Design of the Study of Tranexamic Acid during Air Medical Prehospital Transport (STAAMP) Trial: Addressing the Knowledge Gaps

scientific article

Design of the Study of Tranexamic Acid during Air Medical Prehospital Transport (STAAMP) Trial: Addressing the Knowledge Gaps is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/10903127.2014.936635
P932PMC publication ID4623322
P698PubMed publication ID25076119

P50authorFrancis X. GuyetteQ52091909
Jason L SperryQ114416071
Timothy BilliarQ30223707
Joshua B. BrownQ44423621
P2093author name stringAndrew B Peitzman
Brian S Zuckerbraun
Matthew D Neal
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Early coagulopathy predicts mortality in traumaQ47766285
Association of cryoprecipitate and tranexamic acid with improved survival following wartime injury: findings from the MATTERs II Study.Q50491141
Hyperfibrinolysis at admission is an uncommon but highly lethal event associated with shock and prehospital fluid administrationQ64039987
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Effects of C1 inhibitor on tissue damage in a porcine model of controlled hemorrhageQ84344626
Prehospital use of tranexamic acid for hemorrhagic shock in primary and secondary air medical evacuationQ85196373
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Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trialQ28285511
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Tranexamic acid, fibrinogen concentrate, and prothrombin complex concentrate: data to support prehospital use?Q30705540
Criteria for empiric treatment of hyperfibrinolysis after traumaQ33402032
Antifibrinolytic therapy: new data and new conceptsQ33606553
Fibrinolysis greater than 3% is the critical value for initiation of antifibrinolytic therapy.Q33810788
Tranexamic acid in trauma: how should we use it?Q34345917
Validation of postinjury multiple organ failure scoresQ35072968
Disruption of the mucosal barrier during gut ischemia allows entry of digestive enzymes into the intestinal wallQ35783195
Tranexamic acid attenuates inflammatory response in cardiopulmonary bypass surgery through blockade of fibrinolysis: a case control study followed by a randomized double-blind controlled trialQ36465380
Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerationsQ36501096
Characterization of acute coagulopathy and sexual dimorphism after injury: females and coagulopathy just do not mix.Q36520866
Fibrinolysis, inflammation, and regulation of the plasminogen activating systemQ36884356
Early resuscitation intensity as a surrogate for bleeding severity and early mortality in the PROMMTT studyQ37097012
The coagulopathy of trauma: a review of mechanismsQ37292306
Acute traumatic coagulopathy: from endogenous acute coagulopathy to systemic acquired coagulopathy and backQ37917494
Plasmin as a proinflammatory cell activator.Q38007805
The acute coagulopathy of trauma: mechanisms and tools for risk stratificationQ38050045
Tranexamic acid and trauma: current status and knowledge gaps with recommended research prioritiesQ38065891
An update on the coagulopathy of traumaQ38160131
The importance of early treatment with tranexamic acid in bleeding trauma patients: An exploratory analysis of the CRASH-2 randomised controlled trialQ39401875
Early complementopathy after multiple injuries in humansQ42578085
Increased mortality associated with the early coagulopathy of trauma in combat casualtiesQ44113097
Tranexamic acid in the prehospital setting: Israel Defense Forces' initial experienceQ44195932
Primary fibrinolysis is integral in the pathogenesis of the acute coagulopathy of traumaQ44405049
The incidence and magnitude of fibrinolytic activation in trauma patientsQ44658013
Stability of tranexamic acid after 12-week storage at temperatures from -20°c to 50°cQ44839573
Military Application of Tranexamic Acid in Trauma Emergency Resuscitation (MATTERs) Study.Q45103688
Effect of consent rituals on mortality in emergency care researchQ45117645
The epidemiology of traumatic death. A population-based analysisQ46056719
Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?Q46166562
Role of the alternative pathway in the early complement activation following major traumaQ46258966
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttranexamic acidQ418666
knowledge gap hypothesisQ1481327
knowledge gapQ122958306
P304page(s)79-86
P577publication date2014-07-30
P1433published inPrehospital Emergency CareQ7239978
P1476titleDesign of the Study of Tranexamic Acid during Air Medical Prehospital Transport (STAAMP) Trial: Addressing the Knowledge Gaps
P478volume19

Reverse relations

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Q26785966CRASH-2 Study of Tranexamic Acid to Treat Bleeding in Trauma Patients: A Controversy Fueled by Science and Social Media
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