Enhancer of polycomb coordinates multiple signaling pathways to promote both cyst and germline stem cell differentiation in the Drosophila adult testis

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Enhancer of polycomb coordinates multiple signaling pathways to promote both cyst and germline stem cell differentiation in the Drosophila adult testis is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1006571
P932PMC publication ID5308785
P698PubMed publication ID28196077

P2093author name stringXin Chen
Lijuan Feng
Zhen Shi
P2860cites workHair follicle stem cells provide a functional niche for melanocyte stem cellsQ42483534
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Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testisQ43602218
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Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells.Q52114950
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Novel functions of nanos in downregulating mitosis and transcription during the development of the Drosophila germline.Q52173308
zfh-1 is required for germ cell migration and gonadal mesoderm development in Drosophila.Q52189387
MAP kinase in situ activation atlas during Drosophila embryogenesis.Q52192419
Yan functions as a general inhibitor of differentiation and is negatively regulated by activation of the Ras1/MAPK pathway.Q52207709
Specificity of bone morphogenetic protein-related factors: cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A.Q52216264
bag-of-marbles and benign gonial cell neoplasm act in the germline to restrict proliferation during Drosophila spermatogenesis.Q52559441
punt and schnurri regulate a somatically derived signal that restricts proliferation of committed progenitors in the germline.Q52559443
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A non-cell autonomous role of E(z) to prevent germ cells from turning on a somatic cell markerQ33692440
Microarray analysis uncovers a role for Tip60 in nervous system function and general metabolismQ33873385
Monovalent and unpoised status of most genes in undifferentiated cell-enriched Drosophila testisQ33909578
Somatic support cells restrict germline stem cell self-renewal and promote differentiation.Q33922721
The roles of the Drosophila JAK/STAT pathwayQ33941399
Homoeosis in Drosophila: a new enhancer of polycomb and related homoeotic mutationsQ33949589
Competitiveness for the niche and mutual dependence of the germline and somatic stem cells in the Drosophila testis are regulated by the JAK/STAT signaling.Q33950748
Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogasterQ33956903
Epigenetic regulation of stem cell maintenance in the Drosophila testis via the nucleosome-remodeling factor NURFQ33962563
H2A.Z-containing nucleosomes mediate the thermosensory response in Arabidopsis.Q34020881
Dynamic regulation of alternative splicing and chromatin structure in Drosophila gonads revealed by RNA-seqQ34057709
GAL4 system in Drosophila: a fly geneticist's Swiss army knifeQ34151737
Steroid signaling promotes stem cell maintenance in the Drosophila testisQ34194313
Coordinate regulation of stem cell competition by Slit-Robo and JAK-STAT signaling in the Drosophila testisQ34464595
Somatic control of germline sexual development is mediated by the JAK/STAT pathwayQ34498977
Enhancer of Polycomb is a suppressor of position-effect variegation in Drosophila melanogaster.Q34602120
Telomeric associated sequences of Drosophila recruit polycomb-group proteins in vivo and can induce pairing-sensitive repressionQ34617502
A temporal signature of epidermal growth factor signaling regulates the differentiation of germline cells in testes of Drosophila melanogasterQ34935709
Sequential changes at differentiation gene promoters as they become active in a stem cell lineageQ35001684
Primordial germ-cell development: the zebrafish perspectiveQ35209968
Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes.Q35534379
Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila.Q35570567
Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1Q35748670
Epigenetic regulation of germ cells-remember or forget?Q35751978
Somatic cell encystment promotes abscission in germline stem cells following a regulated block in cytokinesisQ35900981
Socs36E Controls Niche Competition by Repressing MAPK Signaling in the Drosophila TestisQ35903040
Apontic regulates somatic stem cell numbers in Drosophila testesQ35963326
Histone H4 lysine 20 acetylation is associated with gene repression in human cellsQ35985470
Recent advances in Drosophila male germline stem cell biologyQ36312067
The Drosophila cyst stem cell lineage: Partners behind the scenes?Q36312070
Somatic cell lineage is required for differentiation and not maintenance of germline stem cells in Drosophila testes.Q36389537
MicroRNAs downregulate Bag of marbles to ensure proper terminal differentiation in the Drosophila male germlineQ36444115
In vivo regulation of E2F1 by Polycomb group genes in DrosophilaQ36451325
Integrin-dependent anchoring of a stem-cell nicheQ36487005
Epigenetic regulator Lid maintains germline stem cells through regulating JAK-STAT signaling pathway activityQ36506699
Stem cells, ageing and the quest for immortality.Q36523915
The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testisQ36529610
Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis nicheQ36640835
Male and female Drosophila germline stem cells: two versions of immortality.Q36796598
The nuclear lamina regulates germline stem cell niche organization via modulation of EGFR signalingQ36987569
JAK-STAT pathway in Drosophila morphogenesis: From organ selector to cell behavior regulatorQ37168148
Evidence for tissue-specific Jak/STAT target genes in Drosophila optic lobe developmentQ37320591
Less is more: specification of the germline by transcriptional repressionQ37321822
Epigenetic regulation in adult stem cells and cancersQ37366481
The actin-binding protein profilin is required for germline stem cell maintenance and germ cell enclosure by somatic cyst cellsQ37398477
Jak-STAT regulation of male germline stem cell establishment during Drosophila embryogenesisQ37422683
Drosophila stem cell niches: a decade of discovery suggests a unified view of stem cell regulation.Q37901791
Regulation of proliferation, cell competition, and cellular growth by the Drosophila JAK-STAT pathwayQ38143968
The large Maf factor Traffic Jam controls gonad morphogenesis in DrosophilaQ38348751
Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex.Q39528848
Alteration of enhancer of polycomb 1 at 10p11.2 is one of the genetic events leading to development of adult T-cell leukemia/lymphomaQ39844535
Distribution of acetylated histones resulting from Gal4-VP16 recruitment of SAGA and NuA4 complexesQ39958860
Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cellsQ40024356
Vein expression is induced by the EGF receptor pathway to provide a positive feedback loop in patterning the Drosophila embryonic ventral ectodermQ40442165
Acetylation by Tip60 is required for selective histone variant exchange at DNA lesionsQ40495236
Putative involvement of the histone acetyltransferase Tip60 in ribosomal gene transcriptionQ40579161
SOCS36E, a novel Drosophila SOCS protein, suppresses JAK/STAT and EGF-R signalling in the imaginal wing discQ40720195
MECP2 truncating mutations cause histone H4 hyperacetylation in Rett syndromeQ40808969
Histone H4 isoforms acetylated at specific lysine residues define individual chromosomes and chromatin domains in Drosophila polytene nucleiQ41116253
JAK-STAT signal inhibition regulates competition in the Drosophila testis stem cell nicheQ41907556
bag-of-marbles: a Drosophila gene required to initiate both male and female gametogenesisQ42102438
An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity.Q42151370
Jak-STAT regulation of cyst stem cell development in the Drosophila testisQ42404621
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesedgeRQ113334690
P433issue2
P921main subjectstem cell differentiationQ14864672
cystQ193211
DrosophilaQ312154
P304page(s)e1006571
P577publication date2017-02-14
P1433published inPLOS GeneticsQ1893441
P1476titleEnhancer of polycomb coordinates multiple signaling pathways to promote both cyst and germline stem cell differentiation in the Drosophila adult testis
P478volume13

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