Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment

scientific article

Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00262-015-1749-6
P932PMC publication ID4618101
P698PubMed publication ID26250807

P50authorJaime ModianoQ42696815
Jakub TolarQ34445573
P2093author name stringJerome Schaack
Ron T McElmurry
Timothy D O'Brien
Colleen L Forster
Donald Bellgrau
Beth A Lindborg
Edward A Zamora
Mitzi Lewellen
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Mesenchymal stem cells alleviate experimental asthma by inducing polarization of alveolar macrophagesQ45848683
Selected Stro-1-enriched bone marrow stromal cells display a major suppressive effect on lymphocyte proliferation.Q45896896
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Human mesenchymal stromal cells modulate T-cell responses through TNF-α-mediated activation of NF-κBQ60394821
Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentationQ61976669
Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animalsQ62083511
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T cell exclusion, immune privilege, and the tumor microenvironmentQ28259872
Mouse bone marrow-derived mesenchymal stromal cells turn activated macrophages into a regulatory-like profileQ33532608
Gene transfer of Fas ligand induces tumor regression in vivoQ33731661
Homologous mesenchymal stem cells promote the emergence and growth of pulmonary metastases of the rat osteosarcoma cell line UMR-106Q33778236
Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imagingQ34164696
Mesenchymal stem cells ameliorate rhabdomyolysis-induced acute kidney injury via the activation of M2 macrophagesQ34502380
Arginase II expressed in cancer-associated fibroblasts indicates tissue hypoxia and predicts poor outcome in patients with pancreatic cancerQ34592559
Fas-ligand--iron fist or Achilles' heel?Q34623195
A cytokine-mediated link between innate immunity, inflammation, and cancerQ34625152
Interleukin-8 promotes canine hemangiosarcoma growth by regulating the tumor microenvironment.Q34633575
Mesenchymal-stem-cell-induced immunoregulation involves FAS-ligand-/FAS-mediated T cell apoptosisQ35946990
Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoringQ36048767
The IL-6-STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progressionQ36179636
The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligandQ36367323
CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFαQ36456715
Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancerQ36460454
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Adenoviral-mediated gene transfer in lymphocytes.Q36641367
MHC-dependent desensitization of intrinsic anti-self reactivityQ36978119
Type I interferon as a stimulus for cross-primingQ37027815
Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10.Q37241672
Immunosuppressive effect of bone marrow-derived mesenchymal stem cells in inflammatory microenvironment favours the growth of B16 melanoma cellsQ37294845
Bone marrow-derived mesenchymal stem cells and the tumor microenvironmentQ37735741
Chemoimmunotherapy: reengineering tumor immunityQ38079749
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Mesenchymal stem cells use IDO to regulate immunity in tumor microenvironmentQ38363548
P433issue11
P304page(s)1449-1460
P577publication date2015-08-07
P1433published inCancer Immunology, ImmunotherapyQ5031409
P1476titleMesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment
P478volume64