The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions

scientific article

The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1042/CS20040370
P698PubMed publication ID16104843

P2093author name stringMasabumi Shibuya
Hiroyuki Takahashi
P2860cites workRegulation of endothelium-derived nitric oxide production by the protein kinase AktQ22010149
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylationQ22010150
VEGF-D promotes the metastatic spread of tumor cells via the lymphaticsQ28200072
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectendotheliumQ111140
P304page(s)227-241
P577publication date2005-09-01
P1433published inClinical ScienceQ372419
P1476titleThe vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
P478volume109

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cites work (P2860)
Q27023870A Comprehensive and System Review for the Pharmacological Mechanism of Action of Rhein, an Active Anthraquinone Ingredient
Q36706461A Meta-Analysis of Studies Evaluating Visual and Anatomical Outcomes in Patients with Treatment Resistant Neovascular Age-Related Macular Degeneration following Switching to Treatment with Aflibercept
Q30439884A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap
Q38561314A placenta growth factor 2 variant acts as dominant negative of vascular endothelial growth factor A by heterodimerization mechanism.
Q30433214A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use.
Q37400451ALS and oxidative stress: the neurovascular scenario
Q37419632Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
Q39385904Activation of Dengue Virus-Specific T Cells Modulates Vascular Endothelial Growth Factor Receptor 2 Expression
Q30479159Adult stem cells and their trans-differentiation potential--perspectives and therapeutic applications
Q38049556Aflibercept for intravitreal injection: in neovascular age-related macular degeneration
Q91863172Alkaloid extract of Corydalis yanhusuo inhibits angiogenesis via targeting vascular endothelial growth factor receptor signaling
Q37287612An ezrin/calpain/PI3K/AMPK/eNOSs1179 signaling cascade mediating VEGF-dependent endothelial nitric oxide production
Q33689582Anchorage of VEGF to the extracellular matrix conveys differential signaling responses to endothelial cells
Q37330675Angiogenesis and lymphangiogenesis are downregulated in primary breast cancer
Q36268680Angiogenesis in implantation
Q37645436Angiogenesis in the atherosclerotic plaque.
Q38130312Angiogenesis inhibitors in cancer therapy: mechanistic perspective on classification and treatment rationales
Q36928129Angiogenic factors and their soluble receptors predict organ dysfunction and mortality in post-cardiac arrest syndrome
Q45884628Angiogenic gene-modified myoblasts promote vascularization during repair of skeletal muscle defects
Q52151011Anti-Vascular Endothelial Growth Factor Treatment Suppresses Early Brain Injury After Subarachnoid Hemorrhage in Mice.
Q33713224Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice
Q45405723Antimicrobial peptide LL37 promotes vascular endothelial growth factor-A expression in human periodontal ligament cells
Q39519501Antivascular endothelial growth factor agents for neovascular age-related macular degeneration
Q42323537Aspalatone Prevents VEGF-Induced Lipid Peroxidation, Migration, Tube Formation, and Dysfunction of Human Aortic Endothelial Cells
Q36638595Association of -2549 insertion/deletion polymorphism of vascular endothelial growth factor with breast cancer in North Indian patients.
Q92680818Association of VEGFA and IL1β gene polymorphisms with preeclampsia in Sudanese women
Q37660950Association of a vascular endothelial growth factor polymorphism with the development of bronchopulmonary dysplasia in Japanese premature newborns
Q93067565Association study between the polymorphisms of angiogenesis-related genes and cervical cancer susceptibility in Chinese Uygur population
Q35049491Attenuation of VEGFR-2 expression by sFlt-1 and low oxygen in human placenta
Q64951363Behavior of Smooth Muscle Cells under Hypoxic Conditions: Possible Implications on the Varicose Vein Endothelium.
Q45919219Bevacizumab versus ranibizumab in the treatment of exudative age-related macular degeneration.
