The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling

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The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M112.362681
P932PMC publication ID3436188
P698PubMed publication ID22773843
P5875ResearchGate publication ID228447348

P50authorSteven A StackerQ47504025
Graham J LieschkeQ55149847
Maria L. MachedaQ58482976
Neil I BowerQ59560912
Alain DabdoubQ39464890
Benjamin M HoganQ39860533
P2093author name stringYou Fang Zhang
Michael M Halford
Bonnie E Jacques
Kumudhini Kugathasan
Willy W Sun
P2860cites workMammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowthQ24305583
Molecular cloning and chromosomal localisation of the human homologue of a receptor related to tyrosine kinases (RYK)Q24314925
RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifsQ24563042
Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulationQ24672832
Revelations of the RYK receptorQ28141399
Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimersQ28146110
Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouseQ28184694
Wnt5a functions in planar cell polarity regulation in miceQ28505898
Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.Q50483907
Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesisQ28506743
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathwayQ28509023
Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tractQ28509875
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube developmentQ28511382
The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosumQ28511771
Wnt5a regulates midbrain dopaminergic axon growth and guidanceQ28568522
Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closureQ28588549
Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalkQ28589209
Identification of Vangl2 and Scrb1 as planar polarity genes in mammalsQ28593071
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cellsQ28593180
Dishevelled controls cell polarity during Xenopus gastrulationQ29619295
Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulationQ29619296
Shaping the vertebrate body plan by polarized embryonic cell movementsQ30310311
Wnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanismsQ30488242
Vang-like protein 2 and Rac1 interact to regulate adherens junctionsQ33629181
Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway.Q33898502
Wnt5b-Ryk pathway provides directional signals to regulate gastrulation movement.Q34092446
Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signalingQ34211643
The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development.Q34460263
Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2Q34706774
Roles of planar cell polarity pathways in the development of neural [correction of neutral] tube defectsQ35218565
Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motilityQ36710748
Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochleaQ36984946
Importance of Wnt signaling in the tumor stroma microenvironment.Q37264578
Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutationsQ38298376
Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movementsQ38360630
Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidanceQ39726927
Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movementsQ40110545
VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish.Q41833680
Wnt-3a-dependent cell motility involves RhoA activation and is specifically regulated by dishevelled-2.Q45127810
Receptor related to tyrosine kinase RYK regulates cell migration during cortical developmentQ46409568
Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mappingQ46799004
The function of silberblick in the positioning of the eye anlage in the zebrafish embryoQ47073722
P433issue35
P407language of work or nameEnglishQ1860
P304page(s)29312-29323
P577publication date2012-07-06
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling
P478volume287