Metabolic engineering of Pichia pastoris to produce ricinoleic acid, a hydroxy fatty acid of industrial importance

scientific article

Metabolic engineering of Pichia pastoris to produce ricinoleic acid, a hydroxy fatty acid of industrial importance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1194/JLR.M060954
P932PMC publication ID4617397
P698PubMed publication ID26323290

P2093author name stringYan Chen
Xiao Qiu
Siew Hon Ng
Dauenpen Meesapyodsuk
Jianan Chen
P2860cites workEngineered high content of ricinoleic acid in fission yeast Schizosaccharomyces pombeQ83524677
Conjugated fatty acids accumulate to high levels in phospholipids of metabolically engineered soybean and Arabidopsis seedsQ83952636
The pathway of triacylglycerol synthesis through phosphatidylcholine in Arabidopsis produces a bottleneck for the accumulation of unusual fatty acids in transgenic seedsQ84461615
Engineering the push and pull of lipid biosynthesis in oleaginous yeast Yarrowia lipolytica for biofuel productionQ95423442
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Microbial production of fatty acid-derived fuels and chemicalsQ26866529
Microbial production of fatty-acid-derived fuels and chemicals from plant biomassQ29616402
Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicalsQ30658243
A high-throughput screen for genes from castor that boost hydroxy fatty acid accumulation in seed oils of transgenic ArabidopsisQ33233189
Biosynthesis of ricinoleate in castor oil.Q33639655
Type II diacylglycerol acyltransferase from Claviceps purpurea with ricinoleic acid, a hydroxyl fatty acid of industrial importance, as preferred substrateQ33649073
Castor phospholipid:diacylglycerol acyltransferase facilitates efficient metabolism of hydroxy fatty acids in transgenic Arabidopsis.Q33776544
Metabolic engineering of hydroxy fatty acid production in plants: RcDGAT2 drives dramatic increases in ricinoleate levels in seed oil.Q34013202
Improving fatty acids production by engineering dynamic pathway regulation and metabolic controlQ34025422
An oleate 12-hydroxylase from Ricinus communis L. is a fatty acyl desaturase homologQ34074625
Industrial oils from transgenic plants.Q35095668
Engineering oilseeds for sustainable production of industrial and nutritional feedstocks: solving bottlenecks in fatty acid flux.Q36792073
The production of unusual fatty acids in transgenic plants.Q36808065
Identification of a pair of phospholipid:diacylglycerol acyltransferases from developing flax (Linum usitatissimum L.) seed catalyzing the selective production of trilinoleninQ37099795
A peroxygenase pathway involved in the biosynthesis of epoxy fatty acids in oat.Q38333146
Heterologous expression of a fatty acid hydroxylase gene in developing seeds of Arabidopsis thalianaQ38519306
A small phospholipase A2-α from castor catalyzes the removal of hydroxy fatty acids from phosphatidylcholine in transgenic Arabidopsis seeds.Q41456261
Transgenic expression of a delta 12-epoxygenase gene in Arabidopsis seeds inhibits accumulation of linoleic acidQ43603320
Accumulation of ricinoleic, lesquerolic, and densipolic acids in seeds of transgenic Arabidopsis plants that express a fatty acyl hydroxylase cDNA from castor beanQ46170266
An oleate hydroxylase from the fungus Claviceps purpurea: cloning, functional analysis, and expression in ArabidopsisQ46604368
A bifunctional oleate 12-hydroxylase: desaturase from Lesquerella fendleriQ47780055
Metabolic engineering for ricinoleic acid production in the oleaginous yeast Yarrowia lipolyticaQ48037069
Storage lipid synthesis is non-essential in yeast.Q52544739
Three diacylglycerol acyltransferases contribute to oil biosynthesis and normal growth in Yarrowia lipolytica.Q52619745
Modular optimization of multi-gene pathways for fatty acids production in E. coli.Q54318153
A fatty acid condensing enzyme from Physaria fendleri increases hydroxy fatty acid accumulation in transgenic oilseeds of Camelina sativaQ59943306
P433issue11
P921main subjectfatty acidQ61476
Pichia pastorisQ148697
P304page(s)2102-2109
P577publication date2015-08-31
P1433published inJournal of Lipid ResearchQ6295449
P1476titleMetabolic engineering of Pichia pastoris to produce ricinoleic acid, a hydroxy fatty acid of industrial importance
P478volume56

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cites work (P2860)
Q92755065CRISPR-Cas9-mediated genomic multiloci integration in Pichia pastoris
Q47255058Heterologous Protein Expression in Pichia pastoris: Latest Research Progress and Applications
Q50315238Metabolic Engineering for Enhanced Medium Chain Omega Hydroxy Fatty Acid Production in Escherichia coli
Q47666354Metabolic engineering of Schizosaccharomyces pombe to produce punicic acid, a conjugated fatty acid with nutraceutic properties
Q28830099Novel homologous lactate transporter improves L-lactic acid production from glycerol in recombinant strains of Pichia pastoris
Q37405748Production of ricinoleic acid-containing monoestolide triacylglycerides in an oleaginous diatom, Chaetoceros gracilis
Q38774835Road to the future of systems biotechnology: CRISPR-Cas-mediated metabolic engineering for recombinant protein production
Q38846910Three, two, one yeast fatty acid desaturases: regulation and function.

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