ34154480
Microsatellite alterations in plasma DNA of small cell lung cancer patients.Q34394739
Microsatellite alterations in serum DNA of head and neck cancer patientsQ34394745
The prognostic molecular markers in hepatocellular carcinomaQ34668320
P53 immunohistochemical scoring: an independent prognostic marker for patients after hepatocellular carcinoma resectionQ36308536
The point mutation of p53 gene exon7 in hepatocellular carcinoma from Anhui Province, a non HCC prevalent area in ChinaQ36308544
Expression of p53 and C-myc genes and its clinical relevance in the hepatocellular carcinomatous and pericarcinomatous tissuesQ36308973
Aflatoxin sufferer and p53 gene mutation in hepatocellular carcinomaQ36620217
Activation of the insulin-like growth factor II transcription by aflatoxin B1 induced p53 mutant 249 is caused by activation of transcription complexes; implications for a gain-of-function during the formation of hepatocellular carcinomaQ40860429
K-ras mutations are found in DNA extracted from the plasma of patients with colorectal cancerQ40900133
Characterization of six tumor suppressor genes and microsatellite instability in hepatocellular carcinoma in southern African blacksQ42021790
Different frequencies of p53 codon-249 hot-spot mutations in hepatocellular carcinomas in Jiang-su province of ChinaQ43510291
Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The GambiaQ43905055
Sensitivity of electrospray ionization mass spectrometry detection of codon 249 mutations in the p53 gene compared with RFLP.Q44177132
Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, People's Republic of ChinaQ44239442
p53 gene mutation in hepatocellular carcinomaQ45234400
Mutations in the p53 tumor suppressor gene in tree shrew hepatocellular carcinoma associated with hepatitis B virus infection and intake of aflatoxin B1.Q45741906
p53 mutations, chronic hepatitis B virus infection, and aflatoxin exposure in hepatocellular carcinoma in Taiwan.Q45760939
Mutations of p53 Gene in Hepatocellular Carcinoma: Roles of Hepatitis B Virus and Aflatoxin Contamination in the DietQ45881697
Monitoring of aflatoxin exposure by biomarkersQ46339249
Alterations of tumor suppressor genes and allelic losses in human hepatocellular carcinomas in ChinaQ46681132
Microsatellite analysis of plasma DNA from patients with clear cell renal carcinoma.Q52992595
Aberrations of p53 gene in human hepatocellular carcinoma from China.Q53482777
Mutational hot spot in the p53 gene in human hepatocellular carcinomasQ53499208
Presence of RNA in the nucleoprotein complex spontaneously released by human lymphocytes and frog auricles in cultureQ67376390
A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of ChinaQ72268451
Aflatoxin and liver cancerQ73401242
Mutations at codon 249 of p53 gene in human hepatocellular carcinomas from Tongan, ChinaQ73950125
[Universal presence of HBVx gene and its close association with hotspot mutation of p53 gene in hepatocellular carcinoma of prevalent area in China]Q74094349
Mutation of p53 gene in regenerative nodules in cirrhotic liverQ74485505
Characteristics of high frequency 249 codon mutation of p53 gene in hepatocellular carcinoma in prevalent area of ChinaQ77449549
[HBxAg enhanced p53 protein accumulation in hepatoma cells]Q77703971
Detection of aberrant p16 methylation in the plasma and serum of liver cancer patientsQ77804773
P433issue4
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
diagnostic markerQ129938486
P304page(s)692-695
P577publication date2003-04-01
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleCodon 249 mutation in exon 7 of p53 gene in plasma DNA: maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area, China
P478volume9

Reverse relations

cites work (P2860)
Q39724980249ser p53 mutation in the serum of black southern African patients with hepatocellular carcinoma
Q55310646A Review of Circulating Tumor DNA in Hepatobiliary Malignancies.
Q35781255DNA markers in molecular diagnostics for hepatocellular carcinoma
Q36180620Expression of PCNA and CD44mRNA in colorectal cancer with venous invasion and its relationship to liver metastasis
Q45180099Hepatocellular carcinoma and liver cirrhosis TP53 mutation analysis reflects a moderate dietary exposure to aflatoxins in Espírito Santo State, Brazil
Q38000019Infection, mutation, and cancer evolution
Q64236643It Takes a Team: A Gain-of-function Story of p53-R249S
Q40143523LAMA4, highly expressed in human hepatocellular carcinoma from Chinese patients, is a novel marker of tumor invasion and metastasis
Q38770935Liquid Biopsy and its Potential for Management of Hepatocellular Carcinoma
Q64886119Liquid biopsies for hepatocellular carcinoma.
Q91590514Liquid biopsy in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA
Q34356149Liquid biopsy: monitoring cancer-genetics in the blood
Q33680701Molecular genetics of hepatocellular neoplasia.
Q46897581Novel p53 codon 240 Ser > Thr coding region mutation in the patients of oral squamous cell carcinoma (OSCC).
Q36030952Population attributable risk of aflatoxin-related liver cancer: systematic review and meta-analysis
Q48524250Prevalence of Aflatoxin-Associated TP53R249S Mutation in Hepatocellular Carcinoma in Hispanics in South Texas
Q64272324Qidong: a crucible for studies on liver cancer etiology and prevention
Q35765804Relationship between codon 249 mutation in exon 7 of p53 gene and diagnosis of hepatocellular carcinoma
Q35623597Screen p53 mutations in hepatocellular carcinoma by FASAY: a novel splicing mutation
Q43233483Study of p53 codon 72 polymorphism and codon 249 mutations in Southern India in relation to age, alcohol drinking and smoking habits
Q52943962TP53 gene in blood plasma DNA of tumor patients.
Q54435976The prevalence of the mutation in codon 249 of the P53 gene in patients with hepatocellular carcinoma (HCC) in Turkey.

Search more.