Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo

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Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1046112735
P356DOI10.1038/CDDIS.2014.465
P8608Fatcat IDrelease_otosi6nlmbbvlfldqzm25tvuue
P932PMC publication ID4649538
P698PubMed publication ID25356874
P5875ResearchGate publication ID267738358

P50authorCarlos F. MenckQ58336882
Veridiana MunfordQ80192568
Annabel QuinetQ86715015
P2093author name stringC C M Garcia
C R R Rocha
D B Vieira
J E Belizário
L C de Andrade-Lima
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Repair of O(6)-alkylguanine by alkyltransferasesQ33892810
Acquisition of chemoresistance in gliomas is associated with increased mitochondrial coupling and decreased ROS productionQ34023873
Role of Glutathione in the Regulation of Cisplatin Resistance in Cancer ChemotherapyQ34159386
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Chemoresistance of glioblastoma cancer stem cells--much more complex than expectedQ35521316
Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulationQ35818950
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γH2Ax: biomarker of damage or functional participant in DNA repair "all that glitters is not gold!".Q37924856
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Molecular mechanisms of temozolomide resistance in glioblastoma multiformeQ38010801
Induction of p53-mediated apoptosis and recovery of chemosensitivity through p53 transduction in human glioblastoma cells by cisplatinQ38512037
Novel XPG (ERCC5) mutations affect DNA repair and cell survival after ultraviolet but not oxidative stress.Q39223156
Inhibition of GSH synthesis potentiates temozolomide-induced bystander effect in glioblastomaQ39225065
The glutathione transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) increases temozolomide efficacy against malignant melanoma.Q39602310
Negative regulation of p53 by the long isoform of ErbB3 binding protein Ebp1 in brain tumorsQ39628667
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Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.Q40033543
Down-regulation of the inhibitor of growth 1 (ING1) tumor suppressor sensitizes p53-deficient glioblastoma cells to cisplatin-induced cell deathQ40086566
Augmentation of cisplatin sensitivity in cisplatin-resistant human bladder cancer cells by modulating glutathione concentrations and glutathione-related enzyme activitiesQ40433330
Sensitizing glioma cells to cisplatin by abrogating the p53 response with antisense oligonucleotidesQ40551019
Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines.Q40662296
Inhibition of glutathione synthesis reverses Bcl-2-mediated cisplatin resistanceQ40675325
Increased nucleotide excision repair in cisplatin-resistant ovarian cancer cells: role of ERCC1-XPF.Q40852256
Attenuation of O(6)-methylguanine-DNA methyltransferase activity and mRNA levels by cisplatin and temozolomide in jurkat cells.Q40867830
A phase II study of cisplatin and temozolomide in heavily pre-treated patients with temozolomide-refractory high-grade malignant gliomaQ43257160
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Prognostic significance of glutathione S-transferase pi expression and subcellular localization in human gliomasQ48350372
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanineQ48479768
Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer.Q54154484
DNA-adduct levels as a predictor of outcome for NSCLC patients receiving daily cisplatin and radiotherapyQ73645101
Prediction of treatment outcome by cisplatin-DNA adduct formation in patients with stage III/IV head and neck squamous cell carcinoma, treated by concurrent cisplatin-radiation (RADPLAT)Q82896468
Quantitative PCR-based measurement of nuclear and mitochondrial DNA damage and repair in mammalian cellsQ83285369
P4510describes a project that usesImageQuantQ112270642
P921main subjectglutathioneQ116907
temozolomideQ425088
P304page(s)e1505
P577publication date2014-10-30
P1433published inCell Death and DiseaseQ2197222
P1476titleGlutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.
P478volume5

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cites work (P2860)
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