Evidence from clinical and animal model studies of the long-term and transgenerational impact of stress on DNA methylation

scientific article

Evidence from clinical and animal model studies of the long-term and transgenerational impact of stress on DNA methylation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.SEMCDB.2015.04.004
P932PMC publication ID4618788
P698PubMed publication ID25917771

P2093author name stringTania L Roth
Jennifer Blaze
P2860cites workTransgenerational Epigenetic Inheritance: Prevalence, Mechanisms, and Implications for the Study of Heredity and EvolutionQ22066105
Lasting epigenetic influence of early-life adversity on the BDNF geneQ24600763
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuseQ24602512
Human DNA methylomes at base resolution show widespread epigenomic differencesQ24633677
Epigenetic mechanisms in learning and memoryQ40610820
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosineQ41938716
DNA methylation in vulnerability to post-traumatic stress in rats: evidence for the role of the post-synaptic density protein Dlgap2.Q43269050
Lower methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of veterans with posttraumatic stress disorderQ45329002
Intensity matters: brain, behaviour and the epigenome of prenatally stressed ratsQ46521085
Differential glucocorticoid receptor exon 1(B), 1(C), and 1(H) expression and methylation in suicide completers with a history of childhood abuseQ46838358
Prereproductive stress to female rats alters corticotropin releasing factor type 1 expression in ova and behavior and brain corticotropin releasing factor type 1 expression in offspringQ48014425
Investigating the influence of maternal cortisol and emotional state during pregnancy on the DNA methylation status of the glucocorticoid receptor gene (NR3C1) promoter region in cord blood.Q48031836
Epigenetic transmission of the impact of early stress across generations.Q48105291
Paternal stress prior to conception alters DNA methylation and behaviour of developing rat offspringQ48109582
Borderline personality disorder and childhood maltreatment: a genome-wide methylation analysisQ48130138
Stress during development alters dendritic morphology in the nucleus accumbens and prefrontal cortexQ48542545
Prenatal bystander stress induces neuroanatomical changes in the prefrontal cortex and hippocampus of developing rat offspringQ48963121
Hydroxymethylation and DNA methylation profiles in the prefrontal cortex of the non-human primate rhesus macaque and the impact of maternal deprivation on hydroxymethylation.Q50675701
'Lamarckian' mechanisms in darwinian evolution.Q52188527
Epigenetic transgenerational actions of endocrine disruptors.Q52570812
Are children of Holocaust survivors less well-adapted? A meta-analytic investigation of secondary traumatizationQ79221228
Transgenerational inheritance of induced changes in the epigenetic state of chromatin in plantsQ84971448
DNA modifications: Another stable base in DNAQ86028009
Adult glucocorticoid exposure leads to transcriptional and DNA methylation changes in nuclear steroid receptors in the hippocampus and kidney of mouse male offspringQ87145411
MeCP2, a key contributor to neurological disease, activates and represses transcriptionQ24647533
Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesisQ24651301
Transposable elements: targets for early nutritional effects on epigenetic gene regulationQ24681243
Broad epigenetic signature of maternal care in the brain of adult ratsQ27314001
Epigenetic programming by maternal behaviorQ27860466
Dynamic DNA methylation programs persistent adverse effects of early-life stressQ28264120
Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosineQ28281009
Effects of arsenic exposure on DNA methylation and epigenetic gene regulationQ28395938
Transgenerational epigenetic programming of the brain transcriptome and anxiety behaviorQ28474029
Covalent modification of DNA regulates memory formationQ28576256
Childhood adversity and epigenetic modulation of the leukocyte glucocorticoid receptor: preliminary findings in healthy adultsQ28732427
Effects of stress throughout the lifespan on the brain, behaviour and cognitionQ29615801
Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responsesQ29619379
Brain-derived neurotrophic factor epigenetic modifications associated with schizophrenia-like phenotype induced by prenatal stress in miceQ30416726
Parental olfactory experience influences behavior and neural structure in subsequent generationsQ30435813
Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice.Q30439246
Hippocampal dysfunction and cognitive impairments provoked by chronic early-life stress involve excessive activation of CRH receptorsQ30476161
Epigenetic and immune function profiles associated with posttraumatic stress disorderQ30478641
Sex-specific programming of offspring emotionality after stress early in pregnancyQ30489745
Acute episodes of predator exposure in conjunction with chronic social instability as an animal model of post-traumatic stress disorderQ30493506
Overweight and CpG methylation of the Pomc promoter in offspring of high-fat-diet-fed dams are not "reprogrammed" by regular chow diet in rats.Q33576250
Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulationQ33584767
Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptationQ33627434
TET enzymes, TDG and the dynamics of DNA demethylation.Q33715010
Prenatal stress decreases Bdnf expression and increases methylation of Bdnf exon IV in ratsQ33740700
Non-CG methylation patterns shape the epigenetic landscape in Arabidopsis.Q33921275
Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspringQ34022919
The 'Trier Social Stress Test'--a tool for investigating psychobiological stress responses in a laboratory settingQ34060992
Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactionsQ34062101
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbensQ34086476
Maternal methyl supplements in mice affect epigenetic variation and DNA methylation of offspringQ34143026
Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related GenesQ34157520
Transgenerational inheritance of stress pathologyQ34161652
DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm.Q34215833
Conserved epigenetic sensitivity to early life experience in the rat and human hippocampusQ36336199
The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenicQ36339038
