scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | LeBris S Quinn | |
Charles T Lutz | |||
P2860 | cites work | Interleukin-15 and its soluble receptor mediate the response to infliximab in patients with Crohn's disease | Q83058286 |
Aging is associated with circulating cytokine dysregulation | Q83404918 | ||
The association between the ratio of visceral fat to thigh muscle area and metabolic syndrome: the Korean Sarcopenic Obesity Study (KSOS) | Q84552637 | ||
Bariatric Surgery Reverses Natural Killer (NK) Cell Activity and NK-Related Cytokine Synthesis Impairment Induced by Morbid Obesity | Q84965480 | ||
General and Abdominal Adiposity and Risk of Death in Europe | Q22250882 | ||
Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins | Q24294612 | ||
Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor | Q24313035 | ||
Pre-B cell colony-enhancing factor inhibits neutrophil apoptosis in experimental inflammation and clinical sepsis | Q24568212 | ||
The renal handling of low molecular weight proteins. II. Disorders of serum protein catabolism in patients with tubular proteinuria, the nephrotic syndrome, or uremia | Q24630588 | ||
Narrative review: the role of leptin in human physiology: emerging clinical applications | Q24634811 | ||
Obesity is associated with macrophage accumulation in adipose tissue | Q27860976 | ||
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance | Q28131660 | ||
The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens | Q28198712 | ||
Frailty in older adults: evidence for a phenotype | Q28205094 | ||
Decreased natural killer cell activity is associated with atherosclerosis in elderly humans | Q28209773 | ||
IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells | Q28214975 | ||
Age-related changes in the structure and function of skeletal muscles | Q28249640 | ||
Interleukin-10 and related cytokines and receptors | Q28251518 | ||
Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist | Q28273130 | ||
Transforming growth factor-beta regulation of immune responses | Q28303115 | ||
Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long calorie restriction | Q28569873 | ||
Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice | Q28594052 | ||
Obesity induces a phenotypic switch in adipose tissue macrophage polarization | Q29547686 | ||
Prevalence and trends in obesity among US adults, 1999-2008 | Q29547759 | ||
Adipocytokines: mediators linking adipose tissue, inflammation and immunity | Q29619393 | ||
Immunological and inflammatory functions of the interleukin-1 family | Q29619669 | ||
Are natural killer cells protecting the metabolically healthy obese patient? | Q30375124 | ||
Resistance of Janus kinase-2 dependent leptin signaling in natural killer (NK) cells: a novel mechanism of NK cell dysfunction in diet-induced obesity | Q33324814 | ||
A standard procedure for creating a frailty index. | Q33372958 | ||
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cells | Q36985100 | ||
Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases. | Q37056669 | ||
IL-15 trans-presentation promotes human NK cell development and differentiation in vivo | Q37061837 | ||
Oversecretion of interleukin-15 from skeletal muscle reduces adiposity | Q37086430 | ||
Sarcopenic obesity and inflammation in the InCHIANTI study | Q37104446 | ||
Killer cells in chronic obstructive pulmonary disease | Q37108638 | ||
IL-6 promotes NK cell production of IL-17 during toxoplasmosis | Q37132980 | ||
Aging of the immune system as a prognostic factor for human longevity | Q37133613 | ||
Nampt: linking NAD biology, metabolism and cancer | Q37334248 | ||
The expression of TNF alpha by human muscle. Relationship to insulin resistance | Q37352139 | ||
A potential role for interleukin-15 in the regulation of human natural killer cell survival | Q37364381 | ||
Longitudinal study of muscle strength, quality, and adipose tissue infiltration | Q37421196 | ||
Differential patterns of serum concentration and adipose tissue expression of chemerin in obesity: adipose depot specificity and gender dimorphism. | Q37461739 | ||
The diseasome of physical inactivity--and the role of myokines in muscle--fat cross talk | Q37596777 | ||
Trans-presentation: a novel mechanism regulating IL-15 delivery and responses | Q37612151 | ||
Distinct cell types control lymphoid subset development by means of IL-15 and IL-15 receptor alpha expression | Q37682391 | ||
Sarcopenia: characteristics, mechanisms and functional significance | Q37702014 | ||
The interaction between adipokines, diet and exercise on muscle insulin sensitivity | Q37705987 | ||