Q42139247Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
Q38159735Bioactive lipids in pathological retinopathy
Q90155964Biochemical and Conformational Characterization of Recombinant VEGFR2 Domain 7
Q38604899Biodegradable Carriers for Delivery of VEGF Plasmid DNA for the Treatment of Critical Limb Ischemia
Q38003860Biological, preclinical and clinical characteristics of inhibitors of vascular endothelial growth factors.
Q59808726Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients
Q34695003Biomarkers for anti-angiogenic therapy in cancer.
Q37695245Blockade of vascular endothelial growth factor receptors by tivozanib has potential anti-tumour effects on human glioblastoma cells
Q34124396Blocking autocrine VEGF signaling by sunitinib, an anti-cancer drug, promotes embryonic stem cell self-renewal and somatic cell reprogramming
Q46433721Blood vessel formation during tail regeneration in the leopard gecko (Eublepharis macularius): The blastema is not avascular.
Q26826870Brain homeostasis: VEGF receptor 1 and 2-two unequal brothers in mind
Q51356864Branched-chain amino acid deficiency stabilizes insulin-induced vascular endothelial growth factor mRNA in hepatocellular carcinoma cells.
Q38056776Bronchoalveolar hemostasis in lung injury and acute respiratory distress syndrome
Q37706317CCL24 contributes to HCC malignancy via RhoB- VEGFA-VEGFR2 angiogenesis pathway and indicates poor prognosis
Q43061600Cardiovascular disease complications in systemic lupus erythematosus
Q39918362Catalyser-21(TM), a mineral water derived from leaf soil, inhibits tumor cell invasion and angiogenesis
Q57937606Celiac disease IgA modulates vascular permeability in vitro through the activity of transglutaminase 2 and RhoA
Q42044273Cellular and molecular mechanisms involved in the neuroprotective effects of VEGF on motoneurons.
Q37461446Changes in vascular endothelial growth factor (VEGF) induced by the Morris water maze task
Q33317046Cheiradone: a vascular endothelial cell growth factor receptor antagonist.
Q33894658Cholecystokinin mediates progression and metastasis of pancreatic cancer associated with dietary fat.
Q37156639Circulating lymphangiogenic growth factors in gastrointestinal solid tumors, could they be of any clinical significance?
Q53655244Clinical efficacy of metronomic chemotherapy after cool-tip radiofrequency ablation in the treatment of hepatocellular carcinoma.
Q37961087Clinical implications of genetic variations in the VEGF system in relation to colorectal cancer.
Q39757470Cloning and expression of human vascular endothelial growth factor gene and inhibition of its expression by antisense in prokaryotic system.
Q38261105Complications of subspecialty ophthalmic care: systemic complications from the intravitreal administration of agents that target the vascular endothelial growth factor pathway.
Q92756232Compound C Inhibits B16-F1 Tumor Growth in a Syngeneic Mouse Model Via the Blockage of Cell Cycle Progression and Angiogenesis
Q90699218Comprehensive review of targeted therapy for colorectal cancer
Q30436024Computational kinetic model of VEGF trapping by soluble VEGF receptor-1: effects of transendothelial and lymphatic macromolecular transport
Q92541892Contribution of Angiogenesis to Inflammation and Cancer
Q33742723Cyclic stretch, reactive oxygen species, and vascular remodeling
Q91782048Defining the Inflammatory Microenvironment in the Human Cochlea by Perilymph Analysis: Toward Liquid Biopsy of the Cochlea
Q51830776Development of CE methods to analyze potential components of the angiogenic glycoprotein vascular endothelial growth factor 165.
Q42024507Development of a CE-MS method to analyze components of the potential biomarker vascular endothelial growth factor 165.
Q42406987Dextran sulfate sodium leads to chronic colitis and pathological angiogenesis in endoglin heterozygous mice
Q38542115Diabetic Retinopathy: Vascular and Inflammatory Disease.