Sex-specific epigenetic disruption and behavioral changes following low-dose in utero bisphenol A exposure.Q36932389
PTSD and DNA Methylation in Select Immune Function Gene Promoter Regions: A Repeated Measures Case-Control Study of U.S. Military Service MembersQ36948942
Epigenetic perspective on the developmental effects of bisphenol A.Q36988290
Genome-wide epigenetic regulation by early-life trauma.Q37191419
Mouse models of MeCP2 disorders share gene expression changes in the cerebellum and hypothalamusQ37223275
The case for transgenerational epigenetic inheritance in humansQ37229245
DNA methylation in repetitive elements and post-traumatic stress disorder: a case-control study of US military service membersQ37259389
Transgenerational epigenetic effects.Q37259670
Does intergenerational transmission of trauma skip a generation? No meta-analytic evidence for tertiary traumatization with third generation of Holocaust survivorsQ37261436
DNA excision repair proteins and Gadd45 as molecular players for active DNA demethylationQ37335285
Differential methylation of genes in the medial prefrontal cortex of developing and adult rats following exposure to maltreatment or nurturing care during infancyQ37358189
Exposure to caregiver maltreatment alters expression levels of epigenetic regulators in the medial prefrontal cortexQ37378167
Neonatal maternal separation alters the capacity of adult neural precursor cells to differentiate into neurons via methylation of retinoic acid receptor gene promoterQ37590351
Hungry in the womb: what are the consequences? Lessons from the Dutch famineQ37908430
DNA methylation and its basic functionQ38025275
Nongenetic inheritance and transgenerational epigeneticsQ38324465
Transgenerational sex-specific impact of preconception stress on the development of dendritic spines and dendritic length in the medial prefrontal cortexQ39098273
Methyl CpG binding domain ultra-sequencing: a novel method for identifying inter-individual and cell-type-specific variation in DNA methylationQ39266253
Differential susceptibility to chronic social defeat stress relates to the number of Dnmt3a-immunoreactive neurons in the hippocampal dentate gyrus.Q39271281
Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice.Q39284773
Epigenetic status of Gdnf in the ventral striatum determines susceptibility and adaptation to daily stressful events.Q39603610
Transgenerational effects of infantile adversity and enrichment in male and female ratsQ39721216
Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptorQ34290281
Epigenetic effects of prenatal stress on 11β-hydroxysteroid dehydrogenase-2 in the placenta and fetal brainQ34326531
Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorderQ34341949
DNA methylation profiles within the serotonin transporter gene moderate the association of 5-HTTLPR and cortisol stress reactivityQ34370519
Epigenomic profiling of men exposed to early-life stress reveals DNA methylation differences in association with current mental stateQ34370543
Bdnf DNA methylation modifications in the hippocampus and amygdala of male and female rats exposed to different caregiving environments outside the homecageQ34381502
Methylation at 5HTT mediates the impact of child sex abuse on women's antisocial behavior: an examination of the Iowa adoptee sampleQ34468779
Maternal care associated with methylation of the estrogen receptor-alpha1b promoter and estrogen receptor-alpha expression in the medial preoptic area of female offspring.Q34499207
DNA methylation signatures link prenatal famine exposure to growth and metabolismQ34581536
Maternal stress induces epigenetic signatures of psychiatric and neurological diseases in the offspringQ34602813
Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sitesQ34993956
Epigenetic reprogramming in early mammalian development and following somatic nuclear transfer.Q35043720
Early-life stress reduces DNA methylation of the Pomc gene in male mice.Q35088813
SLC6A4 methylation modifies the effect of the number of traumatic events on risk for posttraumatic stress disorderQ35134486
Epigenetic upregulation of corticotrophin-releasing hormone mediates postnatal maternal separation-induced memory deficiencyQ35144289
Transgenerational epigenetic inheritance in plantsQ35178183
Early life programming and neurodevelopmental disordersQ35201642
Oxytocin receptor gene methylation: converging multilevel evidence for a role in social anxietyQ35421263
Paternal transmission of stress-induced pathologies.Q35552812
Epigenetic vestiges of early developmental adversity: childhood stress exposure and DNA methylation in adolescenceQ35605903
Prenatal stress and risk for psychopathology: specific effects or induction of general susceptibility?Q35626351
Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice.Q35760210
Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder.Q35799705
Increased methylation of glucocorticoid receptor gene (NR3C1) in adults with a history of childhood maltreatment: a link with the severity and type of traumaQ35844162
Epigenetic regulation of BDNF gene transcription in the consolidation of fear memoryQ35851895
Epigenetic changes in fetal hypothalamic energy regulating pathways are associated with maternal undernutrition and twinningQ35863756
Global profiling of DNA methylation erasure in mouse primordial germ cellsQ35864711
Epigenetic modification of hippocampal Bdnf DNA in adult rats in an animal model of post-traumatic stress disorder.Q35910727
Effects of genotype and child abuse on DNA methylation and gene expression at the serotonin transporterQ36029492
Maternal deprivation in rats is associated with corticotrophin-releasing hormone (CRH) promoter hypomethylation and enhances CRH transcriptional responses to stress in adulthood.Q36049369
Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generationsQ36150116
DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brainQ36176889
Dynamic changes in DNA methylation of stress-associated genes (OXTR, BDNF ) after acute psychosocial stress.Q36203425
Differential patterns of whole-genome DNA methylation in institutionalized children and children raised by their biological parents.Q36315846
P921main subjectDNA methylationQ874745
P304page(s)76-84
P577publication date2015-04-23
P1433published inSeminars in Cell & Developmental BiologyQ14330411
P1476titleEvidence from clinical and animal model studies of the long-term and transgenerational impact of stress on DNA methylation
P478volume43

