| scholarly article | Q13442814 |
| P50 | author | Dorothy Hatsukami | Q87445426 |
| P2093 | author name string | David L Ashley | |
| Kenneth A Perkins | |||
| Neal L Benowitz | |||
| Jack E Henningfield | |||
| Cathy L Backinger | |||
| Mitch Zeller | |||
| Mark G Lesage | |||
| P2860 | cites work | Deprivation state but not nicotine content of the cigarette affects responding by smokers on a progressive ratio task | Q48706612 |
| Metabolites of nicotine in rat brain after peripheral nicotine administration. Cotinine, nornicotine, and norcotinine | Q48819464 | ||
| Discriminative stimulus properties of nicotine: further evidence for mediation at a cholinergic receptor | Q48830377 | ||
| Genotype regulates the development of tolerance to ethanol and cross-tolerance to nicotine | Q48848346 | ||
| Intravenous self-administration of acetaldehyde in the rat as a function of schedule, food deprivation and photoperiod | Q49076876 | ||
| Nicotine discrimination and self-administration in humans as a function of smoking status. | Q50946191 | ||
| Dissociating nicotine and nonnicotine components of cigarette smoking. | Q51072196 | ||
| Long-term potentiation of excitatory inputs to brain reward areas by nicotine. | Q51381056 | ||
| Cocaine use can increase cigarette smoking: evidence from laboratory and naturalistic settings. | Q51538418 | ||
| Acquisition of nicotine self-administration in adolescent rats given prolonged access to the drug. | Q51798710 | ||
| Nicotine self-administration, extinction responding and reinstatement in adolescent and adult male rats: evidence against a biological vulnerability to nicotine addiction during adolescence. | Q51903584 | ||
| Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats. | Q51996777 | ||
| Immediate and long-term behavioral effects of a single nicotine injection in adolescent and adult rats. | Q52002283 | ||
| Association of OPRM1 A118G variant with the relative reinforcing value of nicotine. | Q52007326 | ||
| Periadolescent and adult rats respond differently in tests measuring the rewarding and aversive effects of nicotine. | Q52021597 | ||
| Sex differences in the acute effects of cigarette smoking on the reinforcing value of alcohol. | Q52168221 | ||
| Nornicotine is self-administered intravenously by rats. | Q52172593 | ||
| Comparing the reinforcing efficacy of nicotine containing and de-nicotinized cigarettes: a behavioral economic analysis. | Q52172650 | ||
| Chronic caffeine exposure potentiates nicotine self-administration in rats. | Q52177418 | ||
| Blockade of nicotine self-administration with nicotinic antagonists in rats. | Q52177843 | ||
| Nicotine-containing versus de-nicotinized cigarettes: effects on craving and withdrawal. | Q52194847 | ||
| Nicotine self-administration in rats: strain and nicotine pre-exposure effects on acquisition. | Q52197424 | ||
| Dissociating the nicotine and airway sensory effects of smoking. | Q52202821 | ||
| Nicotine and some related compounds: effects on schedule-controlled behaviour and discriminative properties in rats. | Q52248886 | ||
| Smoking without nicotine delivery decreases withdrawal in 12-hour abstinent smokers. | Q52271610 | ||
| Pharmacodynamic effects of new de-nicotinized cigarettes. | Q52279106 | ||
| Nicotine is more reinforcing in smokers with a past history of alcoholism than in smokers without this history. | Q52279175 | ||
| Symptoms of tobacco dependence after brief intermittent use: the Development and Assessment of Nicotine Dependence in Youth-2 study. | Q52291405 | ||
| Characterization of the receptor mediating the nicotine discriminative stimulus. | Q52295939 | ||
| Inhibition of cytochrome P450 2A6 increases nicotine's oral bioavailability and decreases smoking | Q59488301 | ||
| Tobacco‐specific nitrosamines in new tobacco products | Q61207149 | ||
| Smoking cessation in young adults: age at initiation of cigarette smoking and other suspected influences | Q71086077 | ||
| Nicotine self-administration in rats | Q71134166 | ||
| Desensitization of nicotinic agonist-induced [3H]gamma-aminobutyric acid release from mouse brain synaptosomes is produced by subactivating concentrations of agonists | Q73192618 | ||
| Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2'-(14)C]nicotine | Q73201572 | ||
| Effects of varying ethanol dose on cigarette consumption in healthy normal volunteers | Q73553776 | ||
| Age of smoking initiation: implications for quitting | Q77629415 | ||
