| scholarly article | Q13442814 |
| meta-analysis | Q815382 |
| P50 | author | Yury Loika | Q88732842 |
| Yelena Kernogitski | Q88732843 | ||
| Konstantin G Arbeev | Q88732844 | ||
| Matt Duan | Q88732845 | ||
| Mikhail Kovtun | Q88732847 | ||
| P2093 | author name string | Fang Fang | |
| Liang He | |||
| Anatoliy I Yashin | |||
| Deqing Wu | |||
| Liubov Arbeeva | |||
| Svetlana V Ukraintseva | |||
| Alexander M Kulminski | |||
| Arseniy Yashkin | |||
| Irina Culminskaya | |||
| Olivia Bagley | |||
| Elena Loiko | |||
| P2860 | cites work | Lipoprotein genotype and conserved pathway for exceptional longevity in humans | Q21146060 |
| Generation and annotation of the DNA sequences of human chromosomes 2 and 4 | Q21735920 | ||
| The Sequence of the Human Genome | Q22065842 | ||
| Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study. | Q51496137 | ||
| Further delineation of the phenotype associated with heterozygous mutations in ZFHX1B. | Q51948432 | ||
| Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study. | Q53211318 | ||
| A novel interstitial deletion of 2q22.3 q23.3 in a patient with dysmorphic features, epilepsy, aganglionosis, pure red cell aplasia, and skeletal malformations. | Q53500306 | ||
| An Overview of the Health and Retirement Study | Q56060827 | ||
| The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: Design, Recruitment, and Initial Examination | Q57072992 | ||
| The miR-200 family regulates TGF-β1-induced renal tubular epithelial to mesenchymal transition through Smad pathway by targeting ZEB1 and ZEB2 expression | Q82106573 | ||
| Genetic Structures of Population Cohorts Change with Increasing Age: Implications for Genetic Analyses of Human aging and Life Span | Q94373995 | ||
| A Cross-Sectional Analysis of Late-Life Cardiovascular Factors and Their Relation to Clinically Defined Neurodegenerative Diseases | Q37083632 | ||
| Unraveling genetic origin of aging-related traits: evolving concepts | Q37102186 | ||
| Prospects for life span extension | Q37279274 | ||
| Genomewide association studies of stroke | Q37401265 | ||
| Changing course in ageing research: The healthy ageing phenotype. | Q37413744 | ||
| Age, gender, and cancer but not neurodegenerative and cardiovascular diseases strongly modulate systemic effect of the Apolipoprotein E4 allele on lifespan | Q37533800 | ||
| The effect of next-generation sequencing technology on complex trait research | Q37820686 | ||
| Franklin H. Epstein Lecture: Sirtuins, aging, and medicine | Q37886170 | ||
| Stochastic modulations of the pace and patterns of ageing: impacts on quasi-stochastic distributions of multiple geriatric pathologies | Q37941287 | ||
| The TGFbeta superfamily signaling pathway | Q38116934 | ||
| Aging and cardiovascular diseases: the role of gene-diet interactions | Q38243521 | ||
| Cytogenetic, FISH and array-CGH characterization of a complex chromosomal rearrangement carried by a mentally and language impaired patient | Q38451703 | ||
| Activins in reproductive biology and beyond. | Q38736689 | ||
| A novel long-range enhancer regulates postnatal expression of Zeb2: implications for Mowat-Wilson syndrome phenotypes | Q38988228 | ||
| Next-generation genome-wide association studies: time to focus on phenotype? | Q42932347 | ||
| Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study | Q43546731 | ||
| The Atherosclerosis Risk in Communities (ARIC) Study. Introduction and objectives of the hemostasis component | Q43823971 | ||
| A simple unified approach for estimating natural direct and indirect effects | Q44739331 | ||
| Genetic influences on age-related change in total cholesterol, low density lipoprotein-cholesterol, and triglyceride levels: longitudinal apolipoprotein E genotype effects | Q44826850 | ||
| Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. | Q47855994 | ||
| Evolution in health and medicine Sackler colloquium: Comparative genomics of autism and schizophrenia | Q22248085 | ||
| The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2 | Q24646996 | ||
| A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition | Q24649050 | ||
| PLINK: a tool set for whole-genome association and population-based linkage analyses | Q24677407 | ||
| Healthy aging: The ultimate preventative medicine | Q26770924 | ||
