Efficacy and Safety of Anti-Interleukin-5 Therapy in Patients with Asthma: A Systematic Review and Meta-Analysis

scientific article

Efficacy and Safety of Anti-Interleukin-5 Therapy in Patients with Asthma: A Systematic Review and Meta-Analysis is …
instance of (P31):
meta-analysisQ815382
review articleQ7318358
scholarly articleQ13442814

External links are
P819ADS bibcode2016PLoSO..1166833W
P356DOI10.1371/JOURNAL.PONE.0166833
P8608Fatcat IDrelease_gtalzrmwzfd23jbvmr7zxwztii
P932PMC publication ID5119789
P698PubMed publication ID27875559

P2093author name stringTing Liu
Hui Mao
Zhu Lan
Fa-Ping Wang
Su-Yun Li
P2860cites workEffect of SCH55700, a humanized anti-human interleukin-5 antibody, in severe persistent asthma: a pilot study.Q49032278
Benralizumab, an anti-interleukin 5 receptor α monoclonal antibody, versus placebo for uncontrolled eosinophilic asthma: a phase 2b randomised dose-ranging studyQ51026334
Determining a minimal important change in a disease-specific Quality of Life QuestionnaireQ51136958
A Phase 2a Study of Benralizumab for Patients with Eosinophilic Asthma in South Korea and JapanQ51531321
Reslizumab for Inadequately Controlled Asthma With Elevated Blood Eosinophil Levels: A Randomized Phase 3 StudyQ51534265
Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthmaQ51699006
A study to evaluate safety and efficacy of mepolizumab in patients with moderate persistent asthmaQ53176283
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.Q55034563
A re-analysis of the Cochrane Library data: the dangers of unobserved heterogeneity in meta-analysesQ21559581
Mepolizumab versus placebo for asthmaQ24186306
Bronchial thermoplasty for moderate or severe persistent asthma in adultsQ24198119
Purified interleukin 5 supports the terminal differentiation and proliferation of murine eosinophilic precursorsQ24682536
The past, present, and future of monoclonal antibodies to IL-5 and eosinophilic asthma: a reviewQ26775861
Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung diseaseQ26786229
Emerging therapeutic options for the treatment of patients with symptomatic asthmaQ26800791
Quantifying heterogeneity in a meta-analysisQ27860672
Reslizumab for Poorly Controlled, Eosinophilic AsthmaQ29040017
The global burden of asthma: executive summary of the GINA Dissemination Committee reportQ29614904
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophiliaQ34230967
Global strategy for asthma management and prevention: GINA executive summary.Q34731997
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmaticsQ36001230
A simulation study comparing properties of heterogeneity measures in meta-analysesQ36601029
Uncertainty in heterogeneity estimates in meta-analysesQ36987539
IL-5 and eosinophilia.Q37176808
Mepolizumab and exacerbations of refractory eosinophilic asthmaQ37711391
Anti-interleukin-5 therapy in severe asthmaQ38133493
Update on reslizumab for eosinophilic asthmaQ38587334
Targeting the interleukin pathway in the treatment of asthmaQ38588854
Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma.Q38616563
A randomized trial of benralizumab, an antiinterleukin 5 receptor α monoclonal antibody, after acute asthmaQ39090432
Efficacy of Anti-Interleukin-5 Therapy with Mepolizumab in Patients with Asthma: A Meta-Analysis of Randomized Placebo-Controlled TrialsQ39353794
Benralizumab, an anti-interleukin-5 receptor α monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trialQ39408906
Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studiesQ39768068
Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trialsQ41452053
Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma: Effects Across a Broad Range of Eosinophil CountsQ45294119
Efficacy and safety of benralizumab for patients with severe asthma uncontrolled with high-dosage inhaled corticosteroids and long-acting β2-agonists (SIROCCO): a randomised, multicentre, placebo-controlled phase 3 trialQ45297326
Mepolizumab for prednisone-dependent asthma with sputum eosinophiliaQ46098864
Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trialQ47249808
Monoclonal anti-interleukin-5 treatment suppresses eosinophil but not T-cell functionsQ47890299
Mepolizumab treatment in patients with severe eosinophilic asthmaQ48065984
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectasthmaQ35869
peptideQ172847
globulinsQ321710
monoclonal antibodyQ422248
blood proteinsQ425056
meta-analysisQ815382
systematic reviewQ1504425
quality of lifeQ13100823
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)e0166833
P577publication date2016-11-22
P1433published inPLOS OneQ564954
P1476titleEfficacy and Safety of Anti-Interleukin-5 Therapy in Patients with Asthma: A Systematic Review and Meta-Analysis
P478volume11

Reverse relations

cites work (P2860)
Q92401162Adverse events of benralizumab in moderate to severe eosinophilic asthma: A meta-analysis
Q47551081Anti-IL5 therapies for asthma.
Q92756237Asthma and Chronic Rhinosinusitis: Diagnosis and Medical Management
Q39226704Clinical management of severe therapy-resistant asthma
Q49722360Cutaneous Manifestations of Reactions to Biologics
Q64113098Efficacy and steroid-sparing effect of benralizumab: has it an advantage over its competitors?
Q52646644Efficacy and tolerability of short-term duloxetine treatment in adults with generalized anxiety disorder: A meta-analysis.
Q55082118Health care resource utilization and characteristics of patients with eosinophilic asthma in secondary health care in Finland.
Q47555559Pharmacokinetic/pharmacodynamic drug evaluation of benralizumab for the treatment of asthma
Q38661881Reslizumab in the treatment of inadequately controlled asthma in adults and adolescents with elevated blood eosinophils: clinical trial evidence and future prospects
Q58778332Resolution of chronic inflammatory disease: universal and tissue-specific concepts
Q42370782Short-term efficacy and tolerability of venlafaxine extended release in adults with generalized anxiety disorder without depression: A meta-analysis
Q52571066Targeting the Interleukin-5 Pathway for Treatment of Eosinophilic Conditions Other than Asthma

Search more.