Ipilimumab (yervoy) prolongs survival in advanced melanoma: serious side effects and a hefty price tag may limit its use.

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Ipilimumab (yervoy) prolongs survival in advanced melanoma: serious side effects and a hefty price tag may limit its use. is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID3462607
P698PubMed publication ID23066344

P2093author name stringChris Fellner
P2860cites workCancer immunotherapy: moving beyond current vaccinesQ24548229
Improved Endpoints for Cancer Immunotherapy TrialsQ24603112
Ipilimumab: an anti-CTLA-4 antibody for metastatic melanomaQ27005902
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
Ipilimumab plus dacarbazine for previously untreated metastatic melanomaQ28131634
What is the role of cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma?Q28253687
Guidelines for the evaluation of immune therapy activity in solid tumors: immune-related response criteriaQ28265610
Final version of 2009 AJCC melanoma staging and classificationQ29614803
High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of 270 patients treated between 1985 and 1993Q29619885
Ipilimumab-induced thrombocytopenia in a patient with metastatic melanomaQ33396455
The heterogeneity of the kinetics of response to ipilimumab in metastatic melanoma: patient casesQ34111899
High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: long-term survival updateQ34507305
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging studyQ34614776
Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study.Q34616628
Clinical practice. Dysplastic neviQ35600912
Management of cutaneous melanomaQ35877006
Role of sun exposure in melanomaQ36471692
Immunostimulatory monoclonal antibodies for cancer therapyQ36717901
Temozolomide for the treatment of metastatic melanomaQ36852256
Targeting cytotoxic T-lymphocyte antigen-4 (CTLA-4): a novel strategy for the treatment of melanoma and other malignanciesQ37000638
Anti-cytotoxic T-lymphocyte antigen-4 antibody: the first in an emerging class of immunomodulatory antibodies for cancer treatmentQ37288227
Current systemic therapy for metastatic melanomaQ37483961
Ipilimumab: a novel treatment for metastatic melanomaQ37866936
Time and frequency of recurrence of cutaneous stage I malignant melanoma with guidelines for follow-up study.Q39711652
The CD4(+) T-cell response of melanoma patients to a MAGE-A3 peptide vaccine involves potential regulatory T cells.Q39852544
OPTIM trial: a Phase III trial of an oncolytic herpes virus encoding GM-CSF for unresectable stage III or IV melanomaQ39866378
A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanomaQ43293811
Hemophilia A induced by ipilimumabQ45874695
Phase I/II study of ipilimumab for patients with metastatic melanomaQ46087025
Ipilimumab.Q55054369
Latest developments in the treatment of melanoma: 'a penicillin moment for cancer'?Q55167727
A phase II multicenter study of ipilimumab with or without dacarbazine in chemotherapy-naïve patients with advanced melanomaQ56898845
Treating Cancer by Targeting the Immune SystemQ56899478
Dysplastic nevi. Markers for increased risk for melanomaQ69935984
Local and in-transit metastases following definitive excision for primary cutaneous malignant melanomaQ71758295
Identification of a new HLA-A(*)0201-restricted T-cell epitope from the tyrosinase-related protein 2 (TRP2) melanoma antigenQ74009023
Phase II study of direct intralesional gene transfer of allovectin-7, an HLA-B7/beta2-microglobulin DNA-liposome complex, in patients with metastatic melanomaQ74321019
Melanoma Vaccine--AVAX Technologies: DNP-VACC, M-VaxQ78814973
Factors predicting the risk of in-transit recurrence after sentinel lymphonodectomy in patients with cutaneous malignant melanomaQ79979019
Ipilimumab-induced sarcoidosis in a patient with metastatic melanoma undergoing complete remissionQ82713952
P433issue9
P921main subjectipilimumabQ2459042
P304page(s)503-530
P577publication date2012-09-01
P1433published inP & T: journal for formulary managementQ15767306
P1476titleIpilimumab (yervoy) prolongs survival in advanced melanoma: serious side effects and a hefty price tag may limit its use.
P478volume37