Q89782757Differential Secretion of Angiopoietic Factors and Expression of MicroRNA in Umbilical Cord Blood from Healthy Appropriate-For-Gestational-Age Preterm and Term Newborns-in Search of Biomarkers of Angiogenesis-Related Processes in Preterm Birth
Q42030071Differential apicobasal VEGF signaling at vascular blood-neural barriers
Q34201006Differential expression of Vegfr-2 and its soluble form in preeclampsia
Q42132535Differential regulation of VEGF signaling by PKC-alpha and PKC-epsilon in endothelial cells
Q64989146Direct measurements of VEGF-VEGFR2 binding affinities reveal the coupling between ligand binding and receptor dimerization.
Q39584429Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potency in the acute myelogenous leukemia-Flt-3-internal tandem duplication mutant human tumor xenograft model.
Q46527823Distinct signaling pathways confer different vascular responses to VEGF 121 and VEGF 165.
Q34616563Effect of VEGF and VEGF Trap on vascular endothelial cell signaling in tumors
Q48261041Effect of intravitreal aflibercept (Eylea(®)) on retrobulbar hemodynamics in patients with neovascular age-related macular degeneration.
Q49667627Effects of Intravitreal Aflibercept on Galectin-1 and Vascular Endothelial Growth Factor-A Plasma Levels in Patients with Diabetic Retinopathy
Q43052752Effects of resveratrol on expression of vascular endothelial growth factor in human gingival fibroblasts stimulated by periodontal pathogens
Q38020128Effects of vascular endothelial growth factor in ischemic stroke
Q38304000Electroacupuncture suppresses myostatin gene expression: cell proliferative reaction in mouse skeletal muscle
Q64374719Endothelial FAM3A positively regulates post-ischaemic angiogenesis
Q37680222Endothelial and smooth muscle cells derived from human cardiac explants demonstrate angiogenic potential and suitable for design of cell-containing vascular grafts.
Q39924560Endotoxin-induced HIF-1alpha stabilisation in equine endothelial cells: synergistic action with hypoxia
Q34787415Engineered conformation-dependent VEGF peptide mimics are effective in inhibiting VEGF signaling pathways
Q37356898Evaluation of antiangiogenic and antiproliferative potential of the organic extract of green algae Chlorella pyrenoidosa
Q40745908Evaluation of circulating vascular endothelial growth factor and its soluble receptors in patients suffering from persistent allergic rhinitis
Q38795614Exosomes in stroke pathogenesis and therapy
Q90198339Expression and characterization of recombinant human VEGF165 in the middle silk gland of transgenic silkworms
Q46647666Expression of VEGF-A/C, VEGF-R2, PDGF-alpha/beta, c-kit, EGFR, Her-2/Neu, Mcl-1 and Bmi-1 in Merkel cell carcinoma
Q33611056Expression of growth factor receptors and targeting of EGFR in cholangiocarcinoma cell lines
Q39958821Expression of vascular endothelial growth factor (VEGF)-B and its receptor (VEGFR1) in murine heart, lung and kidney
Q37267837Expressions of VEGF-A and VEGFR-2 in placentae from GDM pregnancies
Q59792865Extracellular Protein Fibulin-7 and Its C-Terminal Fragment Have In Vivo Antiangiogenic Activity
Q43239279Fetal adrenal gland alterations in a rat model of adverse intrauterine environment
Q50541802Gene delivery of soluble vascular endothelial growth factor receptor-1 (sFlt-1) inhibits intra-plaque angiogenesis and suppresses development of atherosclerotic plaque
Q38654588Gene therapy for age-related macular degeneration.
Q58362653Gene therapy in peripheral artery disease
Q55452882Gene-Therapeutic Strategies Targeting Angiogenesis in Peripheral Artery Disease.
Q83715974Genetic variants on chromosome 6p21.1 and 6p22.3 are associated with type 2 diabetes risk: a case-control study in Han Chinese
Q35912389Genetic variation in VEGF family genes and breast cancer risk: a report from the Shanghai Breast Cancer Genetics Study
Q41423380Genome-wide expression differences in anti-Vegf and dexamethasone treatment of inflammatory angiogenesis in the rat cornea.
