Tubulointerstitial changes as a major determinant in the progression of renal damage

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Tubulointerstitial changes as a major determinant in the progression of renal damage is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0272-6386(12)80312-X
P698PubMed publication ID1621674

P2093author name stringK A Nath
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P433issue1
P304page(s)1-17
P577publication date1992-07-01
P1433published inAmerican Journal of Kidney DiseasesQ4744250
P1476titleTubulointerstitial changes as a major determinant in the progression of renal damage
P478volume20

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Q33579577Perirenal fat thickness measured with computed tomography is a reliable estimate of perirenal fat mass.
Q36677363Peritubular ischemia contributes more to tubular damage than proteinuria in immune-mediated glomerulonephritis
Q88593618Persistent Microscopic Hematuria as a Risk Factor for Progression of IgA Nephropathy: New Floodlight on a Nearly Forgotten Biomarker
Q42522029Pexicrine effects of basement membrane components on paracrine signaling by renal tubular cells
Q43969708Phenotypic changes and cell cycle activation in early tubulointerstitial injury of rat adriamycin nephrosis
Q36753326Phenotypic transitions and fibrosis in diabetic nephropathy
Q35773580Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis.
Q35019442Predicting outcomes of lupus nephritis with tubulointerstitial inflammation and scarring
Q64253047Prediction of Drug Positioning for Quan-Du-Zhong Capsules Against Hypertensive Nephropathy Based on the Robustness of Disease Network
Q36167999Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis
Q72403182Proceedings of the American Society of Pediatric Nephrology 1993 Education Symposium, Washington, D.C., 4 May, 1993
Q57803709Profibrotic effects of angiotensin II and transforming growth factor beta on feline kidney epithelial cells
Q40506590Prognosis in systemic lupus erythematosus
Q39464387Progression of Chronic Kidney Disease After Acute Kidney Injury: Role of Self-Perpetuating Versus Hemodynamic-Induced Fibrosis
Q33787746Progression of chronic renal disease in the dog.
Q41667549Progression of renal damage in human glomerulonephritides: is there sleight of hand in winning the game?
Q44265323Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade
Q38775811Protein DJ-1 and its anti-oxidative stress function play an important role in renal cell mediated response to profibrotic agents.
Q41280800Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo
Q42784841Proteomic analysis of human proximal tubular cells exposed to high glucose concentrations
Q52680882Proximal Tubular Secretory Clearance: A Neglected Partner of Kidney Function.
Q89964386Puerarin Attenuates Diabetic Nephropathy by Promoting Autophagy in Podocytes
Q33691222Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling
Q36104887Rationale and Approaches to Phosphate and Fibroblast Growth Factor 23 Reduction in CKD.
Q39303904Recent Advances in Magnetic Resonance Imaging Assessment of Renal Fibrosis
Q60927232Recent advances in renal imaging
Q33806541Recent advances in the understanding of renal inflammation and fibrosis in lupus nephritis.
Q40003255Recombinant N-Terminal Slit2 Inhibits TGF-β-Induced Fibroblast Activation and Renal Fibrosis
Q33271012Reduction of VEGF-A and CTGF expression in diabetic nephropathy is associated with podocyte loss.
Q73961023Reduction of insulin and triglycerides delays glomerulosclerosis in obese Zucker rats
Q91707078Refining the Mouse Subtotal Nephrectomy in Male 129S2/SV Mice for Consistent Modeling of Progressive Kidney Disease With Renal Inflammation and Cardiac Dysfunction
Q40813544Regulating factors of renal tubular hypertrophy
Q82735153Remodeling of renal interstitial and tubular lesions in pancreas transplant recipients
Q92702775Renal Consequences of Gestational Diabetes Mellitus in Term Neonates: A Multidisciplinary Approach to the DOHaD Perspective in the Prevention and Early Recognition of Neonates of GDM Mothers at Risk of Hypertension and Chronic Renal Diseases in Late
Q41494937Renal Interstitial Fibrosis: An Imperfect Predictor of Kidney Disease Progression in Some Patient Cohorts
Q36698253Renal ageing
Q34457886Renal arterial resistive index is associated with severe histological changes and poor renal outcome during chronic kidney disease
Q27021975Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury
Q50097164Renal fibrosis: Primacy of the proximal tubule.
