Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

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Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis is …
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scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.1221789
P932PMC publication ID3432565
P698PubMed publication ID22674328
P5875ResearchGate publication ID225275591

P50authorMarla DubinskyQ30501395
Dermot McGovernQ59702746
Jerome I RotterQ59813011
Kent D TaylorQ89467237
P2093author name stringJordan Brown
Gordon D Brown
Iliyan D Iliev
Vincent A Funari
Samuel P Strom
Hanlin L Wang
Christopher N Reyes
Courtney A Becker
Phillip R Fleshner
David M Underhill
Quoclinh Nguyen
P2860cites workNovel Anti-Glycan Antibodies Related to Inflammatory Bowel Disease Diagnosis and PhenotypeQ22251117
Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasomeQ24303046
Enterotypes of the human gut microbiomeQ24489818
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A human gut microbial gene catalogue established by metagenomic sequencingQ24618931
Human dectin-1 deficiency and mucocutaneous fungal infectionsQ24645008
A homozygous CARD9 mutation in a family with susceptibility to fungal infectionsQ24658090
Multiple sequence alignment with the Clustal series of programsQ24672842
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A New Statistical Method for Haplotype Reconstruction from Population DataQ27860495
The Sequence Alignment/Map format and SAMtoolsQ27860966
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Genetic predictors of medically refractory ulcerative colitisQ28943368
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A comparison of bayesian methods for haplotype reconstruction from population genotype dataQ29547566
The Cardiovascular Health Study: design and rationaleQ29614874
Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5Q29615053
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitisQ29616155
Host-mediated inflammation disrupts the intestinal microbiota and promotes the overgrowth of EnterobacteriaceaeQ33306722
Fungi and inflammatory bowel diseases: Alterations of composition and diversityQ33347197
Characterization of the oral fungal microbiome (mycobiome) in healthy individualsQ33523794
Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments.Q33937171
Enterobacteriaceae act in concert with the gut microbiota to induce spontaneous and maternally transmitted colitisQ34187114
Abundant and diverse fungal microbiota in the murine intestineQ34315970
Dectin-1 is required for beta-glucan recognition and control of fungal infectionQ35837153
Accurate taxonomy assignments from 16S rRNA sequences produced by highly parallel pyrosequencersQ36935436
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasisQ37106755
Recent progress in understanding the phenotype and function of intestinal dendritic cells and macrophagesQ37349757
The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicansQ42385375
Gut CD103+ dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction.Q43081763
A software pipeline for processing and identification of fungal ITS sequencesQ43171943
A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypesQ43883077
Intestinal epithelial cells promote colitis-protective regulatory T-cell differentiation through dendritic cell conditioning.Q46040098
Selected loss of tolerance evidenced by Crohn's disease-associated immune responses to auto- and microbial antigensQ46134666
Colonization of Mice byCandida albicansIs Promoted by Chemically Induced Colitis and Augments Inflammatory Responses through Galectin‐3Q56019292
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17Q56880713
P433issue6086
P407language of work or nameEnglishQ1860
P921main subjectcolitisQ2453464
P304page(s)1314-1317
P577publication date2012-06-06
P1433published inScienceQ192864
P1476titleInteractions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis
P478volume336