Q34335643Gram-positive pathogenic bacteria induce a common early response in human monocytes
Q37676697Growth factors as active participants in carcinogenesis: a perspective
Q46819215Helical peptides from VEGF and Vammin hotspots for modulating the VEGF-VEGFR interaction.
Q36524769Heparanase regulates in vitro VEGF-C expression and its clinical significance to pancreatic ductal cell adenocarcinoma
Q37398294Heterozygous disruption of Flk-1 receptor leads to myocardial ischaemia reperfusion injury in mice: application of affymetrix gene chip analysis
Q54631831Hippocampal Neurogenesis after Traumatic Brain Injury Is Mediated by Vascular Endothelial Growth Factor Receptor-2 and the Raf/MEK/ERK Cascade
Q36431941How useful is the assessment of lymphatic vascular density in oral carcinoma prognosis?
Q43713556Human mature endothelial cells modulate peripheral blood mononuclear cell differentiation toward an endothelial phenotype.
Q91522755Hydrostatic pressure promotes endothelial tube formation through aquaporin 1 and Ras-ERK signaling
Q81892999Immunoexpression of vascular endothelial growth factor in periapical granulomas, radicular cysts, and residual radicular cysts
Q45905279Immunohistochemical correlation between microvessel density and lymphoid infiltrate in radicular cysts.
Q41852551Immunohistochemical expression of vascular endothelial growth factor and matrix metalloproteinase-9 in radicular and residual radicular cysts
Q35628369Increased expression of vascular endothelial growth factor in neo-vascularized canine brain tissue
Q36394290Increased plasma concentration of vascular endothelial growth factor in patients with atopic dermatitis and its relation to disease severity and platelet activation
Q35089453Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes
Q48581073Influence of vascular endothelial growth factor and Cysteamine on in vitro bovine oocyte maturation and subsequent embryo development.
Q36764876Inhibiting kinases in malignant gliomas
Q37031073Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function
Q45783799Inhibition of p38 MAPK reduces expression of vascular endothelial growth factor in allergic airway disease
Q39594949Inhibitory effect of curcumin on oral carcinoma CAL-27 cells via suppression of Notch-1 and NF-κB signaling pathways
Q30437740Interactions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapy
Q38591546Intercellular communication lessons in heart failure
Q36918194Intracrine VEGF Signaling Mediates the Activity of Prosurvival Pathways in Human Colorectal Cancer Cells.
Q41902127Intravitreal injection of ranibizumab and CTGF shRNA improves retinal gene expression and microvessel ultrastructure in a rodent model of diabetes
Q37135388Intravitreous anti-VEGF for diabetic retinopathy: hopes and fears for a new therapeutic strategy
Q35145097Involvement of Flt-1 (VEGF receptor-1) in cancer and preeclampsia
Q42415885Ischemia-reperfusion injury induces occludin phosphorylation/ubiquitination and retinal vascular permeability in a VEGFR-2-dependent manner
Q39415018KMUP-1 inhibits H441 lung epithelial cell growth, migration and proinflammation via increased NO/CGMP and inhibited RHO kinase/VEGF signaling pathways
Q34552843KRIT1 protein depletion modifies endothelial cell behavior via increased vascular endothelial growth factor (VEGF) signaling
Q26822766Keratinocytic vascular endothelial growth factor as a novel biomarker for pathological skin condition
Q38008362Key Features of the Intragraft Microenvironment that Determine Long-Term Survival Following Transplantation
Q35760920Knockdown of VEGF receptor-1 (VEGFR-1) impairs macrophage infiltration, angiogenesis and growth of clear cell renal cell carcinoma (CRCC).
Q51838560Kolaviron improved resistance to oxidative stress and inflammation in the blood (erythrocyte, serum, and plasma) of streptozotocin-induced diabetic rats.
Q46061181L-Arginine promotes angiogenesis in the chronically hypoxic lung: a novel mechanism ameliorating pulmonary hypertension.