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cites work (P2860)
Q92377668A QSP Model for Predicting Clinical Responses to Monotherapy, Combination and Sequential Therapy Following CTLA-4, PD-1, and PD-L1 Checkpoint Blockade
Q39239484A review of the importance of immune responses in luminal B breast cancer.
Q87640700A survey of breakthrough therapy designations
Q37210896AACR Cancer Progress Report 2015
Q35104530Apical ballooning and cardiomyopathy in a melanoma patient treated with ipilimumab: a case of takotsubo-like syndrome
Q38837762Bending the Cost Curve in Childhood Cancer
Q92946963Cancer drug development: The missing links
Q88010589Combination immunotherapies implementing adoptive T-cell transfer for advanced-stage melanoma
Q47882190Combination ipilimumab and radiosurgery for brain metastases: tumor, edema, and adverse radiation effects
Q92026257Comparative Radioimmunotherapy of Experimental Melanoma with Novel Humanized Antibody to Melanin Labeled with 213Bismuth and 177Lutetium
Q92317540Current state of melanoma diagnosis and treatment
Q37437556Dynamic contrast-enhanced MRI coupled with a subtraction technique is useful for treatment response evaluation of malignant melanoma hepatic metastasis
Q26744527Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune Response
Q26829997Emerging targeted therapies for melanoma treatment (review)
Q34524746First-in-human phase I study of the DNA-repair inhibitor DT01 in combination with radiotherapy in patients with skin metastases from melanoma
Q38908076Growth inhibitory activity of Ankaferd hemostat on primary melanoma cells and cell lines
Q38392912Immune biomarkers: the promises and pitfalls of personalized medicine.
Q57483931Immune-checkpoint inhibitors for combating T-cell dysfunction in cancer
Q37393253Incidence of Thyroid-Related Adverse Events in Melanoma Patients Treated With Pembrolizumab
Q45904325Ipilimumab treatment results in an early decrease in the frequency of circulating granulocytic myeloid derived suppressor cells as well as their arginase1 production.
Q39627433Late onset ipilimumab-induced pericarditis and pericardial effusion: a rare but life threatening complication
Q51071853Metastatic Melanoma: Treatment and Survival in the US after the Introduction of Ipilimumab and Vemurafenib.
Q88060558Nanoparticle Design Strategies for Effective Cancer Immunotherapy
Q28081774Overcoming tumor immune evasion with an unique arbovirus
Q28067141PD-1 Pathway Inhibitors: Immuno-Oncology Agents for Restoring Antitumor Immune Responses
Q28076905PLGA-loaded nanomedicines in melanoma treatment: Future prospect for efficient drug delivery
Q55352057Personalized Medicine in Malignant Melanoma: Towards Patient Tailored Treatment.
Q60652342Predictive value of early 18F-FDG PET/CT studies for treatment response evaluation to ipilimumab in metastatic melanoma: preliminary results of an ongoing study
Q52608848Structure-function analysis and therapeutic efficacy of antibodies to fungal melanin for melanoma radioimmunotherapy.
Q38831830Targeting immune checkpoints in unresectable metastatic cutaneous melanoma: a systematic review and meta-analysis of anti-CTLA-4 and anti-PD-1 agents trials
Q33946513Targeting the PD-1 pathway: a promising future for the treatment of melanoma.
Q57148977The Current Status and Future Prospects of Oncolytic Viruses in Clinical Trials against Melanoma, Glioma, Pancreatic, and Breast Cancers
Q36771571The MAPK (ERK) Pathway: Investigational Combinations for the Treatment Of BRAF-Mutated Metastatic Melanoma
Q59128386The Role of Melanoma Cell-Stroma Interaction in Cell Motility, Invasion, and Metastasis
Q64256609The Tolerogenic Function of Regulatory T Cells in Pregnancy and Cancer
Q33634914Treatment patterns in patients with metastatic melanoma: a retrospective analysis
Q38730989Tumor immunotherapy: drug-induced neoantigens (xenogenization) and immune checkpoint inhibitors
Q27014693Update on the challenges and recent advances in cancer immunotherapy
Q53641696What's fueling the biotech engine-2012 to 2013.
Q98613558Why natural killer cells in triple negative breast cancer?