Potent Functional Immunogenicity of Plasmodium falciparum Transmission-Blocking Antigen (Pfs25) Delivered with Nanoemulsion and Porous Polymeric Nanoparticles

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Potent Functional Immunogenicity of Plasmodium falciparum Transmission-Blocking Antigen (Pfs25) Delivered with Nanoemulsion and Porous Polymeric Nanoparticles is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11095-015-1743-X
P932PMC publication ID4628851
P698PubMed publication ID26113235
P5875ResearchGate publication ID279302228

P2093author name stringRajesh Kumar
Richard Graves
Nirbhay Kumar
Tarun Mandal
Dibyadyuti Datta
Geetha P Bansal
Grace Ledet
Shana Robinson
P2860cites workMalaria transmission blocked by immunisation with gametes of the malaria parasiteQ42979953
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The 230-kDa gamete surface protein of plasmodium falciparum is also a target for transmission-blocking antibodiesQ44146561
Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activityQ44156482
Crystallization and preliminary X-ray analysis of the Plasmodium vivax sexual stage 25 kDa protein Pvs25, a transmission-blocking vaccine candidate for malariaQ44159925
The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prismsQ44166687
Biodegradable microparticles with different release profiles: effect on the immune response after a single administration via intranasal and intramuscular routes.Q45812465
Effect of different ratios of high and low molecular weight PLGA blend on the characteristics of pentamidine microcapsulesQ47431902
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Helminth antigens modulate TLR-initiated dendritic cell activationQ81111451
Algae-produced Pfs25 elicits antibodies that inhibit malaria transmissionQ21134576
Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model.Q33217285
Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.Q33350210
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Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trialQ34043843
Development of a Pfs25-EPA malaria transmission blocking vaccine as a chemically conjugated nanoparticleQ34341570
Saccharomyces cerevisiae recombinant Pfs25 adsorbed to alum elicits antibodies that block transmission of Plasmodium falciparum.Q34548828
A plant-produced Pfs25 VLP malaria vaccine candidate induces persistent transmission blocking antibodies against Plasmodium falciparum in immunized miceQ35048518
Sustained high-titer antibody responses induced by conjugating a malarial vaccine candidate to outer-membrane protein complexQ35132063
Pfs230: from malaria transmission-blocking vaccine candidate toward functionQ35548285
Long-lasting and transmission-blocking activity of antibodies to Plasmodium falciparum elicited in mice by protein conjugates of Pfs25.Q35575993
Target antigens of transmission-blocking immunity on gametes of plasmodium falciparumQ36348052
Wheat germ cell-free system-based production of malaria proteins for discovery of novel vaccine candidatesQ36539678
Correctly folded Pfs48/45 protein of Plasmodium falciparum elicits malaria transmission-blocking immunity in miceQ36670217
Quantification of the force of nanoparticle-cell membrane interactions and its influence on intracellular trafficking of nanoparticlesQ36943309
Nanovehicular intracellular delivery systemsQ37058812
Control to elimination: implications for malaria researchQ37257297
Biodegradable polymeric nanoparticles based drug delivery systemsQ37603750
Potent malaria transmission-blocking antibody responses elicited by Plasmodium falciparum Pfs25 expressed in Escherichia coli after successful protein refoldingQ37713285
Nano-microparticles as immune adjuvants: correlating particle sizes and the resultant immune responsesQ37785952
Vaccine delivery: a matter of size, geometry, kinetics and molecular patternsQ37800358
Key roles of adjuvants in modern vaccinesQ38169040
Enhanced immune response after subcutaneous and oral immunization with biodegradable PLGA microspheresQ38549187
Biodegradation of PLA/GA polymers: increasing complexityQ40498395
Recombinant Pfs25 protein of plasmodium falciparum elicits malaria transmission-blocking immunity in experimental animalsQ42006764
Successful immunization against the sexual stages of Plasmodium gallinaceumQ42979860
P433issue12
P921main subjectnanoparticleQ61231
Plasmodium falciparumQ311383
P304page(s)3827-3836
P577publication date2015-06-26
P1433published inPharmaceutical ResearchQ7180737
P1476titlePotent Functional Immunogenicity of Plasmodium falciparum Transmission-Blocking Antigen (Pfs25) Delivered with Nanoemulsion and Porous Polymeric Nanoparticles
P478volume32

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cites work (P2860)
Q57295566A malaria vaccine adjuvant based on recombinant antigen binding to liposomes
Q90706801Immunogenic Evaluation of Ribosomal P-Protein Antigen P0, P1, and P2 and Pentameric Protein Complex P0-(P1-P2)2 of Plasmodium falciparum in a Mouse Model
Q39062396Impact of the Charge Ratio on the In Vivo Immunogenicity of Lipoplexes
Q36079818Nanovaccines for malaria using Plasmodium falciparum antigen Pfs25 attached gold nanoparticles
Q47251697Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity
Q26750929Recent Advances in Subunit Vaccine Carriers

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