Q34338215Malignant pericardial effusion
Q42080378Mast Cell-Intervertebral disc cell interactions regulate inflammation, catabolism and angiogenesis in Discogenic Back Pain
Q35716176Maternal Smoking History Enhances the Expression of Placental Growth Factor in Invasive Trophoblasts at Early Gestation Despite Cessation of Smoking
Q46928117Matrix metalloproteinases and vascular endothelial growth factor expression in canine leukaemias
Q38953207Mechanical forces induce changes in VEGF and VEGFR-1/sFlt-1 expression in human chondrocytes.
Q37956587Mechanisms of resistance to vascular endothelial growth factor blockade
Q37678807Mediators of ocular angiogenesis
Q37236004Metronomic chemotherapy: possible clinical application in advanced hepatocellular carcinoma
Q28395657MiR-590-5p inhibits colorectal cancer angiogenesis and metastasis by regulating nuclear factor 90/vascular endothelial growth factor A axis
Q38874739Microvascular density and immunohistochemical expression of VEGF, VEGFR-1 and VEGFR-2 in benign prostatic hyperplasia, high-grade prostate intraepithelial neoplasia and prostate cancer
Q41847558Modified rice bran hemicellulose inhibits vascular endothelial growth factor-induced angiogenesis in vitro via VEGFR2 and its downstream signaling pathways
Q36710448Modulation of vascular endothelial growth factor (VEGF) expression in motor neurons and its electrophysiological effects
Q50423780Molecular Regulation of Sprouting Angiogenesis
Q42121924Molecular and clinical aspects of targeting the VEGF pathway in tumors.
Q34566028Molecular and functional diversity of vascular endothelial growth factors
Q34089123Molecular diversity of VEGF-A as a regulator of its biological activity.
Q36279449Morphological Plasticity of Emerging Purkinje Cells in Response to Exogenous VEGF
Q38304336NKCC1 mediates traumatic brain injury-induced hippocampal neurogenesis through CREB phosphorylation and HIF-1α expression.
Q33921294NKX2-3 transcriptional regulation of endothelin-1 and VEGF signaling in human intestinal microvascular endothelial cells
Q41825489Nanoglycan complex formulation extends VEGF retention time in the lung
Q90469422Network Pharmacology Analysis of Traditional Chinese Medicine Formula Xiao Ke Yin Shui Treating Type 2 Diabetes Mellitus
Q43458281Neuroprotective effect of melatonin against hypoxia-induced retinal ganglion cell death in neonatal rats
Q34474159New Insights into VEGF-A Alternative Splicing: Key Regulatory Switching in the Pathological Process
Q38308502Non-competitive aptamer-based quenching resonance energy transfer assay for homogeneous growth factor quantification.
Q34947216Novel VEGF decoy receptor fusion protein conbercept targeting multiple VEGF isoforms provide remarkable anti-angiogenesis effect in vivo
Q58800992Onset and Progression of Human Osteoarthritis-Can Growth Factors, Inflammatory Cytokines, or Differential miRNA Expression Concomitantly Induce Proliferation, ECM Degradation, and Inflammation in Articular Cartilage?
Q100490609Overview of current targeted therapy in gallbladder cancer
Q42437368Parathyroid hormone-related protein interacts with vascular endothelial growth factor to promote fibrogenesis in the obstructed mouse kidney
Q39258872Pathogenesis of vascular leak in dengue virus infection
Q42369962Pathogenic CD8+ T Cells Cause Increased Levels of VEGF-A in Experimental Malaria-Associated Acute Respiratory Distress Syndrome, but Therapeutic VEGFR Inhibition Is Not Effective
Q26865897Pathophysiology of diabetic retinopathy
Q30437439Paxillin is involved in the differential regulation of endothelial barrier by HGF and VEGF.
Q47803418Pediatric brain repair from endogenous neural stem cells of the subventricular zone
Q39468924Perfluorocarbon emulsions prevent hypoxia of pancreatic β-cells.
Q37828119Pigment epithelium-derived factor as an impending therapeutic agent against vascular epithelial growth factor-driven tumor-angiogenesis.
Q35884170Placental Underperfusion in a Rat Model of Intrauterine Growth Restriction Induced by a Reduced Plasma Volume Expansion
Q53093520Platelet-Rich Plasma in a Murine Model: Leukocytes, Growth Factors, Flt-1, and Muscle Healing.
