Full-length prepro-alpha-factor can be translocated across the mammalian microsomal membrane only if translation has not terminated

scientific article

Full-length prepro-alpha-factor can be translocated across the mammalian microsomal membrane only if translation has not terminated is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.106.4.1043
P932PMC publication ID2115022
P698PubMed publication ID2834400
P5875ResearchGate publication ID20322646

P2093author name stringP Walter
P D Garcia
P2860cites workThe signal recognition particle receptor is a complex that contains two distinct polypeptide chainsQ24680311
Protein translocation across the endoplasmic reticulum. I. Detection in the microsomal membrane of a receptor for the signal recognition particleQ24680984
Translocation of proteins across the endoplasmic reticulum. I. Signal recognition protein (SRP) binds to in-vitro-assembled polysomes synthesizing secretory proteinQ24681488
Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulumQ28275854
Intracellular Aspects of the Process of Protein SynthesisQ29615237
Transfer of proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous componentsQ36204254
Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranesQ36205578
Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptorQ36209511
Elongation arrest is not a prerequisite for secretory protein translocation across the microsomal membraneQ36212258
Secretory protein translocation in a yeast cell-free system can occur posttranslationally and requires ATP hydrolysisQ36215035
Formation of a functional ribosome-membrane junction during translocation requires the participation of a GTP-binding proteinQ36216572
Posttranslational translocation of influenza virus hemagglutinin across microsomal membranesQ36923205
Photocrosslinking of the signal sequence of nascent preprolactin to the 54-kilodalton polypeptide of the signal recognition particleQ37407450
M13 procoat and a pre-immunoglobulin share processing specificity but use different membrane receptor mechanismsQ37611240
Translocation of secretory proteins across the microsomal membrane occurs through an environment accessible to aqueous perturbantsQ38352117
Import of frog prepropeptide GLa into microsomes requires ATP but does not involve docking protein or ribosomesQ41335865
The mode of action of alpha sarcin and a novel assay of the puromycin reactionQ41833114
The human glucose transporter can insert posttranslationally into microsomesQ41838195
Secretion in yeast: translocation and glycosylation of prepro-alpha-factor in vitro can occur via an ATP-dependent post-translational mechanism.Q42149047
Post-translational insertion of a fragment of the glucose transporter into microsomes requires phosphoanhydride bond cleavageQ45133249
A signal sequence receptor in the endoplasmic reticulum membraneQ46128766
53 Signal recognition particle: A ribonucleoprotein required for cotranslational translocation of proteins, isolation and propertiesQ48850685
Preparation of microsomal membranes for cotranslational protein translocationQ49487241
Cell-free translation of messenger RNA in a wheat germ systemQ49487259
Demonstration of post-translational secretion of human placental lactogen by a mammalian in vitro translation system.Q54423924
Signal recognition. Two receptors act sequentially.Q54762597
Secretory protein translocation across membranes—the role of the ‘docking protein’Q59049591
The signal sequence of nascent preprolactin interacts with the 54K polypeptide of the signal recognition particleQ59071641
Import of honeybee prepromelittin into the endoplasmic reticulum. Requirements for membrane insertion, processing, and sequestrationQ69592944
Uncoupling translocation from translation: implications for transport of proteins across membranesQ70037497
In vitro protein translocation across the yeast endoplasmic reticulum: ATP-dependent posttranslational translocation of the prepro-alpha-factorQ70137148
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)1043-1048
P577publication date1988-04-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleFull-length prepro-alpha-factor can be translocated across the mammalian microsomal membrane only if translation has not terminated
P478volume106

Reverse relations

cites work (P2860)
Q35751874A calmodulin-dependent translocation pathway for small secretory proteins
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Q73107093An internal signal sequence mediates the targeting and retention of the human UDP-glucuronosyltransferase 1A6 to the endoplasmic reticulum
Q44757239Coordinated regulation of genes for secretion in tobacco at late developmental stages: association with resistance against oomycetes
Q70473381DIDS (4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid) inhibits an early step of protein translocation across the mammalian ER membrane
Q38311649Determinant of the extracellular location of the N-terminus of human multidrug-resistance-associated protein
Q41096292In vivo and in vitro analysis of ptl1, a yeast ts mutant with a membrane-associated defect in protein translocation
Q42125122Inhibition of 2A-mediated 'cleavage' of certain artificial polyproteins bearing N-terminal signal sequences.
Q37055727Insertion of proteins into bacterial membranes: mechanism, characteristics, and comparisons with the eucaryotic process
Q34567578Intracellular traffic of newly synthesized proteins. Current understanding and future prospects
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Q28243966Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
Q33589514New insights into signal recognition and elongation arrest activities of the signal recognition particle
Q36218468Prepro-carboxypeptidase Y and a truncated form of pre-invertase, but not full-length pre-invertase, can be posttranslationally translocated across microsomal vesicle membranes from Saccharomyces cerevisiae
Q38349808Presynaptic aspects of cotransmission: relationship between vesicles and neurotransmitters
Q37797593Ribonucleoparticle-independent transport of proteins into mammalian microsomes
Q36222336Saccharomyces cerevisiae and Schizosaccharomyces pombe contain a homologue to the 54-kD subunit of the signal recognition particle that in S. cerevisiae is essential for growth
Q49486756SecB functions as a cytosolic signal recognition factor for protein export in E. coli
Q56228657Signal Recognition Particle (SRP), a Ubiquitous Initiator of Protein Translocation
Q41094249Signal recognition particle (SRP) stabilizes the translocation-competent conformation of pre-secretory proteins
Q34309758Signal recognition particle (SRP), a ubiquitous initiator of protein translocation
Q42990350Species-specificity in endoplasmic reticulum signal peptide utilization revealed by proteins from Trypanosoma brucei and Leishmania
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Q27933070The refolding activity of the yeast heat shock proteins Ssa1 and Ssa2 defines their role in protein translocation
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Q35018270The signal sequence influences post-translational ER translocation at distinct stages

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