Senescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice

scientific article

Senescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.PRP.2011.01.007
P932PMC publication ID3427738
P698PubMed publication ID21353395
P5875ResearchGate publication ID50213175

P50authorMary B GoldringQ52565525
P2093author name stringSetsuro Komiya
Fumiyo Matsuda
Hirofumi Shimada
Kaneyuki Tsuchimochi
Kosei Ijiri
Harutoshi Sakakima
P2860cites workFeedback between p21 and reactive oxygen production is necessary for cell senescenceQ24299631
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4Q24322196
Sequence and expression of a cDNA encoding MyD118: a novel myeloid differentiation primary response gene induced by multiple cytokinesQ28300288
Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.Q33346368
C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57.Q33410797
GADD45beta enhances Col10a1 transcription via the MTK1/MKK3/6/p38 axis and activation of C/EBPbeta-TAD4 in terminally differentiating chondrocytesQ33707186
Adenovirus-mediated p21((WAF1/SDII/CIP1)) gene transfer induces apoptosis of human cervical cancer cell linesQ33814193
Aging, articular cartilage chondrocyte senescence and osteoarthritisQ34527279
A higher oxidative status accelerates senescence and aggravates age-dependent disorders in SAMP strains of miceQ35019552
Anabolic factors in degenerative joint diseaseQ36737807
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.Q37345878
A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiationQ37609049
cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressureQ40710279
Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.Q40767950
p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cellsQ40879237
Pathobiology of the senescence-accelerated mouse (SAM).Q41411678
Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in miceQ42173352
Telomere erosion and senescence in human articular cartilage chondrocytes.Q43562778
Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1.Q44159746
Suppression of the aging-associated decline in physical performance by a combination of resveratrol intake and habitual exercise in senescence-accelerated miceQ46335487
Senescence-accelerated mouse (SAM): a novel murine model of accelerated senescence.Q52095960
Age-associated DNA damage is accelerated in the senescence-accelerated mice.Q54036788
Immunohistochemical studies of age-associated amyloid deposition in the joint of senescence-accelerated mouse (SAM)Q54262653
Catabolic stress induces features of chondrocyte senescence through overexpression of caveolin 1: possible involvement of caveolin 1-induced down-regulation of articular chondrocytes in the pathogenesis of osteoarthritis.Q54615793
The Role of C/EBP Isoforms in the Control of Inflammatory and Native Immunity FunctionsQ57272895
p21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cellsQ64382492
p21 and parathyroid hormone-related peptide in the growth plateQ73341643
The effects of aging and treadmill running on soleus and gastrocnemius muscle morphology in the senescence-accelerated mouse (SAMP1)Q80968650
P433issue4
P921main subjectcartilageQ502730
P304page(s)225-231
P577publication date2011-02-24
P1433published inPathology, Research and PracticeQ15758752
P1476titleSenescence of chondrocytes in aging articular cartilage: GADD45β mediates p21 expression in association with C/EBPβ in senescence-accelerated mice
P478volume207