Transcriptional control of natural killer cell development and function | Q37875298 | ||
Chemerin and its receptors in leukocyte trafficking, inflammation and metabolism. | Q37961295 | ||
The inflammasome puts obesity in the danger zone | Q37973832 | ||
High-dose leptin activates human leukocytes via receptor expression on monocytes. | Q38295956 | ||
Short-term and long-term leptin exposure differentially affect human natural killer cell immune functions | Q38331523 | ||
IL-10 restricts activation-induced death of NK cells during acute murine cytomegalovirus infection | Q38445112 | ||
The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha | Q39957205 | ||
Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity | Q40041302 | ||
Overexpression of interleukin-15 induces skeletal muscle hypertrophy in vitro: implications for treatment of muscle wasting disorders. | Q40698711 | ||
Tumor necrosis factor, other cytokines and disease | Q40800572 | ||
Cytokine-induced apoptosis of human natural killer cells identifies a novel mechanism to regulate the innate immune response. | Q41131020 | ||
Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue. | Q41893697 | ||
Adiponectin is a negative regulator of NK cell cytotoxicity. | Q42494633 | ||
Impaired natural killer (NK) cell activity in leptin receptor deficient mice: leptin as a critical regulator in NK cell development and activation | Q42527523 | ||
Chronic high fat feeding attenuates load-induced hypertrophy in mice. | Q43263022 | ||
Characteristics of peripheral and peritoneal white blood cells in children with chronic renal failure, dialyzed or not. | Q43411458 | ||
TNF-alpha-induced apoptosis in human naïve and memory CD8+ T cells in aged humans | Q43505439 | ||
The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo. | Q43648190 | ||
Resistin, central obesity, and type 2 diabetes. | Q43865215 | ||
Association of low interleukin-10 levels with the metabolic syndrome in obese women | Q44357201 | ||
IL-6 enhances plasma IL-1ra, IL-10, and cortisol in humans | Q44511071 | ||
Cytokines and chemokines are both expressed by human myoblasts: possible relevance for the immune pathogenesis of muscle inflammation | Q45870452 | ||
Pivotal role of endogenous TNF-alpha in the induction of functional inactivation and apoptosis in NK cells. | Q46005898 | ||
Macrophage- and dendritic-cell-derived interleukin-15 receptor alpha supports homeostasis of distinct CD8+ T cell subsets | Q46076652 | ||
Association between interleukin-15 and obesity: interleukin-15 as a potential regulator of fat mass | Q46433459 | ||
Is visfatin an adipokine or myokine? Evidence for greater visfatin expression in skeletal muscle than visceral fat in chickens | Q46838475 | ||
Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity | Q47861318 | ||
A programmed switch from IL-15- to IL-2-dependent activation in human NK cells. | Q47884291 | ||
Plasma cytokine profiles in elderly humans | Q47953047 | ||
Upregulation of circulating IL-15 by treadmill running in healthy individuals: is IL-15 an endocrine mediator of the beneficial effects of endurance exercise? | Q48288330 | ||
Serum leptin concentrations and markers of immune function in overweight or obese postmenopausal women. | Q48877385 | ||
Muscles and their myokines. | Q48943557 | ||
The role of leptin resistance in the lipid abnormalities of aging. | Q49099661 | ||
No requirement of trans presentations of IL-15 for human CD8 T cell proliferation. | Q51034844 | ||
Exercise and IL-6 infusion inhibit endotoxin-induced TNF-alpha production in humans. | Q54529003 | ||
Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. | Q55041597 | ||
Prevalence of High Body Mass Index in US Children and Adolescents, 2007-2008 | Q56621069 | ||
The Soluble Chain of Interleukin-15 Receptor: A Proinflammatory Molecule Associated with Tumor Progression in Head and Neck Cancer | Q56965945 | ||
An Immune Risk Phenotype, Cognitive Impairment, and Survival in Very Late Life: Impact of Allostatic Load in Swedish Octogenarian and Nonagenarian Humans | Q56986846 | ||
T-ing up inflammation in fat | Q58197131 | ||
IL-15 is an essential mediator of peripheral NK-cell homeostasis | Q58478746 | ||
Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study | Q59538331 | ||
Aging, muscle fiber type, and contractile function in sprint-trained athletes | Q60248239 | ||
Interleukin-15 treatment improves glucose homeostasis and insulin sensitivity in obese mice | Q61911883 | ||
Interleukin-15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes | Q61911892 | ||
