Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells

scientific article

Signaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/STEM.1127
P8608Fatcat IDrelease_5k2sv7bex5c3nc3qzpvcvzfxru
P932PMC publication ID3438669
P698PubMed publication ID22628264
P5875ResearchGate publication ID225044200

P50authorWei TongQ59157758
P2093author name stringJing Zhang
Jing Jiang
Juan Du
Jinyong Wang
Jingfang Zhang
Guangyao Kong
Yangang Liu
P2860cites workLnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2Q28508573
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cellsQ29615006
Hematopoiesis: an evolving paradigm for stem cell biologyQ29619676
Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5.Q33853579
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factorsQ34152009
Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemiaQ34541588
Single cell profiling of potentiated phospho-protein networks in cancer cells.Q34549433
Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent mannerQ35112241
Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin.Q35800066
K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cellsQ35804477
Signals emanating from the membrane proximal region of the thrombopoietin receptor (mpl) support hematopoietic stem cell self-renewalQ36113963
Bone-marrow haematopoietic-stem-cell nichesQ36402226
The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cellsQ36585519
Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulationQ37059643
Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU.Q37079677
Thrombopoietin expands hematopoietic stem cells after transplantationQ39738286
Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche.Q39997716
Expansion of human cord blood hematopoietic stem cells for transplantationQ41976345
IFNalpha activates dormant haematopoietic stem cells in vivo.Q44358922
Role of c-mpl in early hematopoiesis.Q47929597
CD44-deficient mice develop normally with changes in subpopulations and recirculation of lymphocyte subsets.Q52173790
Critical Role of Thrombopoietin in Maintaining Adult Quiescent Hematopoietic Stem CellsQ57362319
Cytokine receptor expression on hematopoietic stem and progenitor cellsQ71933593
P433issue7
P304page(s)1447-1454
P577publication date2012-07-01
P1433published inStem CellsQ15724411
P1476titleSignaling profiling at the single-cell level identifies a distinct signaling signature in murine hematopoietic stem cells
P478volume30

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cites work (P2860)
Q33685977Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm
Q42315227Kras is Required for Adult Hematopoiesis
Q35320335Measuring and sorting cell populations expressing isospectral fluorescent proteins with different fluorescence lifetimes
Q36962687Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions
Q36309523Oncogenic NRAS hyper-activates multiple pathways in human cord blood stem/progenitor cells and promotes myelomonocytic proliferation in vivo
Q38672557Single-cell analyses to reveal hematopoietic stem cell fate decisions
Q64088176The autophagy Protein Plays a Crucial Role in the Maintenance and Reconstitution Ability of Hematopoietic Stem Cells
Q35743835Thrombopoietin promotes NHEJ DNA repair in hematopoietic stem cells through specific activation of Erk and NF-κB pathways and their target, IEX-1

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