Q35746896Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation
Q38181476Renal interstitial fibrosis and Angiotensin inhibition
Q38003572Renal interstitial hyaluronan: functional aspects during normal and pathological conditions.
Q82715862Renal protective effects of aliskiren beyond its antihypertensive property in a mouse model of progressive fibrosis
Q64237620Renal shear wave elastography and urinary procollagen type III amino-terminal propeptide (uPIIINP) in feline chronic kidney disease
Q40232940Renal upregulation of HO-1 reduces albumin-driven MCP-1 production: implications for chronic kidney disease
Q40995376Reshaping the interstitium by platelet-derived growth factor. Implications for progressive renal disease.
Q51638670Resistive index predicts renal prognosis in chronic kidney disease: results of a 4-year follow-up.
Q87327833Response of urinary liver-type fatty acid-binding protein to contrast media administration has a potential to predict one-year renal outcome in patients with ischemic heart disease
Q79888640Restricted intake of dietary advanced glycation end products retards renal progression in the remnant kidney model
Q38317847Ring-Sp1 decoy oligonucleotide effectively suppresses extracellular matrix gene expression and fibrosis of rat kidney induced by unilateral ureteral obstruction
Q26768585Role of Bone Marrow-Derived Fibroblasts in Renal Fibrosis
Q38042110Role of GLP-1 and DPP-4 in diabetic nephropathy and cardiovascular disease
Q37959379Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects
Q40444286Role of angiotensin II in the tubulointerstitial fibrosis of obstructive nephropathy
Q37510401Role of angiotensin II type 1a receptor in renal injury induced by deoxycorticosterone acetate-salt hypertension
Q28379067Role of complement in acute tubulointerstitial injury of rats with aminonucleoside nephrosis
Q43174142Role of mast cells, stem cell factor and protease-activated receptor-2 in tubulointerstitial lesions in IgA nephropathy
Q40810538Role of myofibroblasts and collagen type IV in patients of IgA nephropathy as markers of renal dysfunction
Q54479244Role of non-HLA genetic variants in end-stage renal disease.
Q39251967SOCS-3 is downregulated in progressive CKD patients and regulates proliferation in human renal proximal tubule cells in a STAT1/3 independent manner
Q44901266Secretion of collagen type IV by human renal fibroblasts is increased by high glucose via a TGF-beta-independent pathway
Q73683748Selective antagonism of the AT1 receptor inhibits angiotensin II stimulated DNA and protein synthesis in primary cultures of human proximal tubular cells
Q34254623Serum bicarbonate concentrations and kidney disease progression in community-living elders: the Health, Aging, and Body Composition (Health ABC) Study
Q40649478Serum level of proximal renal tubular epithelial cell-binding immunoglobulin G in patients with lupus nephritis
Q52841623Serum uromodulin-a marker of kidney function and renal parenchymal integrity.
Q60956552ShenShuai II Recipe Attenuates Apoptosis and Renal Fibrosis in Chronic Kidney Disease by Increasing Renal Blood Flow and Improving Oxygen Consumption
Q38350669Sickle cell disease: renal manifestations and mechanisms
Q73181312Significance of mesangial expression of alpha-smooth muscle actin in the progression of IgA nephropathy
Q36304756Sirtuins and renal diseases: relationship with aging and diabetic nephropathy
Q34160971Soluble biglycan as a biomarker of inflammatory renal diseases
Q53076761Soluble klotho as a marker of renal fibrosis and podocyte injuries in human kidneys.