| New lower nicotine cigarettes can produce compensatory smoking and increased carbon monoxide exposure | Q80163465 | ||
| The scientific basis of tobacco product regulation | Q81093611 | ||
| THE ROLE OF NICOTINE IN THE CIGARETTE HABIT | Q81125472 | ||
| Regulations restricting the sale and distribution of cigarettes and smokeless tobacco to protect children and adolescents. Final rule | Q84041142 | ||
| Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes | Q24551187 | ||
| Milestones in the natural course of onset of cigarette use among adolescents | Q24553823 | ||
| Transient behavioral sensitization to nicotine becomes long-lasting with monoamine oxidases inhibitors | Q28181027 | ||
| Monoamine oxidase inhibition dramatically increases the motivation to self-administer nicotine in rats | Q28273463 | ||
| Role of acetaldehyde in tobacco smoke addiction | Q28294694 | ||
| Sex and ovarian hormones influence vulnerability and motivation for nicotine during adolescence in rats | Q30434367 | ||
| The genetics of nicotine dependence | Q30439784 | ||
| Variability in initial nicotine sensitivity due to sex, history of other drug use, and parental smoking | Q30484284 | ||
| Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers | Q30486679 | ||
| Subjective and reinforcing effects of smoking during negative mood induction | Q30541262 | ||
| Development of symptoms of tobacco dependence in youths: 30 month follow up data from the DANDY study. | Q30717075 | ||
| Progressive commercial cigarette yield reduction: biochemical exposure and behavioral assessment | Q33575373 | ||
| Monoamine oxidase and cigarette smoking. | Q33845951 | ||
| Individual differences in smoking reward from de-nicotinized cigarettes | Q34279993 | ||
| A consideration of the role of gas/particle partitioning in the deposition of nicotine and other tobacco smoke compounds in the respiratory tract | Q34442395 | ||
| Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction | Q34756369 | ||
| Toward a comprehensive long term nicotine policy. | Q35539423 | ||
| Placebo effects of tobacco smoking and other nicotine intake | Q35567789 | ||
| Reducing the addictiveness of cigarettes. Council on Scientific Affairs, American Medical Association | Q35573356 | ||
| Smokeless tobacco use: harm reduction or induction approach? | Q35650428 | ||
| Low dose nicotine treatment during early adolescence increases subsequent cocaine reward | Q35740825 | ||
| Tobacco dependence and withdrawal: science base, challenges and opportunities for pharmacotherapy | Q35964545 | ||
| Nicotine self-administration in rats | Q36004229 | ||
| Adolescent vs. adult-onset nicotine self-administration in male rats: duration of effect and differential nicotinic receptor correlates | Q36015224 | ||
| Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation. | Q36047601 | ||
| Assessing internal tobacco industry knowledge of the neurobiology of tobacco dependence | Q36084935 | ||
| On the development of nicotine dependence in adolescence | Q36092293 | ||
| Medication screening for smoking cessation: a proposal for new methodologies | Q36257654 | ||
| Sex differences in the contribution of nicotine and nonpharmacological stimuli to nicotine self-administration in rats. | Q45245208 | ||
| Reduced nicotine reward in obesity: cross-comparison in human and mouse | Q45272359 | ||
| Risk factors and their effects on the dynamic process of smoking relapse among veteran smokers | Q45333006 | ||
| The addition of five minor tobacco alkaloids increases nicotine-induced hyperactivity, sensitization and intravenous self-administration in rats. | Q46051348 | ||
| Establishing a nicotine threshold for addiction. The implications for tobacco regulation | Q46058830 | ||
| Nicotine intake and dose response when smoking reduced-nicotine content cigarettes | Q46074167 | ||
| Tranylcypromine enhancement of nicotine self-administration. | Q46182407 | ||
| A randomized trial of nicotine replacement therapy in combination with reduced-nicotine cigarettes for smoking cessation | Q46482057 | ||
| Placebo cigarettes in a spaced smoking paradigm | Q46490694 | ||
| Initial nicotine sensitivity in humans as a function of impulsivity | Q46499261 | ||
| Methylphenidate increases cigarette smoking | Q46571119 | ||
| Sex differences in the influence of nicotine dose instructions on the reinforcing and self-reported rewarding effects of smoking | Q46630826 | ||
