Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis

scientific article

Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1002/DVDY.22464
P932PMC publication ID3437621
P698PubMed publication ID19681164
P5875ResearchGate publication ID47719164

P2093author name stringRachel K Miller
Pierre D McCrea
P2860cites workLDL-receptor-related proteins in Wnt signal transductionQ24290392
Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cellsQ24299786
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutationQ24317412
Regulation of planar cell polarity by Smurf ubiquitin ligasesQ24317525
Signal transduction by the Wnt family of ligandsQ24530639
The planar polarity gene strabismus regulates convergent extension movements in XenopusQ24536211
The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signalingQ24540545
Interaction between RGS7 and polycystinQ24653605
Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulationQ24672832
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signalingQ24673748
Hyperactive Wnt signaling changes the developmental potential of embryonic lung endodermQ24791466
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cellsQ27860717
Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouseQ28184694
Convergent extension: the molecular control of polarized cell movement during embryonic developmentQ28204202
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1Q28214701
Disruption of scribble (Scrb1) causes severe neural tube defects in the circletail mouseQ28218970
The role of RhoA in tissue polarity and Frizzled signallingQ28238365
Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryosQ28242317
Diego and Prickle regulate Frizzled planar cell polarity signalling by competing for Dishevelled bindingQ28254777
Mutations affecting morphogenesis during gastrulation and tail formation in the zebrafish, Danio rerioQ28302050
Evidence for a mitogenic effect of Wnt-1 in the developing mammalian central nervous systemQ72106566
Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulationQ73691283
Retinal axon misrouting at the optic chiasm in mice with neural tube closure defectsQ73912821
Expression patterns of Wnt genes in mouse gut developmentQ74107411
Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin geneQ74604719
Endothelial cell influence on dorsal root ganglion cell formationQ75225152
Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cellsQ75236410
Axial elongation in the mouse and its retardation in homozygous looptail miceQ76495195
Molecular regulation of pronephric developmentQ77803712
A mitogen gradient of dorsal midline Wnts organizes growth in the CNSQ77960718
Wnt5a is required for cardiac outflow tract septation in miceQ80362379
Chick pulmonary Wnt5a directs airway and vascular tubulogenesisQ80785633
Signals which build a tubuleQ81441570
Wnt signals mediate a fate decision between otic placode and epidermisQ82444199
Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in XenopusQ28307143
Wnt5a functions in planar cell polarity regulation in miceQ28505898
Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growthQ28505930
Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchymeQ28506294
Wnt/beta-catenin signaling regulates nephron induction during mouse kidney developmentQ28506499
Induction of ureter branching as a response to Wnt-2b signaling during early kidney organogenesisQ28506528
Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closureQ28507430
Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2Q28507487
Guidance of trunk neural crest migration requires neuropilin 2/semaphorin 3F signalingQ28507757
Wnt-6 is expressed in the ureter bud and induces kidney tubule development in vitroQ28507791
Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesisQ28508102
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4Q28508296
beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesisQ28508592
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathwayQ28509023
Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary glandQ28510734
Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital systemQ28511083
Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleenQ28511280
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube developmentQ28511382
Beta-catenin is essential for pancreatic acinar but not islet developmentQ28512693
Wnt5a is essential for intestinal elongation in miceQ28584757
Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root gangliaQ28584790
Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formationQ28585730
Ciliary proteins link basal body polarization to planar cell polarity regulationQ28585995
The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brainQ28586297
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulationQ28587130
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migrationQ28587140
The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signalingQ28587498
Vangl2 acts via RhoA signaling to regulate polarized cell movements during development of the proximal outflow tractQ28587502
A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidneyQ28587526
Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lungQ28587734
Canonical Wnt signaling functions in second heart field to promote right ventricular growthQ28588651
