Benefits and unintended consequences of antimicrobial de-escalation: Implications for stewardship programs

scientific article

Benefits and unintended consequences of antimicrobial de-escalation: Implications for stewardship programs is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2017PLoSO..1271218H
P356DOI10.1371/JOURNAL.PONE.0171218
P932PMC publication ID5300270
P698PubMed publication ID28182774

P50authorBryan CoburnQ58144514
Josie HughesQ58876486
Lindsey FalkQ89242385
P2093author name stringJianhong Wu
Amy Hurford
Andrew Morris
Kunquan Lan
Xi Huo
P2860cites workGuidelines for the Management of Adults with Hospital-acquired, Ventilator-associated, and Healthcare-associated PneumoniaQ22241905
De-escalation of antimicrobial treatment for adults with sepsis, severe sepsis or septic shockQ24198268
Pseudomonas aeruginosa: all roads lead to resistanceQ28240246
Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysisQ28303703
Responses of Pseudomonas aeruginosa to antimicrobialsQ28305587
"One-size-fits-all"? Optimizing treatment duration for bacterial infectionsQ28478851
Antibiotic Restriction Might Facilitate the Emergence of Multi-drug ResistanceQ28545750
Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic ResistanceQ28547894
Attributable mortality of ventilator-associated pneumonia: a meta-analysis of individual patient data from randomised prevention studiesQ30620223
Statistical epidemic modeling with hospital outbreak dataQ33365120
Antibiotic control of antibiotic resistance in hospitals: a simulation studyQ33672358
Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: 2009 Update by the Infectious Diseases Society of AmericaQ33688646
Multilevel competing risk models to evaluate the risk of nosocomial infectionQ33750199
Cycling empirical antibiotic therapy in hospitals: meta-analysis and modelsQ33812804
Selection of cross-resistance following exposure of Pseudomonas aeruginosa clinical isolates to ciprofloxacin or cefepimeQ33836617
Informed switching strongly decreases the prevalence of antibiotic resistance in hospital wardsQ33842121
Strategic interactions in multi-institutional epidemics of antibiotic resistanceQ33864106
Assessment of empirical antibiotic therapy optimisation in six hospitals: an observational cohort study.Q33925668
Global sensitivity analysis for complex ecological models: a case study of riparian cottonwood population dynamics.Q33966368
Emergence of fluoroquinolones as the predominant risk factor for Clostridium difficile-associated diarrhea: a cohort study during an epidemic in QuebecQ33990521
The magnitude and duration of Clostridium difficile infection risk associated with antibiotic therapy: a hospital cohort studyQ34089890
Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardshipQ34591740
Modelling the transmission of healthcare associated infections: a systematic reviewQ34786520
Pseudomonas aeruginosa: resistance to the maxQ35084559
Pseudomonas aeruginosa acquisition on an intensive care unit: relationship between antibiotic selective pressure and patients' environmentQ35566984
Pseudomonas aeruginosa carriage, colonization, and infection in ICU patients.Q51004000
The path of least resistance: aggressive or moderate treatment?Q51033406
Hospital-acquired infections--appropriate statistical treatment is urgently needed!Q51163990
Clinical characteristics and treatment patterns among patients with ventilator-associated pneumonia.Q51206353
A network-based approach for resistance transmission in bacterial populations.Q51793791
Clinical outcomes of health-care-associated infections and antimicrobial resistance in patients admitted to European intensive-care units: a cohort study.Q54374662
Epidemiology of Pseudomonas aeruginosa and risk factors for carriage acquisition in an intensive care unitQ73179918
[Are the prolonged carrier and interhospital clonal diffusion of serotype O12 multiresistant Pseudomonas aeruginosa connected?]Q77116046
The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. The Canadian Critical Trials GroupQ77293121
De-escalation therapy rates are significantly higher by bronchoalveolar lavage than by tracheal aspirateQ80430065
Acquisition of Pseudomonas aeruginosa and its resistance phenotypes in critically ill medical patients: role of colonization pressure and antibiotic exposureQ35608657