Reverse relations

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Q34505062Small RNAs from plants, bacteria and fungi within the order Hypocreales are ubiquitous in human plasma
Q28259100Small intestinal fungal overgrowth
Q37380773Sodium methyldithiocarbamate exerts broad inhibition of cellular signaling and expression of effector molecules of inflammation
Q37092848Striking a balance: fungal commensalism versus pathogenesis
Q58122572Structure Dependent-Immunomodulation by Sugar Beet Arabinans via a SYK Tyrosine Kinase-Dependent Signaling Pathway
Q35044638Structure and function of the human skin microbiome
Q90283978Studying fungal pathogens of humans and fungal infections: fungal diversity and diversity of approaches
Q38184870Symbiosis as a general principle in eukaryotic evolution
Q26797310Systems Level Dissection of Candida Recognition by Dectins: A Matter of Fungal Morphology and Site of Infection
Q57146421TLR4, TLR9, and NLRP3 in biliary epithelial cells of primary sclerosing cholangitis: relationship with clinical characteristics
Q37157676Tailored immunity at mucosae
Q37015604The C-Type Lectin Receptor SIGNR3 Binds to Fungi Present in Commensal Microbiota and Influences Immune Regulation in Experimental Colitis
Q39260239The Cell Biology of the Trichosporon-Host Interaction
Q90223876The Dysbiosis and Inter-Kingdom Synergy Model in Oropharyngeal Candidiasis, a New Perspective in Pathogenesis
Q35880704The Effect of Lactobacillus casei 32G on the Mouse Cecum Microbiota and Innate Immune Response Is Dose and Time Dependent
Q38639804The Fungal Frontier: A Comparative Analysis of Methods Used in the Study of the Human Gut Mycobiome.
Q36271354The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host.
Q36346259The Gut Microbiome: Connecting Spatial Organization to Function
Q57492072The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease
Q37521076The HOG pathway is critical for the colonization of the mouse gastrointestinal tract by Candida albicans
Q47711287The Human Mucosal Mycobiome and Fungal Community Interactions
Q36034914The Impact of Lactobacillus casei on the Composition of the Cecal Microbiota and Innate Immune System Is Strain Specific
Q55385103The Intestinal Mycobiota in Wild Zebrafish Comprises Mainly Dothideomycetes While Saccharomycetes Predominate in Their Laboratory-Reared Counterparts.
Q28067461The Multibiome: The Intestinal Ecosystem's Influence on Immune Homeostasis, Health, and Disease
Q52664476The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis.
Q93186295The Potential Role of Gut Mycobiome in Irritable Bowel Syndrome
Q91303785The Relationship of Candida albicans with the Oral Bacterial Microbiome in Health and Disease
Q26752567The Role of Autophagy-Related Proteins in Candida albicans Infections
Q39308885The Role of Carrageenan and Carboxymethylcellulose in the Development of Intestinal Inflammation
Q36786137The Role of Dectin-2 for Host Defense Against Disseminated Candidiasis
Q38328470The adaptor CARD9 is required for adaptive but not innate immunity to oral mucosal Candida albicans infections
Q38441242The effect of host genetics on the gut microbiome
Q34727901The emerging world of the fungal microbiome
Q90355998The evidence for fungus in Crohn's disease pathogenesis
Q26853435The ground state of innate immune responsiveness is determined at the interface of genetic, epigenetic, and environmental influences
Q38884056The gut microbiota and inflammatory bowel diseases
Q46253527The gut mycobiome of the Human Microbiome Project healthy cohort.
Q92063098The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases
Q36153323The human gastrointestinal tract and oral microbiota in inflammatory bowel disease: a state of the science review.
Q35408304The human mycobiome
Q28295636The human mycobiome in health and disease
Q38293766The innate immune system and inflammatory bowel disease.
Q26745700The intestinal microbiome, barrier function, and immune system in inflammatory bowel disease: a tripartite pathophysiological circuit with implications for new therapeutic directions
Q35082308The lung mycobiome: an emerging field of the human respiratory microbiome.
Q91749460The mammalian mycobiome: A complex system in a dynamic relationship with the host
Q34311522The microbial basis of inflammatory bowel diseases
Q35215942The microbial eukaryote Blastocystis is a prevalent and diverse member of the healthy human gut microbiota.
Q36069070The microbiome and innate immunity
Q38182899The microbiome and psoriatic arthritis
Q38949256The microbiome in asthma
Q39001907The microbiome-metabolome crosstalk in the pathogenesis of respiratory fungal diseases
Q33806817The microbiota in inflammatory bowel disease: current and therapeutic insights
Q37634456The mycobiome of the human urinary tract: potential roles for fungi in urology
Q90159677The mycobiota of the human body: a spark can start a prairie fire
Q35096262The mycobiota: interactions between commensal fungi and the host immune system.
Q35277785The potential impact of the pulmonary microbiome on immunopathogenesis of Aspergillus-related lung disease
Q36906422The regulatory power of glycans and their binding partners in immunity
Q34700824The response of human macrophages to β-glucans depends on the inflammatory milieu.
Q36147431The role of pattern recognition receptors in the innate recognition of Candida albicans
Q47563895The triune of intestinal microbiome, genetics and inflammatory status and its impact on the healing of lower gastrointestinal anastomoses
Q28660380The virome in mammalian physiology and disease
Q47138923The yeast form of the fungus Candida albicans promotes persistence in the gut of gnotobiotic mice
Q58713172There was collusion: Microbes in inflammatory bowel disease
Q47565602Through the Scope Darkly: The Gut Mycobiome Comes into Focus
Q89560976Time of Feeding Alters Obesity-Associated Parameters and Gut Bacterial Communities, but Not Fungal Populations, in C57BL/6 Male Mice
Q97905226Tissue-resident memory Th17 cells maintain stable fungal commensalism in the oral mucosa
Q34734628Topographic diversity of fungal and bacterial communities in human skin
Q38171924Towards personalized care in IBD.
Q45760347Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22.
Q43499673Tuning of skin immunity by skin commensal bacteria
Q92071463Unaltered Fungal Burden and Lethality in Human CEACAM1-Transgenic Mice During Candida albicans Dissemination and Systemic Infection
Q27002380Upper gastrointestinal microbiota and digestive diseases
Q52579441Urbanization and the gut microbiota in health and inflammatory bowel disease.
Q34384544Use of animal models in elucidating disease pathogenesis in IBD.
Q35040842Using Bayesian modelling to investigate factors governing antibiotic-induced Candida albicans colonization of the GI tract
Q35905803Viral immunity. Transkingdom control of viral infection and immunity in the mammalian intestine
Q34585227Waiting for the human intestinal Eukaryotome
Q34376721Yeast communities of diverse Drosophila species: comparison of two symbiont groups in the same hosts
Q33590266Yeast modulation of human dendritic cell cytokine secretion: an in vitro study
Q92859509mSphere of Influence: the Mycobiota in Human Health and Disease
Q47606694β-Glucans in food modify colonic microflora by inducing antimicrobial protein, calprotectin, in a Dectin-1-induced-IL-17F-dependent manner.
Q37525770β-glucan Exposure on the Fungal Cell Wall Tightly Correlates with Competitive Fitness of Candida Species in the Mouse Gastrointestinal Tract

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