The Wnt signaling receptor Lrp5 is required for mammary ductal stem cell activity and Wnt1-induced tumorigenesisQ28589724
Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesisQ28590588
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cellsQ30491381
Pulsed contractions of an actin-myosin network drive apical constrictionQ30493161
Wnt/Frizzled signaling controls C. elegans gastrulation by activating actomyosin contractilityQ30497437
The role of the polycystins in kidney developmentQ33691019
Towards a molecular anatomy of the Xenopus pronephric kidney.Q33759889
Side-branching in the mammary gland: the progesterone-Wnt connection.Q33843842
Wnt signalling in mammalian development and cancerQ33870394
Requirement of a neural tube signal for the differentiation of neural crest cells into dorsal root gangliaQ43788176
Differentiation and maturation of zebrafish dorsal root and sympathetic ganglion neuronsQ43947348
Essential function of Wnt-4 for tubulogenesis in the Xenopus pronephric kidney.Q44079507
Selective binding of lectins to embryonic chicken vasculatureQ44409385
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous systemQ44472635
Xenopus Dishevelled signaling regulates both neural and mesodermal convergent extension: parallel forces elongating the body axis.Q45980748
Mesodermal Wnt2b signalling positively regulates liver specification.Q45995605
Regulation of convergent extension in Xenopus by Wnt5a and Frizzled-8 is independent of the canonical Wnt pathwayQ46041157
Sensory nerves determine the pattern of arterial differentiation and blood vessel branching in the skinQ46623662
Pancreas-specific deletion of beta-catenin reveals Wnt-dependent and Wnt-independent functions during development.Q46708971
Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton.Q47070036
The ankyrin repeat protein Diego mediates Frizzled-dependent planar polarizationQ47070692
Patterned gene expression directs bipolar planar polarity in DrosophilaQ47071305
Control of tracheal tubulogenesis by Wingless signaling.Q47072501
Dual roles of zygotic and maternal Scribble1 in neural migration and convergent extension movements in zebrafish embryosQ47073230
Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathwaysQ47073543
Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movementsQ47073597
A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidneyQ47074132
Wnt signal transduction: more than one wat to skin a (beta-)cat?Q47986655
The neural tube patterns vessels developmentally using the VEGF signaling pathway.Q48005094
Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female miceQ48041933
JNK and ROKalpha function in the noncanonical Wnt/RhoA signaling pathway to regulate Xenopus convergent extension movementsQ48148721
Blood vessels form a scaffold for neuroblast migration in the adult olfactory bulb.Q48151551
Role of beta-catenin in the developing cortical and hippocampal neuroepitheliumQ48155430
Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse developmentQ48841883
Long-term time-lapse fluorescence imaging of developing zebrafish.Q50647707
Progressive restriction of otic fate: the role of FGF and Wnt in resolving inner ear potential.Q50776563
Imaging neural crest cell dynamics during formation of dorsal root ganglia and sympathetic ganglia.Q50784026
Wnt7b regulates mesenchymal proliferation and vascular development in the lung.Q51701912
Wnt11r is required for cranial neural crest migration.Q51947640
GATA transcription factors integrate Wnt signalling during heart development.Q51950738
DM-GRASP/ALCAM/CD166 is required for cardiac morphogenesis and maintenance of cardiac identity in first heart field derived cells.Q51953129
Frizzled5/8 is required in secondary mesenchyme cells to initiate archenteron invagination during sea urchin development.Q52029441
Expression pattern of Wnt signaling components in the adult intestine.Q52042359
Dickkopf-1 (DKK1) reveals that fibronectin is a major target of Wnt signaling in branching morphogenesis of the mouse embryonic lung.Q52061734
Identification of the mammary line in mouse by Wnt10b expression.Q52094358
Wnt signaling during development of the gastrointestinal tract.Q52102720
Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye.Q52165280
WNT11 promotes cardiac tissue formation of early mesoderm.Q52174716
Wnt signalling required for expansion of neural crest and CNS progenitors.Q52192233
Wnt-4 expression induces a pregnancy-like growth pattern in reconstituted mammary glands in virgin mice.Q52206864
Hu neuronal proteins are expressed in proliferating neurogenic cells.Q52219021
Wingless and its signalling pathway have common and separable functions during tracheal development.Q52582885
From cilia to cyst.Q55036761
Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway.Q33898502
Wnt antagonism initiates cardiogenesis in Xenopus laevisQ33931613
Seven Wnt homologues in Drosophila: a case study of the developing tracheaeQ33951975
Shaping the mammalian auditory sensory organ by the planar cell polarity pathwayQ34154050
Neurovascular congruence results from a shared patterning mechanism that utilizes Semaphorin3A and Neuropilin-1.Q34181370
Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.Q34395279
Common mechanisms of nerve and blood vessel wiringQ34433723
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarityQ34455099