Q38731775Stearoyl-CoA Desaturase-1 Protects Cells against Lipotoxicity-Mediated Apoptosis in Proximal Tubular Cells
Q73321126Stenosis of the tubular neck: a possible mechanism for progressive renal failure
Q73504532Stenotic glomerulotubular necks in radiation nephropathy
Q44240129Study on the relationship between blood stasis syndrome and clinical pathology in 227 patients with primary glomerular disease
Q72473993Sustained expression of TGF-beta 1 underlies development of progressive kidney fibrosis
Q54667831TGF-beta1-induced connective tissue growth factor (CCN2) expression in human renal proximal tubule epithelial cells requires Ras/MEK/ERK and Smad signalling.
Q36908400Targeting pericyte differentiation as a strategy to modulate kidney fibrosis in diabetic nephropathy
Q47817742The IL-4 receptor α has a critical role in bone marrow-derived fibroblast activation and renal fibrosis
Q45967786The JNK Signaling Pathway in Renal Fibrosis.
Q94453152The MicroRNA MiR-29c Alleviates Renal Fibrosis via TPM1-Mediated Suppression of the Wnt/β-Catenin Pathway
Q28297657The Na(+)/glucose cotransporters: from genes to therapy
Q36299959The Pathogenesis and Therapeutic Implications of Tubulointerstitial Inflammation in Human Lupus Nephritis
Q88984435The Prognostic Value of Histopathologic Lesions in Native Kidney Biopsy Specimens: Results from the Boston Kidney Biopsy Cohort Study
Q36245167The aging kidney: a review -- part I.
Q33831294The association between age and nephrosclerosis on renal biopsy among healthy adults
Q38224257The biological significance of angiotensin-converting enzyme inhibition to combat kidney fibrosis
Q36485238The complex role of PPARgamma in renal dysfunction in obesity: managing a Janus-faced receptor
Q40357523The differential role of Smad2 and Smad3 in the regulation of pro-fibrotic TGFbeta1 responses in human proximal-tubule epithelial cells.
Q40561968The effect of high glucose and PPAR-gamma agonists on PPAR-gamma expression and function in HK-2 cells
Q28397401The effects of environmental chemicals on renal function
Q47833047The effects of grape seed on apoptosis-related gene expression and oxidative stress in streptozotocin-induced diabetic rats
Q37738159The emerging role of biomarkers in diabetic and hypertensive chronic kidney disease.
Q36612823The expression of cytoskeletal proteins in kidney specimens of children with primary focal segmental glomerulosclerosis
Q33995681The interaction of LFA-1 on mononuclear cells and ICAM-1 on tubular epithelial cells accelerates TGF-β1-induced renal epithelial-mesenchymal transition
Q40597024The many masks of focal segmental glomerulosclerosis
Q92503838The many talents of transforming growth factor-β in the kidney
Q42376166The proteasome inhibitor bortezomib attenuates renal fibrosis in mice via the suppression of TGF-β1.
Q45960411The relationship among renal injury, changed activity of renal 1-alpha hydroxylase and bone loss in elderly rats with insulin resistance or Type 2 diabetes mellitus.
Q46670531The relationship between renal injury and change in vitamin D metabolism in aged rats with insulin resistance or type 2 diabetes mellitus
Q39812927The role of Sirt1 in renal rejuvenation and resistance to stress
Q38233128The role of adenosine receptors A2A and A2B signaling in renal fibrosis
Q37488989The role of angiopoietin-1 in kidney disease
Q26851073The role of autophagy in the pathogenesis of diabetic nephropathy
Q52688968The role of renal dipeptidyl peptidase-4 in kidney disease: renal effects of dipeptidyl peptidase-4 inhibitors with a focus on linagliptin.
Q40184915The role played by endocytosis in albumin-induced secretion of TGF-beta1 by proximal tubular epithelial cells
Q33492379The time-dependence of long-term prediction in lupus nephritis
Q43686100Thrombospondin-1 short hairpin RNA suppresses tubulointerstitial fibrosis in the kidney of ureteral obstruction by ameliorating peritubular capillary injury
Q64921739Total Extracts of Abelmoschus manihot L. Attenuates Adriamycin-Induced Renal Tubule Injury via Suppression of ROS-ERK1/2-Mediated NLRP3 Inflammasome Activation.