| Intravenous nicotine self-administration in rats: effects of mecamylamine, hexamethonium and naloxone | Q46641531 | ||
| Interactions between age and the aversive effects of nicotine withdrawal under mecamylamine-precipitated and spontaneous conditions in male Wistar rats. | Q46666600 | ||
| Mood influences on acute smoking responses are independent of nicotine intake and dose expectancy | Q46759995 | ||
| Acetaldehyde, a major constituent of tobacco smoke, enhances behavioral, endocrine, and neuronal responses to nicotine in adolescent and adult rats | Q46842997 | ||
| Age differences in the spontaneous acquisition of nicotine self-administration in male Wistar and Long-Evans rats | Q46880882 | ||
| Nicotine and carcinogen exposure with smoking of progressively reduced nicotine content cigarette | Q46897472 | ||
| Treating smokers before the quit date: can nicotine patches and denicotinized cigarettes reduce cravings? | Q46917588 | ||
| Precessation treatment with nicotine skin patch facilitates smoking cessation | Q46960275 | ||
| The monoamine oxidase inhibitor phenelzine enhances the discriminative stimulus effect of nicotine in rats | Q46970124 | ||
| Clozapine attenuates the discriminative stimulus properties of (-)-nicotine | Q48139148 | ||
| S(-)-nornicotine increases dopamine release in a calcium-dependent manner from superfused rat striatal slices | Q48271219 | ||
| Smoking in the absence of nicotine: behavioral, subjective and physiological effects over 11 days | Q48418098 | ||
| Nicotine self-administration in rats: estrous cycle effects, sex differences and nicotinic receptor binding. | Q48700414 | ||
| Nicotine addiction and comorbidity with alcohol abuse and mental illness | Q36298360 | ||
| Guidelines on nicotine dose selection for in vivo research. | Q36560437 | ||
| It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood | Q36666651 | ||
| Risk factors for tobacco dependence in adolescent smokers. | Q36930336 | ||
| Nicotine metabolism in three ethnic/racial groups with different risks of lung cancer | Q37008114 | ||
| Rodent models of nicotine reward: what do they tell us about tobacco abuse in humans? | Q37106501 | ||
| Methylphenidate enhances the abuse-related behavioral effects of nicotine in rats: intravenous self-administration, drug discrimination, and locomotor cross-sensitization | Q37147049 | ||
| Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood | Q37280300 | ||
| Prolonged exposure to denicotinized cigarettes with or without transdermal nicotine. | Q37304946 | ||
| Sex differences in nicotine reinforcement and reward: influences on the persistence of tobacco smoking. | Q37327406 | ||
| Approaches, challenges, and experience in assessing free nicotine | Q37382334 | ||
| Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors | Q37412735 | ||
| Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette | Q37412757 | ||
| Pharmacological and psychological determinants of smoking. A New York University honors program lecture | Q39177904 | ||
| A multi-dimensional examination of the positive reinforcing properties of acetaldehyde | Q39824051 | ||
| Linking quantity and frequency profiles of cigarette smoking to the presence of nicotine dependence symptoms among adolescent smokers: findings from the 2004 National Youth Tobacco Survey | Q39999342 | ||
| The role of CYP2A6 in the emergence of nicotine dependence in adolescents | Q40266111 | ||
| Nicotine delivery kinetics and abuse liability | Q40782278 | ||
| Cigarette smoking during anxiety-provoking and monotonous tasks | Q41591753 | ||
| Smokeless tobacco: an addicting drug. | Q41730566 | ||
| Eliminating nicotine in cigarettes | Q43026647 | ||
| Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans | Q43459056 | ||
| Accumulation of nicotine and its metabolites in rat brain after intermittent or continuous peripheral administration of [2'-(14)C]nicotine | Q43575389 | ||
| Threshold doses for nicotine discrimination in smokers and non-smokers | Q43636193 | ||
| Withdrawal-suppressing effects of a novel smoking system: comparison with own brand, not own brand, and de-nicotinized cigarettes | Q43638190 | ||
| Intravenous self-administration of ethanol and acetaldehyde by rats | Q43655348 | ||
| Sensitivity of nicotine-containing and de-nicotinized cigarette consumption to alternative non-drug reinforcement: a behavioral economic analysis | Q43731262 | ||
