Importance of the Voltage Dependence of Cardiac Na/K ATPase Isozymes

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Importance of the Voltage Dependence of Cardiac Na/K ATPase Isozymes is …
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scholarly articleQ13442814

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P356DOI10.1016/J.BPJ.2015.09.015
P932PMC publication ID4643266
P698PubMed publication ID26536262

P2093author name stringPablo Artigas
Dominique G Gagnon
Adam Bernal
Christopher M Stanley
Dylan J Meyer
Joshua J Rosenthal
P2860cites workTransport and pharmacological properties of nine different human Na, K-ATPase isozymesQ22011056
Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomainQ24295272
The influence of calcium on sodium efflux in squid axonsQ24538970
Regional expression of sodium pump subunits isoforms and Na+-Ca++ exchanger in the human heartQ24561959
The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heartQ28512885
The Na,K-ATPase alpha 2 isoform is expressed in neurons, and its absence disrupts neuronal activity in newborn miceQ28589473
Role of phospholemman phosphorylation sites in mediating kinase-dependent regulation of the Na+-K+-ATPaseQ30429397
Extracellular potassium dependence of the Na+-K+-ATPase in cardiac myocytes: isoform specificity and effect of phospholemman.Q30434871
Functional differences between alpha subunit isoforms of the rat Na,K-ATPase expressed in Xenopus oocytesQ33183494
Sodium and proton effects on inward proton transport through Na/K pumpsQ33803674
Selectivity of digitalis glycosides for isoforms of human Na,K-ATPaseQ33911448
A third Na+-binding site in the sodium pumpQ33943950
Distribution of Na/K-ATPase alpha 3 isoform, a sodium-potassium P-type pump associated with rapid-onset of dystonia parkinsonism (RDP) in the adult mouse brainQ42481415
Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.Q42604432
Ouabain binding kinetics of the rat alpha two and alpha three isoforms of the sodium-potassium adenosine triphosphateQ42800002
Differential centrifugation separates cardiac sarcolemmal and endosomal membranes from Langendorff-perfused rat heartsQ43634643
Electrophysiologic properties of intercostal muscle fibers in human neuromuscular diseasesQ43869949
Postnatal changes in Na,K-ATPase isoform expression in rat cardiac ventricle. Conservation of biphasic ouabain affinityQ44284534
Regulation of Ca2+ signaling by Na+ pump alpha-2 subunit expressionQ44451844
Skeletal muscle Na,K-ATPase alpha and beta subunit protein levels respond to hypokalemic challenge with isoform and muscle type specificityQ44565630
Comparison of the substrate dependence properties of the rat Na,K-ATPase alpha 1, alpha 2, and alpha 3 isoforms expressed in HeLa cellsQ44813848
Phylogenetic conservation of isoform-specific regions within alpha-subunit of Na(+)-K(+)-ATPaseQ45331243
Structure-function relationships in the Na,K-ATPase alpha subunit: site-directed mutagenesis of glutamine-111 to arginine and asparagine-122 to aspartic acid generates a ouabain-resistant enzymeQ45790576
Subcellular distribution of sodium pump isoform subunits in mammalian cardiac myocytes.Q45945297
2,3-butanedione monoxime affects cystic fibrosis transmembrane conductance regulator channel function through phosphorylation-dependent and phosphorylation-independent mechanisms: the role of bilayer material propertiesQ46174841
Immunologic identification of Na+,K(+)-ATPase isoforms in myocardium. Isoform change in deoxycorticosterone acetate-salt hypertensionQ46243995
Phospholemman-phosphorylation mediates the beta-adrenergic effects on Na/K pump function in cardiac myocytesQ46588903
Phosphorylation of phospholemman (FXYD1) by protein kinases A and C modulates distinct Na,K-ATPase isozymesQ48773026
Electrophysiological Analysis of the Mutated Na,K-ATPase Cation Binding PocketQ48820652
Isozymes of the Na-K-ATPase: heterogeneity in structure, diversity in function.Q52182292
Na-K-ATPase alpha-isoform expression in heart and vascular endothelia: cellular and developmental regulation.Q52203750
Tissue-specific and developmental regulation of rat Na,K-ATPase catalytic alpha isoform and beta subunit mRNAs.Q52250938
Electrogenic K+ transport by the Na(+)-K+ pump in rat cardiac ventricular myocytes.Q53000023
Differential distribution and regulation of mouse cardiac Na+/K+-ATPase alpha1 and alpha2 subunits in T-tubule and surface sarcolemmal membranes.Q54361992
STOICHIOMETRY AND LOCALIZATION OF ADENOSINE TRIPHOSPHATE-DEPENDENT SODIUM AND POTASSIUM TRANSPORT IN THE ERYTHROCYTEQ76707076
Subunit composition and role of Na+,K+-ATPases in ventricular myocytesQ79739391
Functional analysis of Na+/K+-ATPase isoform distribution in rat ventricular myocytesQ80057919