Expression of type I insulin-like growth factor receptors on human peripheral blood mononuclear cells | Q67575198 | ||
Increased number of circulating Leu 11+ (CD 16) large granular lymphocytes and decreased NK activity during human ageing | Q68828979 | ||
Effect of age on muscle hypertrophy induced by resistance training | Q71770861 | ||
Insulin-like growth factor-I enhances lymphoid and myeloid reconstitution after allogeneic bone marrow transplantation | Q73582357 | ||
Interleukin-1beta costimulates interferon-gamma production by human natural killer cells | Q73592489 | ||
Influence of obesity on immune function | Q74603878 | ||
Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA immune study | Q77436737 | ||
IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation | Q77658417 | ||
Natural killer cell activity and sensitivity to positive and negative modulation in uncomplicated obese subjects: relationships to leptin and diet composition | Q80224114 | ||
Association of interleukin-15 protein and interleukin-15 receptor genetic variation with resistance exercise training responses | Q80974916 | ||
Distribution and determinants of adiponectin, resistin and ghrelin in a randomly selected healthy population | Q81103628 | ||
The unresponsiveness of aged mice to polysaccharide antigens is a result of a defect in macrophage function | Q81224629 | ||
Resistin, an adipokine with potent proinflammatory properties | Q81672242 | ||
Mononuclear phagocyte-derived IL-10 suppresses the innate IL-12/IFN-gamma axis in lung-challenged aged mice | Q81803366 | ||
Fifth phase of the epidemiologic transition: the age of obesity and inactivity | Q82494700 | ||
Skeletal muscle NAMPT is induced by exercise in humans | Q33589034 | ||
Serum and muscle interleukin-15 levels decrease in aging mice: correlation with declines in soluble interleukin-15 receptor alpha expression | Q33624343 | ||
Aging of the innate immune system | Q33666891 | ||
Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo | Q33760403 | ||
NK and NK/T cells in human senescence | Q33846328 | ||
Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population | Q33928216 | ||
Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticity | Q33934522 | ||
Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation | Q33946323 | ||
Sarcopenic obesity: does muscle loss cause fat gain? Lessons from rheumatoid arthritis and osteoarthritis. | Q33949591 | ||
Correlation between serum resistin level and adiposity in obese individuals | Q33967739 | ||
The functional characterization of interleukin-10 receptor expression on human natural killer cells. | Q34294025 | ||
Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates | Q34369832 | ||
Excess deaths associated with underweight, overweight, and obesity | Q34412581 | ||
Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation. | Q34426034 | ||
Adipose tissues as an ancestral immune organ: site-specific change in obesity. | Q34426141 | ||
Interleukin 6 as a key regulator of muscle mass during cachexia | Q34727530 | ||
Human NK cells proliferate and die in vivo more rapidly than T cells in healthy young and elderly adults | Q34765436 | ||
Normalizing a hyperactive mTOR initiates muscle growth during obesity | Q34852371 | ||
Age-related modifications in circulating IL-15 levels in humans | Q34894566 | ||
Inflammatory markers in population studies of aging | Q34995451 | ||
Interleukin-15 administration improves diaphragm muscle pathology and function in dystrophic mdx mice | Q35083822 | ||
Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-gamma in inflammation in human adipose tissue | Q35147250 | ||
Hypoxia-induced inflammatory cytokine secretion in human adipose tissue stromovascular cells | Q35175008 | ||
One size may not fit all: anti-aging therapies and sarcopenia | Q35740777 | ||
Circulating IL-15 exists as heterodimeric complex with soluble IL-15Rα in human and mouse serum | Q36079820 | ||
Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice | Q36278695 | ||
Interleukin (IL)-15Rα–deficient Natural Killer Cells Survive in Normal but Not IL-15Rα–deficient Mice | Q36370673 | ||
In vivo survival and homeostatic proliferation of natural killer cells. | Q36370683 | ||
Cachexia: pathophysiology and clinical relevance | Q36442937 | ||
Grip strength and the metabolic syndrome: findings from the Hertfordshire Cohort Study. | Q36538004 | ||
IL-15Ralpha chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation | Q36640049 | ||
Interleukin-15 antagonizes muscle protein waste in tumour-bearing rats | Q36642208 | ||
Association between muscular strength and mortality in men: prospective cohort study. | Q36755864 | ||