| Rat strain differences in nicotine self-administration using an unlimited access paradigm | Q43906345 | ||
| Peculiar vulnerability to nicotine oral self-administration in mice during early adolescence | Q44047422 | ||
| Nicotine-induced conditioned place preference in adolescent and adult rats | Q44126618 | ||
| Effects of cigarette nicotine content and smoking pace on subsequent craving and smoking | Q44206077 | ||
| Nicotine maintains robust self-administration in rats on a limited-access schedule | Q44290531 | ||
| Evaluating acute effects of potential reduced-exposure products for smokers: clinical laboratory methodology | Q44305935 | ||
| Age-dependent differences in nicotine reward and withdrawal in female mice | Q44353544 | ||
| Does menthol enhance the addictiveness of cigarettes? An agenda for research | Q44440063 | ||
| Adolescent-onset nicotine self-administration modeled in female rats | Q44452279 | ||
| Nicotine-dependence symptoms are associated with smoking frequency in adolescents | Q44595078 | ||
| Pharmacologic and sensorimotor components of satiation in cigarette smoking | Q44638852 | ||
| Age-dependent effects of nicotine on locomotor activity and conditioned place preference in rats | Q44739804 | ||
| Acetaldehyde increases dopaminergic neuronal activity in the VTA. | Q44770261 | ||
| Nicotine serves as an effective reinforcer of intravenous drug-taking behavior in human cigarette smokers | Q44784239 | ||
| Isolation and characterization of a monoamine oxidase inhibitor from tobacco leaves | Q44867929 | ||
| Nicotine dependence and reward differ between adolescent and adult male mice | Q44928727 | ||
| Ammonia and other chemical base tobacco additives and cigarette nicotine delivery: issues and research needs | Q44941652 | ||
| The AMA proposal to mandate nicotine reduction in cigarettes: a simulation of the population health impacts | Q45144085 | ||
| P433 | issue | 5 | |
| P921 | main subject | nicotine | Q12144 |
| P304 | page(s) | e1-10 | |
| P577 | publication date | 2010-10-01 | |
| P1433 | published in | Tobacco Control | Q15766348 |
| P1476 | title | Nicotine reduction revisited: science and future directions | |
| P478 | volume | 19 |
| Q27335497 | A Two-Day Continuous Nicotine Infusion Is Sufficient to Demonstrate Nicotine Withdrawal in Rats as Measured Using Intracranial Self-Stimulation |
| Q36696626 | A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats |
| Q35110020 | Animal models to assess the abuse liability of tobacco products: effects of smokeless tobacco extracts on intracranial self-stimulation. |
| Q34554766 | Animal research on nicotine reduction: Current evidence and research gaps |
| Q33965983 | Cigarette smoke, bacteria, mold, microbial toxins, and chronic lung inflammation |
| Q36868963 | Clinical strategies to enhance the efficacy of nicotine replacement therapy for smoking cessation: a review of the literature. |
| Q45418024 | Commentary on Etter & Bullen (2011): could E-cigs become the ultimate nicotine maintenance device? |
| Q37349081 | Comparative risk assessment of tobacco smoke constituents using the margin of exposure approach: the neglected contribution of nicotine |
| Q57036602 | Concentrations of nicotine, nitrosamines, and humectants in legal and illegal cigarettes in Mexico |
| Q45070774 | Consortium on Methods Evaluating Tobacco: Research Tools to Inform FDA Regulation of Snus. |
| Q50927558 | Corrective Taxes and Cigarette Characteristics. |
| Q35997407 | Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats |
| Q36823255 | Dose-response effects of spectrum research cigarettes |
| Q45981734 | Effects of 6-Week Use of Reduced-Nicotine Content Cigarettes in Smokers With and Without Elevated Depressive Symptoms. |
| Q42418777 | Effects of Monoamine Oxidase Inhibition on the Reinforcing Properties of Low-Dose Nicotine |
| Q35875970 | Effects of nicotine and minor tobacco alkaloids on intracranial-self-stimulation in rats. |
| Q36786040 | Ending tobacco-caused mortality and morbidity: the case for performance standards for tobacco products |
| Q46416161 | Estimations and predictors of non-compliance in switchers to reduced nicotine content cigarettes. |
| Q37215565 | Gradual and immediate nicotine reduction result in similar low-dose nicotine self-administration |
| Q36667391 | Greater reductions in nicotine exposure while smoking very low nicotine content cigarettes predict smoking cessation |
| Q85102973 | Imagining things otherwise: new endgame ideas for tobacco control |