Determinants of the Final Size and Case Rate of Nosocomial OutbreaksQ35775814
Epidemiological interpretation of antibiotic resistance studies - what are we missing?Q35954276
Desirability of Outcome Ranking (DOOR) and Response Adjusted for Duration of Antibiotic Risk (RADAR).Q35975462
Early use of imipenem/cilastatin and vancomycin followed by de-escalation versus conventional antimicrobials without de-escalation for patients with hospital-acquired pneumonia in a medical ICU: a randomized clinical trialQ36093598
Multidrug therapy and evolution of antibiotic resistance: when order mattersQ36156421
Analysis and presentation of cumulative antibiograms: a new consensus guideline from the Clinical and Laboratory Standards InstituteQ36737222
Antimicrobial-associated risk factors for Clostridium difficile infectionQ37051298
A modeling framework for the evolution and spread of antibiotic resistance: literature review and model categorizationQ37078552
Impact of superinfection on hospital length of stay and costs in patients with ventilator-associated pneumoniaQ37387157
How to measure the impacts of antibiotic resistance and antibiotic development on empiric therapy: new composite indicesQ37517286
The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts.Q37755968
Contribution of mathematical modeling to the fight against bacterial antibiotic resistanceQ37862035
Antimicrobial de-escalation strategies in hospitalized patients with pneumonia, intra-abdominal infections, and bacteremiaQ38107143
Antibiotic de-escalation in bacteremic urinary tract infections: potential opportunities and effect on outcomeQ38215853
Stress responses as determinants of antimicrobial resistance in Pseudomonas aeruginosa: multidrug efflux and moreQ38267242
Antibiotic de-escalation in the ICU: how is it best done?Q38359950
A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care UnitQ38679343
Linking antimicrobial prescribing to antimicrobial resistance in the ICU: before and after an antimicrobial stewardship programQ39478816
Development of quinolone-imipenem cross resistance in Pseudomonas aeruginosa during exposure to ciprofloxacinQ39817132
Modelling the epidemiology of Escherichia coli ST131 and the impact of interventions on the community and healthcare centresQ40807834
Increased expression of ampC in Pseudomonas aeruginosa mutants selected with ciprofloxacinQ42131963
Clinical outcomes of Pseudomonas aeruginosa pneumonia in intensive care unit patientsQ42276769
Antimicrobial Stewardship Programs: Appropriate Measures and Metrics to Study their ImpactQ42554730
Antimicrobial de-escalation in septic cancer patients: is it safe to back down?Q43240867
De-escalation versus continuation of empirical antimicrobial treatment in severe sepsis: a multicenter non-blinded randomized noninferiority trialQ44019769
De-escalation as a potential way of reducing antibiotic use and antimicrobial resistance in ICU.Q44194515
De-escalation of antimicrobial therapy for bacteraemia due to difficult-to-treat Gram-negative bacilliQ44449024
Diversity of β-lactam resistance mechanisms in cystic fibrosis isolates of Pseudomonas aeruginosa: a French multicentre study.Q44477142
Complexity of resistance mechanisms to imipenem in intensive care unit strains of Pseudomonas aeruginosa.Q45550772
Risk factors for Pseudomonas aeruginosa acquisition in intensive care units: a prospective multicentre studyQ45847929
De-escalation of antimicrobial treatment in neutropenic patients with severe sepsis: results from an observational study.Q46744719
Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients: a retrospective observational studyQ49061695
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)e0171218
P577publication date2017-02-09
P1433published inPLOS OneQ564954
P1476titleBenefits and unintended consequences of antimicrobial de-escalation: Implications for stewardship programs
P478volume12

Reverse relations

cites work (P2860)
Q50095636Effects of Clinically Meaningful Concentrations of Antipseudomonal β-Lactams on Time to Detection and Organism Growth in Blood Culture Bottles
Q61444360Positively interacting strains that co-circulate within a network structured population induce cycling epidemics of Mycoplasma pneumoniae
Q93270300The Relative Impact of Community and Hospital Antibiotic Use on the Selection of Extended-spectrum Beta-lactamase-producing Escherichia coli

Search more.