Regulation of early lung morphogenesis: questions, facts and controversiesQ34513653
It takes guts: the Drosophila hindgut as a model system for organogenesisQ34532395
Polycystic kidney disease: cell division without a c(l)ue?Q34544069
Gene function in mouse embryogenesis: get set for gastrulationQ34612511
Nodal flow and the generation of left-right asymmetry.Q34652060
Phases of canonical Wnt signaling during the development of mouse intestinal epitheliumQ34660140
Non-canonical Wnt signaling in Xenopus: regulation of axis formation and gastrulationQ34758581
Non-canonical Wnt signalling and regulation of gastrulation movementsQ34758596
Convergence and extension in vertebrate gastrulae: cell movements according to or in search of identity?Q34783796
The Xenopus pronephros as a model system for the study of kidney development and pathophysiology.Q34974054
Tube morphogenesis: making and shaping biological tubesQ35044542
Tube or not tube: remodeling epithelial tissues by branching morphogenesisQ35046568
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.Q35122385
Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesisQ35544524
Tube morphogenesis: closure, but many openings remainQ35587483
Planar cell polarity genes and neural tube closure.Q35639986
Wnt signaling regulates pancreatic beta cell proliferationQ35741102
Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cellsQ35808417
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitorsQ35865003
Making tubes in the Drosophila embryoQ36042641
Prickle and Strabismus form a functional complex to generate a correct axis during planar cell polarity signalingQ36065784
Epithelial morphogenesisQ36093263
Wnt signaling through canonical and non-canonical pathways: recent progressQ36194509
Morphogens in motion: growth control of the neural tubeQ36206016
Planar cell polarity and a potential role for a Wnt morphogen gradient in stereociliary bundle orientation in the mammalian inner ear.Q36206053
Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus developmentQ36236916
Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specificationQ28591062
A local Wnt-3a signal is required for development of the mammalian hippocampusQ28591198
Wnt-dependent regulation of inner ear morphogenesis is balanced by the opposing and supporting roles of Shh.Q28591489
Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammalsQ28591957
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4Q28592260
Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain regionQ28592616
Dynamic recruitment of axin by Dishevelled protein assembliesQ28592772
Identification of Vangl2 and Scrb1 as planar polarity genes in mammalsQ28593071
The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cellsQ28593180
Wnt5a participates in distal lung morphogenesisQ28593390
Essential function of Wnt-4 in mammary gland development downstream of progesterone signalingQ28594185
Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent mannerQ28613361
Ca(2+)/calmodulin-dependent protein kinase II is stimulated by Wnt and Frizzled homologs and promotes ventral cell fates in XenopusQ28613481
Role of frizzled 7 in the regulation of convergent extension movements during gastrulation in Xenopus laevisQ28613539
Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signalingQ28616347
Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathwaysQ28616373
Planar cell polarity signaling: from fly development to human diseaseQ28749129
Mechanisms of Wnt signaling in developmentQ29547537
The vertebrate primary cilium in development, homeostasis, and diseaseQ29614609
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathwaysQ29614619
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathwayQ29615176
Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genomeQ29616165
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activationQ29618700
A series of normal stages in the development of the chick embryo. 1951Q29618726
A second canon. Functions and mechanisms of beta-catenin-independent Wnt signalingQ29619294
Dishevelled controls cell polarity during Xenopus gastrulationQ29619295
Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulationQ29619296
Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumorsQ29619814
In vivo imaging of embryonic vascular development using transgenic zebrafishQ29619921
Mechanisms of convergence and extension by cell intercalationQ30306607
The planar cell polarity gene strabismus regulates convergence and extension and neural fold closure in XenopusQ30309547
The genetic control of tissue polarity in DrosophilaQ30311367
Model systems for the study of kidney development: use of the pronephros in the analysis of organ induction and patterningQ30428197
Cell migration during gastrulationQ30437765
Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of DrosophilaQ30442177
Planar cell polarity signalling couples cell division and morphogenesis during neurulation.Q30477078
Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signalingQ30479587
Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements.Q30481137
Planar cell polarization: an emerging model points in the right directionQ36280306
Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary glandQ36360340
Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.Q36381456