Q92070082Platelet-rich plasma as a site-targeted approach in wound healing: a molecular perspective
Q41473406Poly-γ-glutamic acid attenuates angiogenesis and inflammation in experimental colitis.
Q33646077Prognostic Value of Vascular Endothelial Growth Factor A in the Prediction of the Tumor Aggressiveness in Clear Cell Renal Cell Carcinoma
Q35480244Prognostic role of vascular endothelial growth factor in prostate cancer: a systematic review and meta-analysis
Q36894556Progress in defining the molecular biology of age related macular degeneration
Q36787218Promise of multiphoton detection in discovery and diagnostic proteomics
Q55386583Prostaglandin F-2α Stimulates The Secretion of Vascular Endothelial Growth Factor and Induces Cell Proliferation and Migration of Adipose Tissue Derived Mesenchymal Stem Cells.
Q38094076Ranibizumab: a review of its use in the treatment of neovascular age-related macular degeneration
Q36627279Ranibizumab: treatment in patients with neovascular age-related macular degeneration
Q53576295Rapid onset of gene expression in lung, supportive of formation of alveolar septa, induced by refeeding mice after calorie restriction.
Q91239698Real-time in vivo two-photon imaging study reveals decreased cerebro-vascular volume and increased blood-brain barrier permeability in chronically stressed mice
Q37760097Recent concepts of antiangiogenic therapy
Q26751331Recent developments in receptor tyrosine kinases targeted anticancer therapy
Q39456719Regulation of Vegf signaling by natural and synthetic ligands
Q99605264Resveratrol and Tumor Microenvironment: Mechanistic Basis and Therapeutic Targets
Q34525985Role of receptor tyrosine kinase transmembrane domains in cell signaling and human pathologies
Q38212662Roles of VEGF-A signalling in development, regeneration, and tumours
Q47116461Roles of VEGF-Flt-1 signaling in malignant behaviors of oral squamous cell carcinoma.
Q33616384Roles of vascular endothelial growth factor in amyotrophic lateral sclerosis
Q38734446Selective Imaging of VEGFR-1 and VEGFR-2 Using 89Zr-Labeled Single-Chain VEGF Mutants.
Q40144966Selective inhibition of plasma membrane calcium ATPase 4 improves angiogenesis and vascular reperfusion
Q24617241Semaphorin-PlexinD1 signaling limits angiogenic potential via the VEGF decoy receptor sFlt1
Q48545238Serum VEGF levels in acute ischaemic strokes are correlated with long-term prognosis
Q55011252Serum VEGF levels in the early diagnosis and severity assessment of non-small cell lung cancer.
Q36956283Serum level of vascular endothelial growth factor decreased in chronic ketamine abusers
Q89495793Sevoflurane promotes the proliferation of HUVECs by activating VEGF signaling
Q64991000SiRNA silencing of VEGF, IGFs, and their receptors in human retinal microvascular endothelial cells.
Q59381645Sjögren’s syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-κB
Q63990343Smad signal pathway regulates angiogenesis via endothelial cell in an adipose-derived stromal cell/endothelial cell co-culture, 3D gel model
Q54648907Soluble receptors for vascular endothelial growth factor (sVEGFR1/sVEGFR2) in infantile hemangioma
Q39126237Statins in conditions other than hypocholesterolemic effects for chronic subdural hematoma therapy, old drug, new tricks?
Q33434180Stilbene glycosides are natural product inhibitors of FGF-2-induced angiogenesis.
