Dissecting the genetic determinants of hemostasis and thrombosis

scientific article

Dissecting the genetic determinants of hemostasis and thrombosis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1097/MOH.0000000000000165
P932PMC publication ID4636909
P698PubMed publication ID26248003

P2093author name stringKarl C Desch
P2860cites workIdentifying novel genetic determinants of hemostatic balanceQ36230809
The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levelsQ37043558
A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortiumQ37708719
Influence of hereditary or acquired thrombophilias on the treatment of venous thromboembolismQ38023637
Dysfunction of protein C anticoagulant system, main genetic risk factor for venous thromboembolism in northeast AsiansQ38162754
The role of regulatory variation in complex traits and diseaseQ38364456
Extremely low-coverage sequencing and imputation increases power for genome-wide association studiesQ41882858
A multi-stage multi-design strategy provides strong evidence that the BAI3 locus is associated with early-onset venous thromboembolismQ43894795
Influence of thrombophilia on risk of recurrent venous thromboembolism while on warfarin: results from a randomized trialQ46368145
The genetics of venous thromboembolism. A meta-analysis involving approximately 120,000 cases and 180,000 controlsQ50324464
Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach.Q51773327
Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA projectQ57611749
Genome-wide linkage analysis of von Willebrand factor plasma levels: results from the GAIT projectQ59590827
CLEC4MandSTXBP5gene variations contribute to von Willebrand factor level variation in von Willebrand diseaseQ62107228
High levels of factor VIII and venous thrombosisQ73434262
High plasma concentration of factor VIIIc is a major risk factor for venous thromboembolismQ73434266
Gene variants associated with deep vein thrombosisQ80893876
Combined analysis of three genome-wide association studies on vWF and FVIII plasma levelsQ24318690
Complement factor H polymorphism in age-related macular degenerationQ24553334
Familial thrombophilia due to a previously unrecognized mechanism characterized by poor anticoagulant response to activated protein C: prediction of a cofactor to activated protein CQ24563608
The NHGRI GWAS Catalog, a curated resource of SNP-trait associationsQ24568334
Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.Q28658007
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular diseaseQ28661433
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterolQ30411390
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulationQ30415902
Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.Q30590837
A genome-wide search for common SNP x SNP interactions on the risk of venous thrombosisQ31113588
von Willebrand factor: two sides of a coinQ33367858
Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin timeQ33772986
Synthetic associations created by rare variants do not explain most GWAS resultsQ33803707
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) ConsortiumQ33817075
Genetic susceptibility to thrombosis and its relationship to physiological risk factors: the GAIT study. Genetic Analysis of Idiopathic ThrombophiliaQ34144305
Congenital thrombophilic states associated with venous thrombosis: a qualitative overview and proposed classification systemQ34170635
Linkage analysis identifies a locus for plasma von Willebrand factor undetected by genome-wide associationQ34319603
Mutation in blood coagulation factor V associated with resistance to activated protein C.Q34340007
A common genetic variation in the 3'-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis.Q34407258
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC studyQ34450740
Genetic variants in PLG, LPA, and SIGLEC 14 as well as smoking contribute to plasma plasminogen levelsQ34508365
Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosisQ35037432
Genetic markers associated with plasma protein C level in African Americans: the atherosclerosis risk in communities (ARIC) studyQ35162846
Factor VIII and factor IX in a twin population. Evidence for a major effect of ABO locus on factor VIII levelQ35200124
Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolismQ35266365
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathwaysQ35624305
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery diseaseQ36096131
A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q.Q36166323
P433issue5
P921main subjectthrombosisQ261327
P304page(s)428-436
P577publication date2015-09-01
P1433published inCurrent Opinion in HematologyQ15757961
P1476titleDissecting the genetic determinants of hemostasis and thrombosis
P478volume22

Search more.