Structural evidence that botulinum toxin blocks neuromuscular transmission by impairing the calcium influx that normally accompanies nerve depolarization

scientific article published on January 1, 1981

Structural evidence that botulinum toxin blocks neuromuscular transmission by impairing the calcium influx that normally accompanies nerve depolarization is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1083/JCB.88.1.160
P953full work available at URLhttps://europepmc.org/articles/PMC2111719
https://europepmc.org/articles/PMC2111719?pdf=render
https://rupress.org/jcb/article-pdf/88/1/160/1638073/160.pdf
P932PMC publication ID2111719
P698PubMed publication ID6259176
P5875ResearchGate publication ID16937452

P2093author name stringN. Hirokawa
J. E. Heuser
P2860cites workFailure of neuromuscular propagation in ratsQ24540445
The action of botulinum toxin on the neuro-muscular junctionQ24544021
Synaptic vesicle exocytosis captured by quick freezing and correlated with quantal transmitter releaseQ24682015
Mitochondria and calcium ion transportQ34053092
Correlation of transmitter release with membrane properties of the presynaptic fiber of the squid giant synapseQ34205920
Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junctionQ34207383
ELECTRON MICROSCOPIC OBSERVATIONS ON THE ACCUMULATION OF DIVALENT CATIONS IN INTRAMITOCHONDRIAL GRANULESQ36185879
Changes in the fine structure of the neuromuscular junction of the frog caused by black widow spider venomQ36193927
Calcium binding to intestinal membranesQ36194225
Binding of Clostridium botulinum neurotoxin to the presynaptic membrane in the central nervous systemQ36203799
Freeze-fracture studies of frog neuromuscular junctions during intense release of neurotransmitter. I. Effects of black widow spider venom and Ca2+-free solutions on the structure of the active zoneQ36203807
Visualization of stimulated nerve endings by preferential calcium accumulation of mitochondriaQ36698758
On the role of mitochondria in transmitter release from motor nerve terminalsQ39338197
Effects of botulinum toxin on neuromuscular transmission in the ratQ40015997
Action of brown widow spider venom and botulinum toxin on the frog neuromuscular junction examined with the freeze-fracture techniqueQ40124482
Pharmacological studies on the subcellular site of action of botulinum toxin type AQ40179354
EFFECT OF ACTIVE ACCUMULATION OF CALCIUM AND PHOSPHATE IONS ON THE STRUCTURE OF RAT LIVER MITOCHONDRIAQ41061336
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Synaptic transmission in squid giant synapse after potassium conductance blockage with external 3- and 4-aminopyridineQ41484337
An ultrastructural investigation of calcium-dependent granules in the rat neuropilQ42437994
The occurrence of intramitochondrial granules in nerve cellsQ43568722
Black widow spider venom: effect of purified toxin on lipid bilayer membranesQ43940764
Localization of calcium deposits in the frog neuromuscular junction at rest and following stimulationQ48402417
The timing of calcium action during neuromuscular transmission.Q52756725
Observations on the action of type A botulinum toxin on frog neuromuscular junctions.Q54579977
Localization of radioactive125I-Labelled botulinus toxin at the neuromuscular junction of mouse diaphragmQ66914297
An ultrastructural study of nerve and glial cells by freeze-substitutionQ67246713
Suppression by elevated calcium of black widow spider venom activity at frog neuromuscular junctionsQ67716515
The effect of type D botulinum toxin on frog neuromuscular junctionsQ68630516
Strontium and quantal release of transmitter at the neuromuscular junctionQ68731599
Structural and functional changes of frog neuromuscular junctions in high calcium solutionsQ68757142
Functional changes in frog neuromuscular junctions studied with freeze-fractureQ69342570
An intracellular study of the action of repetitive nerve volleys and of botulinum toxin on miniature end-plate potentialsQ74393536
The effect of calcium ions on the motor end-plate potentialsQ76227269
THE EFFECT OF CALCIUM ON ACETYLCHOLINE RELEASE FROM MOTOR NERVE TERMINALSQ78303263
The Most Poisonous PoisonQ78813035
Supersensitivity of skeletal muscle produced by botulinum toxinQ79287236
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)160-171
P577publication date1981-01-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleStructural evidence that botulinum toxin blocks neuromuscular transmission by impairing the calcium influx that normally accompanies nerve depolarization
P478volume88