Q28487616Structural characterization of a recombinant fusion protein by instrumental analysis and molecular modeling
Q90450692Study on the correlation and predictive value of serum pregnancy-associated plasma protein A, triglyceride and serum 25-hydroxyvitamin D levels with gestational diabetes mellitus
Q34798203Substantial neuroprotection against K+ deprivation-induced apoptosis in primary cerebellar granule neurons by novel dimer bis(propyl)-cognitin via the activation of VEGFR-2 signaling pathway
Q35783198Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity
Q36200700Systematic evaluation of natural scaffolds in cutaneous wound healing
Q34452811Systemic safety of anti-VEGF drugs: a commentary
Q38032311Systemic thromboembolic adverse events in patients treated with intravitreal anti-VEGF drugs for neovascular age-related macular degeneration
Q38210239Systemic thromboembolic adverse events in patients treated with intravitreal anti-VEGF drugs for neovascular age-related macular degeneration: an overview.
Q30438979Systems biology of vascular endothelial growth factors
Q35815609TGFβ signalling pathway regulates angiogenesis by endothelial cells, in an adipose-derived stromal cell/endothelial cell co-culture 3D gel model
Q46621277TNF-α and LPS activate angiogenesis via VEGF and SIRT1 signalling in human dental pulp cells
Q60047642TRP Channels in Angiogenesis and Other Endothelial Functions
Q55128284Targeting Splicing in Prostate Cancer.
Q33387704The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer
Q97547928The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
Q54636138The Bartonella henselae VirB/Bep system interferes with vascular endothelial growth factor (VEGF) signalling in human vascular endothelial cells.
Q36144280The JAK/STAT3 signalling pathway regulated angiogenesis in an endothelial cell/adipose-derived stromal cell co-culture, 3D gel model.
Q55398453The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model.
Q37636781The VEGF rise in blood of bevacizumab patients is not based on tumor escape but a host-blockade of VEGF clearance.
Q35647966The adaptation of the blood-brain barrier to vascular endothelial growth factor and placental growth factor during pregnancy
Q39787486The balance of autocrine VEGF-A and VEGF-C determines podocyte survival
Q26796921The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis
Q34245619The discovery of placenta growth factor and its biological activity.
Q44309209The dynamics of angiogenic factors and their soluble receptors in relation to organ dysfunction in disseminated intravascular coagulation associated with sepsis
Q38103868The effect of vascular endothelial growth factor in the progression of bladder cancer and diabetic retinopathy
Q35501083The effect of vascular endothelial growth factor on osteoclastogenesis in rheumatoid arthritis
Q80517364The immunohistochemical analysis of vascular endothelial growth factors A and C and microvessel density in gingival tissues of systemic sclerosis patients: their possible effects on gingival inflammation
Q84880225The importance of -460 C/T and +405 G/C single nucleotide polymorphisms to the function of vascular endothelial growth factor A in colorectal cancer
Q37263382The osteogenic-angiogenic interface: novel insights into the biology of bone formation and fracture repair
Q37334240The prognostic value of haplotypes in the vascular endothelial growth factor a gene in colorectal cancer
Q36390431The role of VEGF receptors in angiogenesis; complex partnerships
Q48895465The role of VEGF/VEGFR2 signaling in peripheral stimulation-induced cerebral neurovascular regeneration after ischemic stroke in mice
Q26798348The role of aflibercept in the management of diabetic macular edema
Q36616721The role of angiogenic factors and their soluble receptors in acute lung injury (ALI)/ acute respiratory distress syndrome (ARDS) associated with critical illness
Q100523503The role of the PlGF/Flt-1 signaling pathway in the cardiorenal connection
Q37418939The role of vascular endothelial growth factor in metastatic prostate cancer to the skeleton
Q35618768Therapeutic Angiogenesis by Gene Therapy for Critical Limb Ischemia: Choice of Biological Agent
Q39731093Therapeutic angiogenesis by transplantation of human embryonic stem cell-derived CD133+ endothelial progenitor cells for cardiac repair
Q42115589Thrombin-induced VEGF expression in human retinal pigment epithelial cells
Q37718435Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in multiple myeloma xenograft mouse model
Q42548913Time-dependent changes of plasma concentrations of angiopoietins, vascular endothelial growth factor, and soluble forms of their receptors in nonsmall cell lung cancer patients following surgical resection
Q37420851Transcriptional profiling of hilar nodes from pigs after experimental infection with Actinobacillus pleuropneumoniae
Q27329613Transmigration of neural stem cells across the blood brain barrier induced by glioma cells
Q37233230Treatment of age-related macular degeneration: focus on ranibizumab
Q42864506Tyrosine phosphorylation modulates the vascular responses of mesenteric arteries from human colorectal tumors.
