The physiological impact of microRNA gene regulation in the retina

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The physiological impact of microRNA gene regulation in the retina is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00018-012-0976-7
P932PMC publication ID3443797
P698PubMed publication ID22460583
P5875ResearchGate publication ID223989352

P50authorKrzysztof PalczewskiQ6440188
Thomas R SundermeierQ125252138
P2860cites workmiRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifsQ24292787
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Dynamic Changes of microRNAs in the Eye during the Development of Experimental Autoimmune UveoretinitisQ54408802
MicroRNA-126 inhibits ischemia-induced retinal neovascularization via regulating angiogenic growth factorsQ84131082
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Dicer inactivation leads to progressive functional and structural degeneration of the mouse retinaQ35886487
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miR-124 acts through CoREST to control onset of Sema3A sensitivity in navigating retinal growth cones.Q36866554
Human gene therapy for RPE65 isomerase deficiency activates the retinoid cycle of vision but with slow rod kineticsQ36937189
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microRNA expression in the eyes and their significance in relation to functionsQ37345681
Rhythmic expression of microRNA-26a regulates the L-type voltage-gated calcium channel alpha1C subunit in chicken cone photoreceptorsQ37377684
New meaning in the message: noncoding RNAs and their role in retinal developmentQ37384876
MicroRNAs couple cell fate and developmental timing in retinaQ37432291
Strategies for retinal repair: cell replacement and regenerationQ37574374
Understanding how miRNAs post-transcriptionally regulate gene expressionQ37617992
Retinal light damage: mechanisms and protectionQ37642126
Roles of small regulatory RNAs in determining neuronal identityQ37721761
Applications of nanoparticles in ophthalmologyQ37786424
Anti-VEGF Compounds in the Treatment of Neovascular Age Related Macular DegenerationQ37795844
MicroRNAs in development and diseaseQ37899669
MicroRNA regulation by RNA-binding proteins and its implications for cancerQ37913018
Identification and characterization of microRNAs expressed in the mouse eye.Q38305443
Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administrationQ24627838
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Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAsQ24629589
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A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNAQ24630341
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicingQ24631683
Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegansQ24632455
Safety and efficacy of gene transfer for Leber's congenital amaurosisQ24634724
Human RPE65 gene therapy for Leber congenital amaurosis: persistence of early visual improvements and safety at 1 yearQ24634801
Argonaute HITS-CLIP decodes microRNA-mRNA interaction mapsQ24645826
HITS-CLIP yields genome-wide insights into brain alternative RNA processingQ24648963
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Mammalian mirtron genesQ24652239
An ENU-induced mutation of miR-96 associated with progressive hearing loss in miceQ24652844
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer modelQ24655262
Intronic microRNA precursors that bypass Drosha processingQ24656618
The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS developmentQ24674190
MicroRNA-restricted transgene expression in the retinaQ27332143
Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplexQ27653175
Combinatorial microRNA target predictionsQ27860510
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegansQ27860584
An extensive class of small RNAs in Caenorhabditis elegansQ27860626
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Q27860849
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegansQ27860895
Identification of novel genes coding for small expressed RNAsQ27860917
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNAQ27861092
Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trialQ28262431
Correlation of overexpression of HMGA1 and HMGA2 with poor tumor differentiation, invasion, and proliferation associated with let-7 down-regulation in retinoblastomasQ28267366
MicroRNAs of the mammalian eye display distinct and overlapping tissue specificityQ28273936
Effect of gene therapy on visual function in Leber's congenital amaurosisQ28277981
Posttranscriptional regulation of microRNA biogenesis in animalsQ28282519
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblastsQ28511032
Expression and cellular localization of microRNA-29b and RAX, an activator of the RNA-dependent protein kinase (PKR), in the retina of streptozotocin-induced diabetic ratsQ28577524
miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppressionQ28586443
Regulation of mRNA translation and stability by microRNAsQ29547304
Gene silencing by microRNAs: contributions of translational repression and mRNA decayQ29615825
The mirtron pathway generates microRNA-class regulatory RNAs in DrosophilaQ29615827
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infectionQ29615959
Efficient non-viral ocular gene transfer with compacted DNA nanoparticlesQ33267297
MicroRNA profile of the developing mouse retina.Q33516456
Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasmQ33553406
MicroRNA-183 family members regulate sensorineural fates in the inner ear.Q33766505
What can we learn about age-related macular degeneration from other retinal diseases?Q33774176
miRNeye: a microRNA expression atlas of the mouse eye.Q33776125
Dicer is required for the transition from early to late progenitor state in the developing mouse retinaQ33786364
Emerging paradigms of regulated microRNA processingQ33885669
A resource of vectors and ES cells for targeted deletion of microRNAs in mice.Q33984727
MicroRNA biogenesis via splicing and exosome-mediated trimming in DrosophilaQ33995936
miR-204 is required for lens and retinal development via Meis2 targetingQ34100520
Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3'UTRsQ34115739
MicroRNAs can generate thresholds in target gene expressionQ34209703
Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430.Q34673364
MicroRNA-200b regulates vascular endothelial growth factor-mediated alterations in diabetic retinopathyQ34718910
Kaposi's sarcoma-associated herpesvirus ORF57 promotes escape of viral and human interleukin-6 from microRNA-mediated suppressionQ34742851
DICER1 deficit induces Alu RNA toxicity in age-related macular degenerationQ34796058
Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs.Q34803039
Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans developmentQ34927780
microRNA-24a is required to repress apoptosis in the developing neural retinaQ34976201
Epigenetics and genetics. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapyQ35039281
Gene therapy for ocular diseasesQ35160142
Sponge transgenic mouse model reveals important roles for the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors of the retinaQ35213123
Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutantsQ35222458
miR-146a-Mediated extracellular matrix protein production in chronic diabetes complications.Q35404898
microRNA-34c is a novel target to treat dementiasQ35422390
Focus on vision: 3 decades of remarkable contributions to biology and medicineQ35585403
MicroRNA-204/211 alters epithelial physiologyQ35595622
The biogenesis and characterization of mammalian microRNAs of mirtron origin.Q35633635
P433issue16
P921main subjectmicroRNAQ310899
P304page(s)2739-2750
P577publication date2012-03-30
P1433published inCellular and Molecular Life SciencesQ5058352
P1476titleThe physiological impact of microRNA gene regulation in the retina
P478volume69

Reverse relations

cites work (P2860)
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