Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity

scientific article

Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.0826-15.2015
P932PMC publication ID4642238
P698PubMed publication ID26558777

P50authorSamuel K PowellQ86677613
P2093author name stringClaes Wahlestedt
Shaun P Brothers
Gregory C Sartor
P2860cites workStructure and ligand of a histone acetyltransferase bromodomainQ22009928
Selective inhibition of BET bromodomainsQ24301009
Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cellsQ24301441
An epigenetic mouse model for molecular and behavioral neuropathologies related to schizophrenia vulnerabilityQ24544035
The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5pQ24596953
Small-molecule inhibition of BRDT for male contraceptionQ24616901
Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuinsQ24654085
Cooperative binding of two acetylation marks on a histone tail by a single bromodomainQ27657619
Suppression of inflammation by a synthetic histone mimicQ27665789
Discovery and characterization of small molecule inhibitors of the BET family bromodomainsQ27667834
The bromodomain: a chromatin-targeting module?Q28139513
Targeting bromodomains: epigenetic readers of lysine acetylationQ28238635
BET bromodomain inhibition as a therapeutic strategy to target c-MycQ28247024
BET domain co-regulators in obesity, inflammation and cancerQ28269301
Aberrant histone deacetylase2-mediated histone modifications and synaptic plasticity in the amygdala predisposes to anxiety and alcoholismQ28574090
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuliQ28591800
MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212.Q28909710
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemiaQ29617201
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosisQ29618035
Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatumQ29620475
HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity.Q30457800
Modulation of chromatin modification facilitates extinction of cocaine-induced conditioned place preferenceQ30492380
Epigenetic inheritance of a cocaine-resistance phenotypeQ30530759
Class I HDAC inhibition blocks cocaine-induced plasticity by targeted changes in histone methylationQ30538086
Clinical Toxicities of Histone Deacetylase InhibitorsQ31135325
CRACKing the histone code: cocaine's effects on chromatin structure and functionQ33349374
Essential role of the histone methyltransferase G9a in cocaine-induced plasticityQ33646214
Acute cocaine increases interleukin-1β mRNA and immunoreactive cells in the cortex and nucleus accumbens.Q33668515
Endogenous BDNF in the dorsolateral striatum gates alcohol drinkingQ33793424
BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.Q33936571
CBP in the nucleus accumbens regulates cocaine-induced histone acetylation and is critical for cocaine-associated behaviorsQ34029497
Cocaine-induced chromatin remodeling increases brain-derived neurotrophic factor transcription in the rat medial prefrontal cortex, which alters the reinforcing efficacy of cocaineQ34145195
Increasing histone acetylation in the hippocampus-infralimbic network enhances fear extinctionQ34250699
HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent mannerQ34321375
Chronic cocaine-induced H3 acetylation and transcriptional activation of CaMKIIalpha in the nucleus accumbens is critical for motivation for drug reinforcement.Q34660656
Increased brain-derived neurotrophic factor (BDNF) expression in the ventral tegmental area during cocaine abstinence is associated with increased histone acetylation at BDNF exon I-containing promotersQ35626919
Bromodomain inhibitors regulate the C9ORF72 locus in ALSQ35670978
The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferationQ35846001
A septal-hypothalamic pathway drives orexin neurons, which is necessary for conditioned cocaine preferenceQ35954496
Elevations of FosB in the nucleus accumbens during forced cocaine abstinence correlate with divergent changes in reward functionQ36003138
Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins.Q36377977
BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in miceQ36575895
FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effectsQ36586953
BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses.Q36718203
HDAC3 is a negative regulator of cocaine-context-associated memory formationQ36896817
BRD4 coordinates recruitment of pause release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon-stimulated genesQ36978246
FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages.Q37400789
Place your BETs: the therapeutic potential of bromodomainsQ37978695
Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in ratsQ39972608
The roles of glial cell line-derived neurotrophic factor, tumor necrosis factor-alpha, and an inducer of these factors in drug dependenceQ40126015
NF-κB directs dynamic super enhancer formation in inflammation and atherogenesisQ41971115
Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine rewardQ42122779
Implication of brain-derived neurotrophic factor in the release of dopamine and dopamine-related behaviors induced by methamphetamineQ42443075
I-BET151 selectively regulates IL-6 productionQ42776418
Amphetamine-induced locomotion and gene expression are altered in BDNF heterozygous miceQ43225815
Time-dependent increases in brain-derived neurotrophic factor protein levels within the mesolimbic dopamine system after withdrawal from cocaine: implications for incubation of cocaine craving.Q44306921
A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal.Q44770115
Ethanol-responsive brain region expression networks: implications for behavioral responses to acute ethanol in DBA/2J versus C57BL/6J mice.Q44908892
Identification of unique, differentiation stage-specific patterns of expression of the bromodomain-containing genes Brd2, Brd3, Brd4, and Brdt in the mouse testisQ44984862
A single cocaine exposure increases BDNF and D3 receptor expression: implications for drug-conditioning.Q45239066
Repeated stress prevents cocaine-induced activation of BDNF signaling in rat prefrontal cortexQ46119250
The effects of sodium butyrate, an inhibitor of histone deacetylase, on the cocaine- and sucrose-maintained self-administration in ratsQ46503506
Nicotine-induced sensitization in mice: changes in locomotor activity and mesencephalic gene expressionQ46782485
Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaineQ46866917
Alterations in BDNF and trkB mRNAs following acute or sensitizing cocaine treatments and withdrawalQ46901427
Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapseQ48112100
Brain-derived neurotrophic factor and neurotrophin-3 activate striatal dopamine and serotonin metabolism and related behaviors: interactions with amphetamineQ48165295
Enhancement of locomotor activity and conditioned reward to cocaine by brain-derived neurotrophic factor.Q48218197
Dynamic changes of brain-derived neurotrophic factor protein levels in the rat forebrain after single and recurring kindling-induced seizuresQ48538187
Anterograde transport of brain-derived neurotrophic factor and its role in the brainQ48539947
P4510describes a project that usesImageJQ1659584
P433issue45
P407language of work or nameEnglishQ1860
P304page(s)15062-15072
P577publication date2015-11-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleEpigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity
P478volume35