Interleukin-15: a muscle-derived cytokine regulating fat-to-lean body composition | Q36914800 | ||
P275 | copyright license | Creative Commons Attribution 2.5 Generic | Q18810333 |
P433 | issue | 8 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | peptide | Q172847 |
sarcopenia | Q1787939 | ||
cell | Q7868 | ||
hormone | Q11364 | ||
adipokine | Q2638593 | ||
cellular senescence | Q9075999 | ||
obesity | Q12174 | ||
hemic and immune systems | Q70202933 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 535-546 | |
P577 | publication date | 2012-08-01 | |
P1433 | published in | Aging | Q2845875 |
P1476 | title | Sarcopenia, obesity, and natural killer cell immune senescence in aging: altered cytokine levels as a common mechanism | |
P478 | volume | 4 |
Q64095960 | A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable |
Q47698223 | Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults |
Q34089694 | Aging and HIV/AIDS: pathogenetic role of therapeutic side effects |
Q37610201 | Aging promotes neoplastic disease through effects on the tissue microenvironment. |
Q57214119 | Association between Sarcopenia, Sarcopenic Obesity, and Chronic Disease in Korean Elderly |
Q92005939 | Association of loss of muscle mass with mortality in liver cirrhosis without or before liver transplantation: A systematic review and meta-analysis |
Q91589968 | Association of sarcopenic obesity with the risk of all-cause mortality among adults over a broad range of different settings: a updated meta-analysis |
Q50249564 | Body composition of the host influences dendritic cell phenotype in patients treated for colorectal cancer. |
Q35769609 | Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity. |
Q42365245 | Changes of peripheral lymphocyte subsets and cytokine environment during aging and deteriorating gastrointestinal tract health status |
Q52565362 | Clinical Impact of Preoperative Sarcopenia on the Postoperative Outcomes After Pancreas Transplantation. |
Q36189078 | Comparison of rapamycin schedules in mice on high-fat diet |
Q90704970 | Decreased Incidence of Acute Cellular Rejection in Low-Muscle-Mass Recipients After Living-donor Liver Transplantation |
Q52934359 | Effect of tamoxifen on fatty degeneration and atrophy of rotator cuff muscles in chronic rotator cuff tear: An animal model study. |
Q99630301 | Effects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training |
Q97527435 | Exosomes derived from human umbilical cord MSCs rejuvenate aged MSCs and enhance their functions for myocardial repair |
Q37577484 | FoxO1 controls lysosomal acid lipase in adipocytes: implication of lipophagy during nutrient restriction and metformin treatment |
Q47135584 | High Intensity Interval Training Increases Natural Killer Cell Number and Function in Obese Breast Cancer-challenged Mice and Obese Women |
Q53144250 | High-fat high-sucrose diet leads to dynamic structural and inflammatory alterations in the rat vastus lateralis muscle. |
Q51761092 | Human Body Composition and Immunity: Visceral Adipose Tissue Produces IL-15 and Muscle Strength Inversely Correlates with NK Cell Function in Elderly Humans. |
Q38722387 | IL-15 Activates the Jak3/STAT3 Signaling Pathway to Mediate Glucose Uptake in Skeletal Muscle Cells |
Q39293674 | IL-15 Mediates Mitochondrial Activity through a PPARδ-Dependent-PPARα-Independent Mechanism in Skeletal Muscle Cells. |
Q42374870 | IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development |
Q40245420 | Immune System Dysfunction in the Elderly. |
Q37115843 | Immunological and nutritional factors in elderly people in low-level care and their association with mortality |
Q90723538 | Impact of Body Composition on the Risk of Hepatocellular Carcinoma Recurrence After Liver Transplantation |
Q37077610 | Impact of HIV-1 tropism on the emergence of non-AIDS events in HIV-infected patients receiving fully suppressive antiretroviral therapy |
Q52962609 | Impact of Skeletal Muscle Mass, Muscle Quality, and Visceral Adiposity on Outcomes Following Resection of Intrahepatic Cholangiocarcinoma. |
Q49943276 | Impact of Visceral Adiposity as Well as Sarcopenic Factors on Outcomes in Patients Undergoing Liver Resection for Colorectal Liver Metastases. |
Q50239119 | Impact of postoperative changes in sarcopenic factors on outcomes after hepatectomy for hepatocellular carcinoma. |
Q38953534 | Impact of preoperative hand grip strength on morbidity following gastric cancer surgery |
Q44091902 | Impact of quality as well as quantity of skeletal muscle on outcomes after liver transplantation |
