Cytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia

scientific article

Cytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1005990488
P356DOI10.1038/BJC.1998.123
P932PMC publication ID2149964
P698PubMed publication ID9514054
P5875ResearchGate publication ID51310636

P2093author name stringM L Hauck
M R Zalutsky
P C Welsh
R H Larsen
P2860cites workHyperthermia-induced shedding and masking of melanoma-associated antigenQ68676502
Nonuniformity of tumor dose in radioimmunotherapyQ68694119
Phase I studies of treatment of malignant gliomas and neoplastic meningitis with 131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F (ab')2--a preliminary reportQ70790931
Generation and characterization of a mouse/human chimeric antibody directed against extracellular matrix protein tenascinQ71634453
Radioimmunotherapy of neoplastic meningitis in rats using an alpha-particle-emitting immunoconjugateQ72132787
Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycolurilQ29618344
Effect of cell arrangement and interstitial volume fraction on the diffusivity of monoclonal antibodies in tissueQ34092522
Segmental flexibility and complement fixation of genetically engineered chimeric human, rabbit and mouse antibodiesQ35981835
The distribution of alternative agents for targeted radiotherapy within human neuroblastoma spheroidsQ35983310
Penetration and binding of monoclonal antibody in human osteosarcoma multicell spheroids. Comparison of confocal laser scanning microscopy and autoradiographyQ36804731
Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convectionQ38606742
Interaction of Hyperthermia with Radiations of Different Linear Energy TransferQ40645481
131I-meta-iodobenzylguanidine therapy in neuroblastoma spheroids of different sizesQ41103159
An analysis of monoclonal antibody distribution in microscopic tumor nodules: consequences of a "binding site barrier".Q41161237
Radioimmunotherapy of prostatic adenocarcinomas: Effects of 131I‐labelled E4 antibodies on cells at different depth in DU 145 spheroidsQ41272853
Comparisons between two monoclonal antibodies that bind to the same antigen but have differing affinities: uptake kinetics and 125I-antibody therapy efficacy in multicell spheroidsQ41604323
Sensitization of rat 9L gliosarcoma cells to low dose rate irradiation by long duration 41 degrees C hyperthermiaQ41679280
Iodine-125-NRLU-10 kinetic studies and bismuth-212-NRLU-10 toxicity in LS174T multicell spheroids.Q41722184
A tumour spheroid model for antibody-targeted therapy of micrometastasesQ43050172
Enhancement of monoclonal antibody binding to melanoma with single dose radiation or hyperthermiaQ43707827
Elimination of dose-rate effects by mild hyperthermiaQ45252096
Diffusion and binding of monoclonal antibody TNT-1 in multicellular tumor spheroidsQ47573832
The effects of hyperthermia on tumor carcinoembryonic antigen expressionQ47581686
Specific chromosomal abnormalities in malignant human gliomasQ48122890
Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model.Q55478835
The effects of clinically relevant hyperthermic temperatures on the kinetic binding parameters of a monoclonal antibody.Q55479646
Quantitative recording of vitality patterns in living multicellular spheroids by confocal microscopy.Q55481264
Enhanced delivery of a monoclonal antibody F(ab')2 fragment to subcutaneous human glioma xenografts using local hyperthermia.Q55484637
Evaluation of an internal cyclotron target for the production of 211At via the 209Bi (α,2n)211At reactionQ56037984
Mathematical model of simultaneous diffusion and binding of antitumor antibodies in multicellular human tumor spheroidsQ64934173
Hyperthermia enhances localization of 111In-labeled hapten to bifunctional antibody in human colon tumor xenograftsQ68201773
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectastatineQ999
cytotoxicityQ246181
P304page(s)753-759
P577publication date1998-03-01
P1433published inBritish Journal of CancerQ326309
P1476titleCytotoxicity of alpha-particle-emitting astatine-211-labelled antibody in tumour spheroids: no effect of hyperthermia
P478volume77

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cites work (P2860)
Q33640550Astatine Radiopharmaceuticals: Prospects and Problems
Q52838956Automated cassette-based production of high specific activity [203/212Pb]peptide-based theranostic radiopharmaceuticals for image-guided radionuclide therapy for cancer.
Q36102652Cancer radioimmunotherapy with alpha-emitting nuclides
Q35184811Mild hyperthermia influence on Herceptin(®) properties.
Q49967540Targeted and Nontargeted α-Particle Therapies
Q40538520The role of heat shock protein 70 in the thermoresistance of prostate cancer cell line spheroids.
Q35692449Transcriptional Response in Mouse Thyroid Tissue after 211At Administration: Effects of Absorbed Dose, Initial Dose-Rate and Time after Administration

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