Mechanistic implications for the use and monitoring of recombinant activated factor VII in trauma

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Mechanistic implications for the use and monitoring of recombinant activated factor VII in trauma is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1020458276
P356DOI10.1186/CC3781
P932PMC publication ID3226119
P698PubMed publication ID16221315
P5875ResearchGate publication ID7545505

P2093author name stringMyung S Park
Anthony E Pusateri
P2860cites workEffect of recombinant activated factor VII on perioperative blood loss in patients undergoing retropubic prostatectomy: a double-blind placebo-controlled randomised trialQ78840677
The use of recombinant factor VIIa in severe postpartum hemorrhageQ80344979
Recombinant factor VIIa increases the pressure at which rebleeding occurs in porcine uncontrolled aortic hemorrhage modelQ80347296
Effect of recombinant FVIIa in hypothermic, coagulopathic pigs with liver injuriesQ81050421
Effects of increasing doses of activated recombinant factor VII on haemostatic parameters in swineQ81402653
Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaqueQ24339425
The calibrated automated thrombogram (CAT): a universal routine test for hyper- and hypocoagulabilityQ28165369
A cell-based model of hemostasisQ28204461
Role of platelet P-selectin and microparticle PSGL-1 in thrombus formationQ28254159
The tissue factor pathway: how it has become a "prima ballerina"Q28631248
The endothelial cell ecto-ADPase responsible for inhibition of platelet function is CD39.Q30448825
Recombinant activated factor VII used in a man with refractory bleeding from a stab wound injuring the liver and kidneyQ33204161
Thrombin facilitates primary platelet adhesion onto vascular surfaces in the absence of plasma adhesive proteins: studies under flow conditionsQ33331699
Transfusion medicine service policies for recombinant factor VIIa administrationQ33362187
Recombinant factor VIIa enhances platelet adhesion and activation under flow conditions at normal and reduced platelet countQ33365901
Activated factor VII activates factors IX and X on the surface of activated platelets: thoughts on the mechanism of action of high-dose activated factor VII.Q33504352
Biochemistry and physiology of blood coagulation.Q33799936
The regulation of the factor VII-dependent coagulation pathway: rationale for the effectiveness of recombinant factor VIIa in refractory bleeding disordersQ34090256
WATERFALL SEQUENCE FOR INTRINSIC BLOOD CLOTTING.Q34257361
Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammationQ34303816
The use of recombinant factor VIIa in the treatment of bleeding disorders.Q34343186
Recombinant activated factor VII (rFVIIa): characterization, manufacturing, and clinical developmentQ34362575
The action of high-dose factor VIIa (FVIIa) in a cell-based model of hemostasis.Q34458071
Disseminated intravascular coagulation in trauma patientsQ34461301
Factor XI activation in a revised model of blood coagulationQ34500136
Successful use of recombinant activated factor VII for trauma-associated hemorrhage in a patient without preexisting coagulopathyQ34522223
Activation of factor IX by the reaction product of tissue factor and factor VII: additional pathway for initiating blood coagulationQ35047906
Treating coagulopathy in trauma patientsQ35185225
Monitoring coagulation and the clinical effects of recombinant factor VIIaQ35661480
Views on methods for monitoring recombinant factor VIIa in inhibitor patientsQ35661495
Effects of recombinant activated factor VII on coagulation measured by thromboelastography in liver transplantationQ62107359
Activation of human factor V by factor Xa and thrombinQ68747564
Tissue factor pathway inhibitorQ70943593
Transmission of a procoagulant signal from tissue factor-bearing cell to plateletsQ71612091
A model for the tissue factor pathway to thrombin. I. An empirical studyQ72181568
Recombinant factor VIIa in orthotopic liver transplantation: influence on parameters of coagulation and fibrinolysisQ73114039
Activated recombinant factor VII for control of diffuse bleeding after implantation of ventricular assist deviceQ73142092
The use of recombinant factor VIIa in children with inherited platelet function disordersQ73320925
Comparison of PFA-100 and bleeding time testing in pediatric patients with suspected hemorrhagic problemsQ73497164
Mechanism of action of recombinant factor VIIaQ73690484
Combined fresh frozen plasma with recombinant factor VIIa in restoring hemostasis for invasive procedures in children with liver diseasesQ73848430
Recombinant factor VIIa corrects prothrombin time in cirrhotic patients: a preliminary studyQ73933603
An effective treatment of severe intractable bleeding after valve repair by one single dose of activated recombinant factor VIIQ74268022
Recombinant factor VIIa treatment of bleeding associated with acute renal failureQ74346045
The use of recombinant activated factor VII to control bleeding in a preterm infant undergoing exploratory laparotomyQ74398520
Safety and efficacy of recombinant factor VIIa in patients with liver disease undergoing laparoscopic liver biopsyQ74428289
Synthetic factor VIIa to treat dilutional coagulopathy during posterior spinal fusion in two childrenQ74593898
Successful use of recombinant activated factor VII (Novoseven) in controlling severe intra-abdominal bleeding after liver needle biopsyQ77670272
The effect of recombinant factor VIIa (NovoSeven) in healthy volunteers receiving acenocoumarol to an International Normalized Ratio above 2.0.Q77800200
Marked temperature dependence of the platelet calcium signal induced by human von Willebrand factorQ77920757
Understanding the hemostatic effects of recombinant factor VIIa by clot wave form analysisQ35661530
Thromboelastography and recombinant factor VIIa-hemophilia and beyondQ35661536
Recombinant factor VIIa: review of efficacy, dosing regimens and safety in patients with congenital and acquired factor VIII or IX inhibitorsQ35771690