| Principal components analysis corrects for stratification in genome-wide association studies | Q27860975 | ||
| Scanning Human Gene Deserts for Long-Range Enhancers | Q28210571 | ||
| Meta-analysis of correlated traits via summary statistics from GWASs with an application in hypertension | Q28385677 | ||
| Common SNPs explain a large proportion of the heritability for human height | Q29547221 | ||
| Network medicine: a network-based approach to human disease | Q29547462 | ||
| Marginal structural models and causal inference in epidemiology | Q29619287 | ||
| Genes, demography, and life span: the contribution of demographic data in genetic studies on aging and longevity | Q30581631 | ||
| Genetics Analysis Workshop 16 Problem 2: the Framingham Heart Study data | Q33519288 | ||
| Application of three-level linear mixed-effects model incorporating gene-age interactions for association analysis of longitudinal family data | Q33519399 | ||
| Evolution and functional classification of vertebrate gene deserts | Q33596085 | ||
| Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals. | Q34112068 | ||
| Demography. Broken limits to life expectancy | Q34127911 | ||
| Changing concepts of morbidity and mortality in the elderly population | Q34273266 | ||
| Aging, natural death, and the compression of morbidity | Q34286032 | ||
| Genetics of the Framingham Heart Study population | Q34458072 | ||
| Integrating diverse datasets improves developmental enhancer prediction | Q35195359 | ||
| Genetics of aging, health, and survival: dynamic regulation of human longevity related traits | Q35383937 | ||
| Evolutionary molecular medicine | Q35560450 | ||
| Birth Cohort, Age, and Sex Strongly Modulate Effects of Lipid Risk Alleles Identified in Genome-Wide Association Studies | Q35752147 | ||
| Non-replication study of a genome-wide association study for hypertension and blood pressure in African Americans | Q35950904 | ||
| Genetics of longevity and aging | Q36014694 | ||
| Clues to function in gene deserts | Q36142400 | ||
| Puzzling role of genetic risk factors in human longevity: "risk alleles" as pro-longevity variants | Q36494871 | ||
| Editorial: Should We Treat Aging as a Disease? Academic, Pharmaceutical, Healthcare Policy, and Pension Fund Perspectives | Q36582506 | ||
| The role of lipid-related genes, aging-related processes, and environment in healthspan | Q36698762 | ||
| Pursuing the longevity dividend: scientific goals for an aging world | Q36994749 | ||
| Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course | Q37078854 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 11 | |
| P921 | main subject | pleiotropy | Q1134884 |
| P304 | page(s) | e1006314 | |
| P577 | publication date | 2016-11-10 | |
| P1433 | published in | PLOS Genetics | Q1893441 |
| P1476 | title | Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality | |
| P478 | volume | 12 |
| Q90479296 | Adiponectin Paradox in Alzheimer's Disease; Relevance to Amyloidogenic Evolvability? |
| Q30234468 | Cancer-Incidence, prevalence and mortality in the oldest-old. A comprehensive review |
| Q58997065 | China's oldest-old—prospects for good health in late life |
| Q58779917 | Evolvability and Neurodegenerative Disease: Antagonistic Pleiotropy Phenomena Derived from Amyloid Aggregates |
| Q90050849 | Fast Algorithms for Conducting Large-Scale GWAS of Age-at-Onset Traits Using Cox Mixed-Effects Models |
| Q46903589 | Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes |
| Q60313606 | Motor and Nonmotor Symptoms of Parkinson’s Disease: Antagonistic Pleiotropy Phenomena Derived from α-Synuclein Evolvability? |
| Q47838565 | Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive C. elegans. |
| Q64263715 | Pleiotropic Meta-Analysis of Age-Related Phenotypes Addressing Evolutionary Uncertainty in Their Molecular Mechanisms |
| Q90119400 | Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease |
| Q52332981 | Strong impact of natural-selection-free heterogeneity in genetics of age-related phenotypes. |
| Q36188425 | Suggestions from Geroscience for the Genetics of Age-Related Diseases |
| Q39206184 | The epigenetic landscape of age-related diseases: the geroscience perspective |
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