An N-terminal sequence targets and tethers Na+ pump alpha2 subunits to specialized plasma membrane microdomainsQ82766016
The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ionsQ33950710
Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport propertiesQ34038902
Selectivity of externally facing ion-binding sites in the Na/K pump to alkali metals and organic cationsQ34276883
Immunostaining for the α3 isoform of the Na+/K+-ATPase is selective for functionally identified muscle spindle afferents in vivo.Q34408704
The functional role of beta subunits in oligomeric P-type ATPasesQ34474661
FXYD proteins reverse inhibition of the Na+-K+ pump mediated by glutathionylation of its beta1 subunitQ34998062
Contributions of the Na⁺/K⁺-ATPase, NKCC1, and Kir4.1 to hippocampal K⁺ clearance and volume responsesQ34998931
Physiological adaptation of an Antarctic Na+/K+-ATPase to the coldQ35032313
Energy landscape of the reactions governing the Na+ deeply occluded state of the Na+/K+-ATPase in the giant axon of the Humboldt squidQ35651403
beta-Adrenergic modulation of the inwardly rectifying potassium channel in isolated human ventricular myocytes. Alteration in channel response to beta-adrenergic stimulation in failing human heartsQ35768797
Na+ pump low and high ouabain affinity alpha subunit isoforms are differently distributed in cellsQ36022585
Na,K-ATPase α2 activity in mammalian skeletal muscle T-tubules is acutely stimulated by extracellular K+.Q36102228
Subunit isoform selectivity in assembly of Na,K-ATPase α-β heterodimersQ36122189
The NA/K-ATPase and its isozymes: what we have learned using the baculovirus expression systemQ36170251
Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytesQ36173019
Na,K-ATPase subunit heterogeneity as a mechanism for tissue-specific ion regulationQ36247877
Excitation-contraction coupling in cardiac Purkinje fibers. Effects of cardiotonic steroids on the intracellular [Ca2+] transient, membrane potential, and contractionQ36408937
Modulation of the Na,K-pump function by beta subunit isoformsQ36411532
Quaternary organic amines inhibit Na,K pump current in a voltage-dependent manner: direct evidence of an extracellular access channel in the Na,K-ATPaseQ36412531
Molecular cloning of three distinct forms of the Na+,K+-ATPase alpha-subunit from rat brainQ36426324
Block of squid axon K channels by internally and externally applied barium ionsQ36433160
Steady-state current-voltage relationship of the Na/K pump in guinea pig ventricular myocytesQ36434402
[Na] and [K] dependence of the Na/K pump current-voltage relationship in guinea pig ventricular myocytesQ36434429
Two functionally different Na/K pumps in cardiac ventricular myocytesQ36435565
Tissue-specific role of the Na,K-ATPase α2 isozyme in skeletal muscleQ36526296
How membrane proteins sense voltageQ37114573
FXYD1 phosphorylation in vitro and in adult rat cardiac myocytes: threonine 69 is a novel substrate for protein kinase C.Q37216812
Altered Na+ transport after an intracellular alpha-subunit deletion reveals strict external sequential release of Na+ from the Na/K pumpQ37340893
Isoform specificity of the Na/K-ATPase association and regulation by phospholemmanQ37446797
Voltage dependence of the Na-K pumpQ39644432
Diverse functional consequences of mutations in the Na+/K+-ATPase alpha2-subunit causing familial hemiplegic migraine type 2Q39947054
Hypokalaemia induces Ca(2+) overload and Ca(2+) waves in ventricular myocytes by reducing Na(+),K(+)-ATPase α2 activityQ41220726
Kinetic properties of the alpha 2 beta 1 and alpha 2 beta 2 isozymes of the Na,K-ATPaseQ41381335
Na+,K(+)-ATPase pump currents in giant excised patches activated by an ATP concentration jumpQ42124870
Amiodarone decreases Na,K-ATPase alpha 2 and beta 2 expression specifically in cardiac ventricleQ42284071
P4510describes a project that usesImageQuantQ112270642
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)1852-1862
P577publication date2015-11-01
P1433published inBiophysical JournalQ2032955
P1476titleImportance of the Voltage Dependence of Cardiac Na/K ATPase Isozymes
P478volume109

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cites work (P2860)
Q59809830A novel ATP1A2 mutation in a patient with hypokalaemic periodic paralysis and CNS symptoms
Q26738318ATP1A2 Mutations in Migraine: Seeing through the Facets of an Ion Pump onto the Neurobiology of Disease
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Q59125620Hypokalemia-Induced Arrhythmias and Heart Failure: New Insights and Implications for Therapy
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Q43882322Subcellular localization of Na/K-ATPase isoforms in ventricular myocytes
Q33766129The Structure and Function of the Na,K-ATPase Isoforms in Health and Disease

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