Reverse relations

cites work (P2860)
Q37237475Brain Reward Pathway Dysfunction in Maternal Depression and Addiction: A Present and Future Transgenerational Risk
Q38840948Caregiver maltreatment causes altered neuronal DNA methylation in female rodents
Q37589632Changes in Communication between Muscle Stem Cells and their Environment with Aging.
Q30359595Consequences of early adverse rearing experience(EARE) on development: insights from non-human primate studies.
Q36892975DNA methylation in Huntington's disease: Implications for transgenerational effects
Q38763849Does maternal mental well-being in pregnancy impact the early human epigenome?
Q89475594Epigenetic effects of environmental chemicals: insights from zebrafish
Q55284198Epigenetic machine learning: utilizing DNA methylation patterns to predict spastic cerebral palsy.
Q48529561Impact of exercise and a complex environment on hippocampal dendritic morphology, Bdnf gene expression, and DNA methylation in male rat pups neonatally exposed to alcohol
Q38968515Insight from animal models of environmentally driven epigenetic changes in the developing and adult brain
Q50535105Polyphenolic Compounds Alter Stress-Induced Patterns of Global DNA Methylation in Brain and Blood.
Q64949779Stress Across Generations: DNA Methylation as a Potential Mechanism Underlying Intergenerational Effects of Stress in Both Post-traumatic Stress Disorder and Pre-clinical Predator Stress Rodent Models.
Q36228126Tertiary Epimutations - A Novel Aspect of Epigenetic Transgenerational Inheritance Promoting Genome Instability
Q36915547The effects of maternal anxiety during pregnancy on IGF2/H19 methylation in cord blood
Q38832374The transgenerational transmission of childhood adversity: behavioral, cellular, and epigenetic correlates
Q47582907Thinking Across Generations: Unique Contributions of Maternal Early Life and Prenatal Stress to Infant Physiology
Q47582166Transgenerational blunting of morphine-induced corticosterone secretion is associated with dysregulated gene expression in male offspring

Search more.