| Q36727831 | Impact of tobacco regulation on animal research: new perspectives and opportunities |
| Q38779511 | Low nicotine content descriptors reduce perceived health risks and positive cigarette ratings in participants using very low nicotine content cigarettes |
| Q89259971 | Nicotine Reduction Strategy: State of the science and challenges to tobacco control policy and FDA tobacco product regulation |
| Q35657833 | Nicotine reduction as an increase in the unit price of cigarettes: a behavioral economics approach |
| Q36823218 | Nicotine reduction: strategic research plan |
| Q46593672 | Nicotinic effects of tobacco smoke constituents in nonhuman primates |
| Q30380558 | Predicted Impact of Nicotine Reduction on Smokers with Affective Disorders. |
| Q27312260 | Predictors of the nicotine reinforcement threshold, compensation, and elasticity of demand in a rodent model of nicotine reduction policy |
| Q53632915 | Preliminary test of cigarette nicotine discrimination threshold in non-dependent versus dependent smokers. |
| Q52300452 | Public attitudes regarding banning of cigarettes and regulation of nicotine. |
| Q85910728 | Public support for mandated nicotine reduction in cigarettes |
| Q41658014 | Reduced Nicotine Content Expectancies Affect Initial Responses to Smoking |
| Q47233701 | Reduced nicotine content cigarette advertising: How false beliefs and subjective ratings affect smoking behavior |
| Q36927046 | Reduced nicotine content cigarettes and nicotine patch |
| Q47957996 | Reduced nicotine content cigarettes and use of alternative nicotine products: exploratory trial. |
| Q34621879 | Reduced nicotine product standards for combustible tobacco: building an empirical basis for effective regulation |
| Q36786014 | Reducing the nicotine content to make cigarettes less addictive |
| Q36956964 | Research required for the effective implementation of the framework convention on tobacco control, articles 9 and 10. |
| Q38521957 | Review of hookah tobacco smoking among college students: policy implications and research recommendations |
| Q34487271 | Scientific overview: 2013 BBC plenary symposium on tobacco addiction |
| Q36471948 | Separate and combined effects of very low nicotine cigarettes and nicotine replacement in smokers with schizophrenia and controls |
| Q35588184 | Sex differences in acute relief of abstinence-induced withdrawal and negative affect due to nicotine content in cigarettes |
| Q37519158 | Sex differences in nicotine self-administration in rats during progressive unit dose reduction: implications for nicotine regulation policy |
| Q33855129 | Sex differences in response to reduced nicotine content cigarettes. |
| Q35947187 | Smoking behavior and exposure to tobacco toxicants during 6 months of smoking progressively reduced nicotine content cigarettes |
| Q44165205 | Standing on the threshold of change |
| Q57171561 | Status and Future Directions of Preclinical Behavioral Pharmacology in Tobacco Regulatory Science |
| Q47989082 | The combined effect of very low nicotine content cigarettes, used as an adjunct to usual Quitline care (nicotine replacement therapy and behavioural support), on smoking cessation: a randomized controlled trial |
| Q41025969 | The effects of nicotine and non-nicotine smoking factors on working memory and associated brain function |
| Q33949792 | The predicted impact of reducing the nicotine content in cigarettes on alcohol use |
| Q36164835 | The reinforcement threshold for nicotine as a target for tobacco control |
| Q37282614 | The tobacco endgame: a qualitative review and synthesis |
| Q50455473 | Threshold dose for behavioral discrimination of cigarette nicotine content in menthol vs. non-menthol smokers |
| Q36917735 | Threshold dose for discrimination of nicotine via cigarette smoking |
| Q35624469 | Tobacco and nicotine product testing |
| Q36786064 | Tobacco endgames: what they are and are not, issues for tobacco control strategic planning and a possible US scenario |
| Q35562592 | Transgenic and mutation-based suppression of a berberine bridge enzyme-like (BBL) gene family reduces alkaloid content in field-grown tobacco |
| Q37242430 | Transient compensatory smoking in response to placebo cigarettes |
| Q28708837 | Why ban the sale of cigarettes? The case for abolition |
| Q55033207 | e-Cigarette awareness, use, and harm perceptions in US adults. |
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