Vang-like 2 and noncanonical Wnt signaling in outflow tract development.Q36394655
The left-right axis in the mouse: from origin to morphologyQ36467624
The role of Wnt signalling in cardiac development and tissue remodelling in the mature heartQ36543886
Mechanisms of Disease: autosomal dominant and recessive polycystic kidney diseasesQ36577116
Planar cell polarity, ciliogenesis and neural tube defectsQ36599301
Planar cell polarity signaling: a common mechanism for cellular polarization.Q36606892
Gastrulation: Wnts signal constriction.Q36631009
The Scribble and Par complexes in polarity and migration: friends or foes?Q36635733
Wnts as ligands: processing, secretion and receptionQ36672661
Multiplicity of the interactions of Wnt proteins and their receptorsQ36692201
Tissue/planar cell polarity in vertebrates: new insights and new questionsQ36720615
Intestinal morphogenesisQ36724562
Molecular regulation of kidney development: is the answer blowing in the Wnt?Q36842478
Zebrafish gastrulation: cell movements, signals, and mechanismsQ36845712
Planar polarity and tissue morphogenesisQ36851258
Wnt/beta-catenin signaling and cardiogenesis: timing does matterQ36869551
Renal abnormalities and their developmental originQ36945522
The first steps towards hearing: mechanisms of otic placode induction.Q36950097
Gastrulation in C. elegansQ37020481
Wnt signaling in breast organogenesisQ37080183
Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewalQ37080793
Wnt/beta-catenin and noncanonical Wnt signaling interact in tissue evagination in the simple eumetazoan HydraQ37106903
Wnt/beta-catenin signaling: new (and old) players and new insightsQ37109729
Requirement of Wnt/beta-catenin signaling in pronephric kidney developmentQ37197987
Loss of TGF-beta or Wnt5a results in an increase in Wnt/beta-catenin activity and redirects mammary tumour phenotypeQ37208778
Endothelial cells promote migration and proliferation of enteric neural crest cells via beta1 integrin signalingQ37213009
Neurovascular congruence during cerebral cortical developmentQ37220151
Regulated adhesion as a driving force of gastrulation movementsQ37308883
Primary cilia in planar cell polarity regulation of the inner earQ37369343
Wnt signaling pathways meet Rho GTPases.Q37388913
Guidance of vascular development: lessons from the nervous system.Q37402196
Noncanonical Wnt/PCP signaling during vertebrate gastrulationQ37416717
Division of labor during trunk neural crest developmentQ37732864
The polycystic kidney disease-1 promoter is a target of the beta-catenin/T-cell factor pathwayQ38288606
beta-catenin/TCF/Lef controls a differentiation-associated transcriptional program in renal epithelial progenitorsQ38299235
Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafishQ38352359
Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.Q38520593
The planar cell-polarity gene stbm regulates cell behaviour and cell fate in vertebrate embryos.Q38523609
The prickle-related gene in vertebrates is essential for gastrulation cell movementsQ39750801
Wnt5a and Wnt11 interact in a maternal Dkk1-regulated fashion to activate both canonical and non-canonical signaling in Xenopus axis formationQ39752731
The function and mechanism of convergent extension during gastrulation of Xenopus laevisQ39805739
Canonical Wnt signals are essential for homeostasis of the intestinal epitheliumQ39895829
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.Q40036004
Canonical WNT signaling during kidney developmentQ40134356
Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domainsQ40264123
Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback.Q40465024
Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cellsQ40570664
Wnt signaling components in the chicken intestinal tractQ40598525
Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.Q40642802
Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesisQ40712030
Induced repatterning of type XVIII collagen expression in ureter bud from kidney to lung type: association with sonic hedgehog and ectopic surfactant protein C.Q40814557
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidneyQ41006079
Gut reaction to Wnt signaling in wormsQ41588808
Think globally, act locally: the making of a mouse mammary gland.Q41705141
Wnt11-R signaling regulates a calcium sensitive EMT event essential for dorsal fin development of XenopusQ42041530
JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebratesQ42113998
Notch signaling augments the canonical Wnt pathway to specify the size of the otic placodeQ42226422
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signalingQ42491186
Regional expression, pattern and timing of convergence and extension during gastrulation of Xenopus laevisQ42514448
The behaviour and function of bottle cells during gastrulation of Xenopus laevisQ42514455
Delamination of cells from neurogenic placodes does not involve an epithelial-to-mesenchymal transitionQ42520714
Wnt signaling in gut organogenesisQ42652916
Dishevelled proteins lead to two signaling pathways. Regulation of LEF-1 and c-Jun N-terminal kinase in mammalian cellsQ42823306
P433issue1
P304page(s)77-93
P577publication date2010-01-01
P1433published inDevelopmental DynamicsQ59752
P1476titleWnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis
P478volume239