Reverse relations

cites work (P2860)
Q99569291BET bromodomains as novel epigenetic targets for brain health and disease
Q40648892BRG1 in the Nucleus Accumbens Regulates Cocaine-Seeking Behavior
Q38906390Bromodomain 4: a cellular Swiss army knife
Q91692887Chromatin Regulation in Complex Brain Disorders
Q51747326Cocaine Exposure Increases Blood Pressure and Aortic Stiffness via the miR-30c-5p-Malic Enzyme 1-Reactive Oxygen Species Pathway.
Q50437568Drug Addiction and Histone Code Alterations.
Q30352390Drug Discovery Targeting Bromodomain-Containing Protein 4.
Q50592833Dysregulation of BET proteins in levodopa-induced dyskinesia.
Q50020887Emerging Epigenetic Therapies in Neuroscience: Focus on Bromodomain-Containing Drug Targets
Q90028863Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins
Q37714196Epigenetic intervention with a BET inhibitor ameliorates acute retinal ganglion cell death in mice
Q37130046Glycosylation and other PTMs alterations in neurodegenerative diseases: Current status and future role in neurotrauma
Q91272551How the epigenome integrates information and reshapes the synapse
Q58612166Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model
Q46956989M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory
Q36521971Nociceptin receptor activation does not alter acquisition, expression, extinction and reinstatement of conditioned cocaine preference in mice
Q37595667Photoreceptor protection via blockade of BET epigenetic readers in a murine model of inherited retinal degeneration
Q40241152Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine
Q39173763Striatal H3K27 Acetylation Linked to Glutamatergic Gene Dysregulation in Human Heroin Abusers Holds Promise as Therapeutic Target.
Q37261981The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease
Q42257140The BET/BRD inhibitor JQ1 improves brain plasticity in WT and APP mice.
Q99591044The Emerging Role of ATP-Dependent Chromatin Remodeling in Memory and Substance Use Disorders

Search more.