Low molecular weight fucoidan ameliorates diabetic nephropathy via inhibiting epithelial-mesenchymal transition and fibrotic processes

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Low molecular weight fucoidan ameliorates diabetic nephropathy via inhibiting epithelial-mesenchymal transition and fibrotic processes is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID4626417
P698PubMed publication ID26550455

P2093author name stringYi Sun
Hong Zhou
Lin Weng
Quanbin Zhang
Baoxue Yang
Dali Luo
Jihui Chen
Yingli Jia
Wentong Cui
P2860cites workDual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transitionQ24305416
MicroRNAs in kidney fibrosis and diabetic nephropathy: roles on EMT and EndMTQ26851458
Role of the TGF-β/BMP-7/Smad pathways in renal diseasesQ28278757
Evidence that fibroblasts derive from epithelium during tissue fibrosisQ29616581
The protective effect of fucoidan in rats with streptozotocin-induced diabetic nephropathyQ33808925
Molecular basis of renal fibrosisQ34125332
Low molecular weight fucoidan against renal ischemia-reperfusion injury via inhibition of the MAPK signaling pathwayQ34589918
Low-molecular-weight fucoidan protects endothelial function and ameliorates basal hypertension in diabetic Goto-Kakizaki ratsQ35116260
The role of epithelial-to-mesenchymal transition in renal fibrosisQ35643525
TGF-beta-induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healingQ35841836
Transcriptional regulation of cadherins during development and carcinogenesis.Q35878878
Genetic programs of epithelial cell plasticity directed by transforming growth factor-betaQ36232185
Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3' kinase/AKT pathwaysQ36313178
Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transitionQ36321284
Fucoidan partly prevents CCl4-induced liver fibrosisQ36482392
Signaling cross-talk between TGF-beta/BMP and other pathwaysQ37323342
Transcriptional regulation of cell polarity in EMT and cancerQ37333606
TGF-beta1-induced epithelial-to-mesenchymal transition and therapeutic intervention in diabetic nephropathy.Q37627056
Diabetic nephropathy in 2010: Alleviating the burden of diabetic nephropathyQ37833489
Fibroblasts and myofibroblasts in renal fibrosisQ37847632
Paracrine role for TGF-β-induced CTGF and VEGF in mesangial matrix expansion in progressive glomerular diseaseQ38027100
Fucoidan induces changes in the epithelial to mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGFβ receptor degradation in breast cancer.Q39218826
TGFβ modulates cell-to-cell communication in early epithelial-to-mesenchymal transitionQ39418101
Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transitionQ40120833
Effects of fucoidan on chronic renal failure in ratsQ44515101
Alpha-amylase and alpha-glucosidase inhibition is differentially modulated by fucoidan obtained from Fucus vesiculosus and Ascophyllum nodosumQ46951463
Attenuation of streptozotocin-induced diabetic retinopathy with low molecular weight fucoidan via inhibition of vascular endothelial growth factorQ47226139
Low molecular weight fucoidan improves endoplasmic reticulum stress-reduced insulin sensitivity through AMP-activated protein kinase activation in L6 myotubes and restores lipid homeostasis in a mouse model of type 2 diabetesQ47236254
The kidney in diabetes: dynamic pathways of injury and repair. The Camillo Golgi Lecture 2007.Q48552318
Effect of fucoidan administration on insulin secretion and insulin resistance in overweight or obese adults.Q51325986
Fucoidan regulate blood glucose homeostasis in C57BL/KSJ m+/+db and C57BL/KSJ db/db mice.Q51356882
Connective Tissue Growth Factor Expressed in Tubular Epithelium Plays a Pivotal Role in Renal FibrogenesisQ57691320
Development of diabetes in the non-obese NIDDM rat (GK rat)Q70264384
The emerging role of transforming growth factor-beta in kidney diseasesQ72043105
Association of prolonged hyperglycemia with glomerular hypertrophy and renal basement membrane thickening in the Goto Kakizaki model of non-insulin-dependent diabetes mellitusQ73396325
Effect and mechanism of fucoidan derivatives from Laminaria japonica in experimental adenine-induced chronic kidney diseaseQ83158832
Suppression by fucoidan of liver fibrogenesis via the TGF-β/Smad pathway in protecting against oxidative stressQ84150886
Mechanisms of tubulointerstitial fibrosisQ85074102
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectdiabetic nephropathyQ1129105
P304page(s)1553-1563
P577publication date2015-09-15
P1433published inAmerican Journal of Translational ResearchQ4744272
P1476titleLow molecular weight fucoidan ameliorates diabetic nephropathy via inhibiting epithelial-mesenchymal transition and fibrotic processes
P478volume7

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cites work (P2860)
Q33612287Efficacy of Low-Molecular-Weight Fucoidan as a Supplemental Therapy in Metastatic Colorectal Cancer Patients: A Double-Blind Randomized Controlled Trial
Q26739976Fucoidans in Nanomedicine
Q37193130Low molecular weight fucoidan protects renal tubular cells from injury induced by albumin overload
Q64111682Low-molecular-weight fucoidan attenuates bleomycin-induced pulmonary fibrosis: possible role in inhibiting TGF-β1-induced epithelial-mesenchymal transition through ERK pathway
Q41066153Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression.
Q89975396Protective Effect of Low-Molecular-Weight Fucoidan on Radiation-Induced Fibrosis Through TGF-β1/Smad Pathway-Mediated Inhibition of Collagen I Accumulation

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