Recombinant activated factor VII (NovoSeven): addition to replacement therapy in acute, uncontrolled and life-threatening bleedingQ35839531
Recombinant Factor VIIa: clinical applications for an intravenous hemostatic agent with broad-spectrum potentialQ35879063
Treating traumatic bleeding in a combat setting: possible role of recombinant activated factor VII.Q36009737
Use of human factor VIIa in the treatment of two hemophilia A patients with high-titer inhibitorsQ36990492
Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis.Q42138675
Modulation of endothelial cell hemostatic properties by tumor necrosis factorQ42151543
Intravenous rFVIIa administered for hemorrhage control in hypothermic coagulopathic swine with grade V liver injuriesQ43575604
Extracellular pH affects platelet aggregation associated with modulation of store-operated Ca(2+) entryQ43818632
Capacitative calcium influx and intracellular pH cross-talk in human plateletsQ44353415
Recombinant activated factor VII combined with local measures in preventing bleeding from invasive dental procedures in patients with Glanzmann thrombastheniaQ44359025
Recombinant activated factor VII for adjunctive hemorrhage control in traumaQ44472174
Factor VIIa for correction of traumatic coagulopathyQ45130198
Early injection of high-dose recombinant factor VIIa decreases blood loss and prolongs time from injury to death in experimental liver injuryQ45857141
Influence of factor VIIa and phospholipids on coagulation in "acquired" hemophiliaQ45857666
Possible role of recombinant activated factor VII (rFVIIa) in the control of hemorrhage associated with massive trauma.Q45858062
The Effect of Recombinant Factor VIIa on Noncoagulopathic Pigs with Grade V Liver InjuriesQ45862242
Recombinant activated factor VII for the rapid correction of coagulopathy in nonhemophilic neurosurgical patientsQ45863098
How factor VIIa works in hemophiliaQ45863820
The role of recombinant factor VIIa (FVIIa) in fibrin structure in the absence of FVIII/FIX.Q45863825
Whole blood coagulation thrombelastographic profiles employing minimal tissue factor activationQ45863892
Whole blood clot formation phenotypes in hemophilia A and rare coagulation disorders. Patterns of response to recombinant factor VIIaQ45871588
A comparison of FVII:C and FVIIa assays for the monitoring of recombinant factor VIIa treatmentQ45873675
Pharmacokinetics of activated recombinant coagulation factor VII (NovoSeven) in children vs. adults with haemophilia A.Q45876353
Recombinant factor VIIa: a general hemostatic agent? Yes.Q45878443
Recombinant factor VIIa: a general hemostatic agent? Not yet.Q45878448
Successful treatment of severe intra-abdominal bleeding associated with disseminated intravascular coagulation using recombinant activated factor VII.Q45878840
Inhibition of fibrinolysis by recombinant factor VIIa in plasma from patients with severe hemophilia A.Q45882175
Guidelines for the use of recombinant activated factor VII (rFVIIa) in uncontrolled bleeding: a report by the Israeli Multidisciplinary rFVIIa Task ForceQ45882922
Factor VIIa-catalyzed activation of factor X independent of tissue factor: its possible significance for control of hemophilic bleeding by infused factor VIIaQ45883227
Clinical experience with human plasma-derived factor VIIa in patients with hemophilia A and high titer inhibitorsQ45884134
Mechanism by which recombinant factor VIIa shortens the aPTT: activation of factor X in the absence of tissue factorQ45884478
Platelet activity of high-dose factor VIIa is independent of tissue factorQ45884609
The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuriesQ45888438
Injury induces increased monocyte expression of tissue factor: factors associated with head injury attenuate the injury-related monocyte expression of tissue factorQ46512576
Recombinant activated factor VII for the treatment of life-threatening haemorrhageQ47388493
Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials.Q50758503
Recombinant coagulation factor VIIa in major liver resection: a randomized, placebo-controlled, double-blind clinical trial.Q50775941
A model for the tissue factor pathway to thrombin. II. A mathematical simulation.Q52371258
Preliminary experience with the use of recombinant factor VIIa to treat coagulation disturbances in pediatric patients.Q53304056
Treatment of excessive bleeding in Jehovah's Witness patients after cardiac surgery with recombinant factor VIIa (NovoSeven).Q53386785
Treatment of traumatic bleeding with recombinant factor VIIa.Q55033461
Population pharmacokinetics of recombinant factor VIIa in volunteers anticoagulated with acenocoumarol.Q55067704
The Effect of Temperature and pH on the Activity of Factor VIIa: Implications for the Efficacy of High-Dose Factor VIIa in Hypothermic and Acidotic PatientsQ61405306
P921main subjectblood coagulationQ179217
injuryQ193078
zymogenQ245759
protein precursorQ258658
blood proteinsQ425056
biomedical investigative techniqueQ66648976
P304page(s)S15-24
P577publication date2005-10-07
P1433published inCritical CareQ5186602
P1476titleMechanistic implications for the use and monitoring of recombinant activated factor VII in trauma
P478volume9 Suppl 5

Reverse relations

cites work (P2860)
Q33282917Failure of recombinant factor VIIa in a patient with severe polymicrobial sepsis and postoperative uncontrolled intraabdominal bleeding
Q37117872Hemostatic therapy for the treatment of intracranial hemorrhage
Q38267207NovoSeven (recombinant factor VIIa) for the treatment of bleeding episodes and perioperative management in patients with Glanzmann's thrombasthenia
Q33375346Pharmacology and clinical use of recombinant activated factor seven in neurosciences
Q33372308Prophylactic recombinant factor VIIa administration to an infant with congenital systemic juvenile xanthogranuloma
Q34005911Recombinant factor VII is associated with worse survival in complex cardiac surgical patients
Q36152281Thromboelastography as a better indicator of hypercoagulable state after injury than prothrombin time or activated partial thromboplastin time

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