Erlotinib added to carboplatin and paclitaxel as first-line treatment of ovarian cancer: a phase II study based on surgical reassessment.

scientific article

Erlotinib added to carboplatin and paclitaxel as first-line treatment of ovarian cancer: a phase II study based on surgical reassessment. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YGYNO.2010.08.008
P932PMC publication ID3446254
P698PubMed publication ID20837357
P5875ResearchGate publication ID46255324

P50authorJohn P. CurtinQ38801361
Franco MuggiaQ30512486
P2093author name stringLeonard Liebes
Paul Christos
Joseph A Sparano
Helen X Chen
Stephanie V Blank
Carolyn D Runowicz
Noah Goldman
P2860cites workTargeted inhibition of transient activation of the EGFR-mediated cell survival pathway enhances paclitaxel-induced ovarian cancer cell death.Q38320166
Improved survival for fallopian tube cancer: a comparison of clinical characteristics and outcome for primary fallopian tube and ovarian cancer.Q40028239
Improved survival time: what can survival cure models tell us about population-based survival improvements in late-stage colorectal, ovarian, and testicular cancer?Q40105863
Enhanced sensitivity to the HER1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib hydrochloride in chemotherapy-resistant tumor cell lines.Q40451017
Determinants of tumor response and survival with erlotinib in patients with non--small-cell lung cancerQ40489484
Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancerQ40673230
Final survival and safety results from a multicenter, open-label, phase 3b trial of erlotinib in patients with advanced nonsmall cell lung cancerQ42653421
Phase II study of gefitinib in patients with relapsed or persistent ovarian or primary peritoneal carcinoma and evaluation of epidermal growth factor receptor mutations and immunohistochemical expression: a Gynecologic Oncology Group StudyQ46630310
Efficacy and safety of erlotinib HCl, an epidermal growth factor receptor (HER1/EGFR) tyrosine kinase inhibitor, in patients with advanced ovarian carcinoma: results from a phase II multicenter studyQ46712990
Effect of Epidermal Growth Factor Receptor Expression Level on Survival in Patients with Epithelial Ovarian CancerQ57904896
Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: the Tarceva Lung Cancer Investigation TrialQ80178480
Epithelial growth factor receptor status in primary and recurrent ovarian cancerQ82917858
Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinomaQ83139511
Global cancer statistics, 2002Q27860562
Erlotinib in previously treated non-small-cell lung cancerQ29547546
Cancer statistics, 2009Q29547625
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Evaluation of new platinum-based treatment regimens in advanced-stage ovarian cancer: a Phase III Trial of the Gynecologic Cancer IntergroupQ30436714
Gefitinib: a review of its use in the management of advanced non-small-cell lung cancerQ33207883
Comparison of RNA amplification methods and chip platforms for microarray analysis of samples processed by laser capture microdissectionQ33286603
Phase III randomized study of cisplatin versus paclitaxel versus cisplatin and paclitaxel in patients with suboptimal stage III or IV ovarian cancer: a gynecologic oncology group studyQ33331105
Review of the comparative pharmacology and clinical activity of cisplatin and carboplatinQ33718099
TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer.Q34436986
Cutaneous adverse effects with HER1/EGFR-targeted agents: is there a silver lining?Q36211421
A review of erlotinib and its clinical use.Q36376408
Panitumumab: in the treatment of metastatic colorectal cancerQ36651665
Role of surgery in ovarian carcinomaQ36873048
Cetuximab: a review of its use in squamous cell carcinoma of the head and neck and metastatic colorectal cancerQ37011976
Phase II trial of single agent cetuximab in patients with persistent or recurrent epithelial ovarian or primary peritoneal carcinoma with the potential for dose escalation to rashQ37340624
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
carboplatinQ415588
erlotinibQ418369
paclitaxelQ423762
P304page(s)451-456
P577publication date2010-09-15
P1433published inGynecologic OncologyQ5625182
P1476titleErlotinib added to carboplatin and paclitaxel as first-line treatment of ovarian cancer: a phase II study based on surgical reassessment
P478volume119

Reverse relations

cites work (P2860)
Q33835932A loop of cancer-stroma-cancer interaction promotes peritoneal metastasis of ovarian cancer via TNFα-TGFα-EGFR
Q83389063A phase II trial of Erlotinib in combination with gemcitabine and cisplatin in advanced pancreatic cancer
Q38631373An overview of tyrosine kinase inhibitors for the treatment of epithelial ovarian cancer.
Q36321894Anti-epidermal growth factor receptor (EGFR) antibodies overcome resistance of ovarian cancer cells to targeted therapy and natural cytotoxicity
Q38965047BRCA1-IRIS inactivation sensitizes ovarian tumors to cisplatin
Q37637147Characterization of ovarian clear cell carcinoma using target drug-based molecular biomarkers: implications for personalized cancer therapy
Q37671783Comprehensive profiling of EGFR/HER receptors for personalized treatment of gynecologic cancers
Q35767493Contributions of the Epidermal Growth Factor Receptor to Acquisition of Platinum Resistance in Ovarian Cancer Cells
Q33829859Dacomitinib, a pan-inhibitor of ErbB receptors, suppresses growth and invasive capacity of chemoresistant ovarian carcinoma cells
Q90224747EGFR-Specific Tyrosine Kinase Inhibitor Modifies NK Cell-Mediated Antitumoral Activity against Ovarian Cancer Cells
Q26863231EGFR/HER-targeted therapeutics in ovarian cancer
Q36322658Epidermal Growth Factor Receptor (EGFR) Pathway Biomarkers in the Randomized Phase III Trial of Erlotinib Versus Observation in Ovarian Cancer Patients with No Evidence of Disease Progression after First-Line Platinum-Based Chemotherapy
Q24236143Epidermal growth factor receptor blockers for the treatment of ovarian cancer
Q57456685Epidermal growth factor receptor blockers for the treatment of ovarian cancer
Q91603678Human epidermal growth factor receptor targeted inhibitors for the treatment of ovarian cancer
Q52717288Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma.
Q90231859Kinase Inhibitors and Ovarian Cancer
Q37185385Network analysis identifies an HSP90-central hub susceptible in ovarian cancer
Q47424260Novel antiangiogenic therapies in ovarian cancer
Q35659945Ovarian cancer: opportunity for targeted therapy
Q36880902Profile of erlotinib and its potential in the treatment of advanced ovarian carcinoma
Q55491850Small Molecules Identified from a Quantitative Drug Combinational Screen Resensitize Cisplatin's Response in Drug-Resistant Ovarian Cancer Cells.
Q35619189Synergistic anti-tumor effect of combined inhibition of EGFR and JAK/STAT3 pathways in human ovarian cancer
Q98164379Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence
Q38118388Targeting tyrosine-kinases in ovarian cancer
Q30248645The Emerging Role of Tyrosine Kinase Inhibitors in Ovarian Cancer Treatment: A Systematic Review
Q38144166The potential of sunitinib as a therapy in ovarian cancer
Q50345037The rise of genomic profiling in ovarian cancer
Q34806737The therapeutic potential of targeting the EGFR family in epithelial ovarian cancer
Q38248418Treatment of ovarian cancer beyond chemotherapy: are we hitting the target?

Search more.