Q73338092Transforming growth factor beta 1 and renal injury following subtotal nephrectomy in the rat: role of the renin-angiotensin system
Q47816856Transforming growth factor-beta in renal disease with glycogen storage disease I.
Q38585776Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury
Q40444278Tubulointerstitial damage in glomerular diseases: Its role in the progression of renal damage
Q42007739Tubulointerstitial disease in glomerulonephritis. Potential role of osteopontin (uropontin).
Q35766363Tubulointerstitial injury induced in rats by a monoclonal antibody that inhibits function of a membrane inhibitor of complement
Q42526002Tubulointerstitial responses in the progression of glomerular diseases: albuminuria modulates alpha v beta 5 integrin
Q51736584Type I interferon signaling is involved in the spontaneous development of lupus-like disease in B6.Nba2 and (B6.Nba2 x NZW)F(1) mice.
Q54262576Unique changes in interstitial extracellular matrix composition are associated with rejection and cyclosporine toxicity in human renal allograft biopsies.
Q46158716Up-regulated renal expression of TNF-alpha signalling adapter proteins in lupus glomerulonephritis
Q51758089Urinary Biomarkers of Kidney Tubular Damage and Risk of Cardiovascular Disease and Mortality in Elders.
Q92791402Urinary Biomarkers of Tubular Damage Are Associated with Mortality but Not Cardiovascular Risk among Systolic Blood Pressure Intervention Trial Participants with Chronic Kidney Disease
Q91975634Urinary Cell Adhesion Molecule 1 Is a Novel Biomarker That Links Tubulointerstitial Damage to Glomerular Filtration Rates in Chronic Kidney Disease
Q90723740Urinary Epidermal Growth Factor/Creatinine Ratio and Graft Failure in Renal Transplant Recipients: A Prospective Cohort Study
Q37164509Urinary L-type fatty acid-binding protein can reflect renal tubulointerstitial injury.
Q35188531Urinary NGAL is a useful clinical biomarker of HIV-associated nephropathy
Q33693244Urinary biomarkers: recommendations of the Joint European/United States Workshop for future research
Q52670608Urinary clusterin-a novel urinary biomarker associated with pediatric lupus renal histopathologic features and renal survival.
Q44471144Urinary excretion of complement C3d in patients with renal diseases
Q35103241Urinary excretion of fatty acid-binding protein reflects stress overload on the proximal tubules
Q37162318Urinary fatty acid-binding protein 1: an early predictive biomarker of kidney injury.
Q87945171Urinary neopterin: an immune activation marker in mesangial proliferative glomerulonephritis
Q54682142Urinary proteins from patients with nephrotic syndrome alters the signalling proteins regulating epithelial-mesenchymal transition.
Q46233386Urine Anion Gap to Predict Urine Ammonium and Related Outcomes in Kidney Disease
Q36104818Urine Collagen Fragments and CKD Progression-The Cardiovascular Health Study
Q38777914Urine Fibrosis Markers and Risk of Allograft Failure in Kidney Transplant Recipients: A Case-Cohort Ancillary Study of the FAVORIT Trial
Q89947074Urine Markers of Kidney Tubule Cell Injury and Kidney Function Decline in SPRINT Trial Participants with CKD
Q40175496Wen-pi-tang-Hab-Wu-ling-san, an oriental herbal prescription, attenuates epithelial-mesenchymal transdifferentiation stimulated by TGF-beta1 in kidney cells
Q33737756miR-200b precursor can ameliorate renal tubulointerstitial fibrosis
Q34305490p66Shc mediates high-glucose and angiotensin II-induced oxidative stress renal tubular injury via mitochondrial-dependent apoptotic pathway
Q42905735siRNAs targeted to Smad4 prevent renal fibrosis in vivo

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