Q47394363 | Impact of sarcopenia on outcomes of locally advanced esophageal cancer patients treated with neoadjuvant chemoradiation followed by surgery |
Q57128317 | Impact of sarcopenia on outcomes of patients undergoing pancreatectomy: A retrospective analysis of 107 patients |
Q97519815 | Improvements to Healthspan Through Environmental Enrichment and Lifestyle Interventions: Where Are We Now? |
Q36053553 | Increased body mass index and adjusted mortality in ICU patients with sepsis or septic shock: a systematic review and meta-analysis |
Q40832684 | Influence of BMI on short-term surgical outcome after colorectal cancer surgery: a study based on the Swedish national quality registry |
Q50735752 | Is obesity a marker of robustness in vulnerable hospitalized aged populations? Prospective, multicenter cohort study of 1 306 acutely ill patients. |
Q37308200 | Killer Immunoglobulin-like Receptors (KIR) haplogroups A and B track with Natural Killer Cells and Cytokine Profile in Aged Subjects: Observations from Octo/Nonagenarians in the Belfast Elderly Longitudinal Free-living Aging STudy (BELFAST). |
Q90321930 | Long-Term Effects of Dietary Protein and Branched-Chain Amino Acids on Metabolism and Inflammation in Mice |
Q34722012 | Microbial shifts in the aging mouse gut. |
Q40717546 | Muscle Steatosis is an Independent Predictor of Postoperative Complications in Patients with Hepatocellular Carcinoma. |
Q53080352 | Natural killer (NK) cell deficit in coronary artery disease: no aberrations in phenotype but sustained reduction of NK cells is associated with low-grade inflammation. |
Q38633355 | Obesity-associated cancer: an immunological perspective |
Q38162295 | Obesity-related inflammation: implications for older adults |
Q42096731 | Parallel Profiles of Inflammatory and Effector Memory T Cells in Visceral Fat and Liver of Obesity-Associated Cancer Patients. |
Q89782645 | Phenotypes of Sarcopenic Obesity: Exploring the Effects on Peri-Muscular Fat, the Obesity Paradox, Hormone-Related Responses and the Clinical Implications |
Q50099246 | Posttherapeutic skeletal muscle mass recovery predicts favorable prognosis in patients with advanced urothelial carcinoma receiving first-line platinum-based chemotherapy. |
Q89484197 | Predictive Value of Preoperative Sarcopenia in Patients with Gastric Cancer: a Meta-analysis and Systematic Review |
Q61807868 | Predictive value of skeletal muscle mass for immunotherapy with nivolumab in non-small cell lung cancer patients: A "hypothesis-generator" preliminary report |
Q52983311 | Preoperative Sarcopenia Strongly Influences the Risk of Postoperative Pancreatic Fistula Formation After Pancreaticoduodenectomy. |
Q90288438 | Preoperative Visceral Adiposity and Muscularity Predict Poor Outcomes after Hepatectomy for Hepatocellular Carcinoma |
Q50438246 | Preoperative intramuscular adipose tissue content is a novel prognostic predictor after hepatectomy for hepatocellular carcinoma. |
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Q49907018 | Proposal for new selection criteria considering pre-transplant muscularity and visceral adiposity in living donor liver transplantation. |
Q33733721 | Radiographic sarcopenia predicts postoperative infectious complications in patients undergoing pancreaticoduodenectomy. |
Q37018247 | Rat retinal transcriptome: effects of aging and AMD-like retinopathy |
Q55026287 | Sarcopenia as a predictor of post-transplant tumor recurrence after living donor liver transplantation for hepatocellular carcinoma beyond the Milan criteria. |
Q40138785 | Sarcopenia is an independent predictor of complications after colorectal cancer surgery |
Q36804785 | Sarcopenic obesity and endocrinal adaptation with age |
Q26744102 | Selection Criteria and Current Issues in Liver Transplantation for Hepatocellular Carcinoma |
Q64263957 | Significance of preoperative sarcopenia to liver surgery |
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Q38218127 | Targeting T cell immunometabolism for cancer immunotherapy; understanding the impact of the tumor microenvironment. |
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Q64105293 | The Modulatory Effect of Gender and Cytomegalovirus-Seropositivity on Circulating Inflammatory Factors and Cognitive Performance in Elderly Individuals |
Q54957754 | The Relation between Sarcopenia and Mortality in Patients at Intensive Care Unit. |
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Q50798813 | [Gender aspects of malnutrition and associated sequelae. Prevention and therapy]. |
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