Q36925848Using angiogenic factors and their soluble receptors to predict organ dysfunction in patients with disseminated intravascular coagulation associated with severe trauma
Q38681382VEGF Expression in Pancreatic Cancer and Other Malignancies: A Review of the Literature
Q92409844VEGF Induce Vasculogenic Mimicry of Choroidal Melanoma through the PI3k Signal Pathway
Q35980480VEGF Receptor-2-Linked PI3K/Calpain/SIRT1 Activation Mediates Retinal Arteriolar Dilations to VEGF and Shear Stress
Q39910127VEGF and Bcl-2 interact via MAPKs signaling pathway in the response to hypoxia in neuroblastoma
Q42099822VEGF and Notch in tip and stalk cell selection
Q30432040VEGF and soluble VEGF receptor-1 (sFlt-1) distributions in peripheral arterial disease: an in silico model
Q36485145VEGF is differentially regulated in multiple myeloma-derived cell lines by norepinephrine
Q100415976VEGF knockdown enhances radiosensitivity of nasopharyngeal carcinoma by inhibiting autophagy through the activation of mTOR pathway
Q37848687VEGF non-angiogenic functions in adult organ homeostasis: therapeutic implications
Q81326073VEGF receptor inhibition slows the progression of polycystic kidney disease
Q29617256VEGF receptor signalling - in control of vascular function
Q45257013VEGF-B Levels in the Vitreous of Diabetic and Non-Diabetic Patients with Ocular Diseases and Its Correlation with Structural Parameters
Q39519666VEGF-C differentially regulates VEGF-A expression in ocular and cancer cells; promotes angiogenesis via RhoA mediated pathway
Q41900132VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2
Q91405026VEGF/Flk1 Mechanism is Involved in Roxarsone Promotion of Rat Endothelial Cell Growth and B16F10 Xenograft Tumor Angiogenesis
Q37397851VEGFR-1 regulates adult olfactory bulb neurogenesis and migration of neural progenitors in the rostral migratory stream in vivo
Q36791927VEGFR-2 conformational switch in response to ligand binding.
Q55021686Vascular Endothelial Growth Factor Gene Polymorphism Is Associated With Long-term Kidney Allograft Outcomes.
Q42950906Vascular endothelial growth factor (VEGF) and VEGF-receptor expression in placenta of hyperglycemic pregnant women
Q35762769Vascular endothelial growth factor biology: clinical implications for ocular treatments
Q91362469Vascular endothelial growth factor enhances profibrotic activities through modulation of calcium homeostasis in human atrial fibroblasts
Q37010405Vascular endothelial growth factor in astroglioma stem cell biology and response to therapy
Q36929380Vascular endothelial growth factor in eye disease
Q83389364Vascular endothelial growth factor in malignant and benign pericardial effusion
Q34910747Vascular endothelial growth factor levels in gingival crevicular fluid before and after periodontal therapy
Q45990804Vascular endothelial growth factor mRNA expression and peritumoral edema in canine primary central nervous system tumors.
Q36400129Vascular endothelial growth factors and their inhibitors in ocular neovascular disorders
Q27028225Vitreous mediators in retinal hypoxic diseases
Q42234877Vulnerability of primary neurons derived from Tg2576 Alzheimer mice to oxygen and glucose deprivation: role of intraneuronal amyloid-β accumulation and astrocytes.
Q45931894[MMP- and FAP-mediated non-inflammation-related destruction of cartilage and bone in rheumatoid arthritis].
Q35539017mRNA expression of VEGF and its receptors in fallopian tubes of women with ectopic pregnancies
Q33802900miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer
Q39303204β-catenin involvement in arsenite-induced VEGF expression in neuroblastoma SH-SY5Y cells

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