Selection, Characterization and Application of Artificial DNA Aptamer Containing Appended Bases with Sub-nanomolar Affinity for a Salivary Biomarker.

scientific article

Selection, Characterization and Application of Artificial DNA Aptamer Containing Appended Bases with Sub-nanomolar Affinity for a Salivary Biomarker. is …
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scholarly articleQ13442814

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P356DOI10.1038/SREP42716
P932PMC publication ID5335659
P698PubMed publication ID28256555

P50authorIkuo ShiratoriQ58669446
P2093author name stringKatsunori Horii
Iwao Waga
Masayasu Kuwahara
Hiroto Fujita
Taiichi Sakamoto
Joe Akitomi
Naoto Kaneko
Hirotaka Minagawa
Kentaro Onodera
P2860cites workGeneration of high-affinity DNA aptamers using an expanded genetic alphabetQ22122129
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Aptamer-based multiplexed proteomic technology for biomarker discoveryQ28744329
Bridging the gap between proteins and nucleic acids: a metal-independent RNAseA mimic with two protein-like functionalitiesQ30689114
Aptamer-functionalized gold nanoparticles as probes in a dry-reagent strip biosensor for protein analysisQ43484075
Novel One-Tube-One-Step Real-Time Methodology for Rapid Transcriptomic Biomarker Detection: Signal Amplification by Ternary Initiation Complexes.Q53072880
Chemico-enzymatic synthesis of a new fluorescent-labeled DNA by PCR with a thymidine nucleotide analogue bearing an acridone derivative.Q54572287
Polymerase-mediated high-density incorporation of amphiphilic functionalities into DNA: enhancement of nuclease resistance and stability in human serum.Q55069516
A disposable biosensor for the determination of alpha-amylase in human salivaQ57840239
[Biomarkers of stress and fatigue]Q83818180
Antibody-specific aptamer-based PCR analysis for sensitive protein detectionQ84460989
Live Cell MicroRNA Imaging Using Cascade Hybridization ReactionQ87226935
Quantitative analysis of receptors for adenosine nucleotides obtained via in vitro selection from a library incorporating a cationic nucleotide analogQ30711730
A novel, modification-dependent ATP-binding aptamer selected from an RNA library incorporating a cationic functionalityQ30966817
Sialyllactose-binding modified DNA aptamer bearing additional functionality by SELEX.Q33198575
Modified DNA aptamer that binds the (R)-isomer of a thalidomide derivative with high enantioselectivityQ33270917
Expanding the chemistry of DNA for in vitro selectionQ33536734
Designing anti-influenza aptamers: novel quantitative structure activity relationship approach gives insights into aptamer-virus interactionQ33638356
Synthetic genetic polymers capable of heredity and evolutionQ34031569
Developmental validation of a point-of-care, salivary α-amylase biosensorQ34376265
Challenging artificial genetic systems: thymidine analogs with 5-position sulfur functionalityQ34376741
Artificial specific binders directly recovered from chemically modified nucleic acid librariesQ34456694
2',4'-BNA/LNA aptamers: CE-SELEX using a DNA-based library of full-length 2'-O,4'-C-methylene-bridged/linked bicyclic ribonucleotidesQ34572297
Capillary electrophoresis-systematic evolution of ligands by exponential enrichment selection of base- and sugar-modified DNA aptamers: target binding dominated by 2'-O,4'-C-methylene-bridged/locked nucleic acid primerQ34714314
Efficacy of base-modification on target binding of small molecule DNA aptamersQ34756361
In vitro selection of DNA-based aptamers that exhibit RNA-like conformations using a chimeric oligonucleotide library that contains two different xeno-nucleic acidsQ35343698
A Nonenzymatic Hairpin DNA Cascade Reaction Provides High Signal Gain of mRNA Imaging inside Live CellsQ35596347
Psychosocial Stress Increases Salivary Alpha-Amylase Activity Independently from Plasma Noradrenaline LevelsQ35738769
Assembly of aptamer switch probes and photosensitizer on gold nanorods for targeted photothermal and photodynamic cancer therapyQ36124916
In vitro evolution of chemically-modified nucleic acid aptamers: Pros and cons, and comprehensive selection strategiesQ36156320
Selection of 2'-deoxy-2'-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinityQ36575322
The application of a modified nucleotide in aptamer selection: novel thrombin aptamers containing 5-(1-pentynyl)-2'-deoxyuridineQ36675591
Rolling circle amplification: applications in nanotechnology and biodetection with functional nucleic acidsQ37235208
Molecular evolution of functional nucleic acids with chemical modificationsQ37780443
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Is salivary alpha-amylase an indicator of autonomic nervous system dysregulations in mental disorders?--a review of preliminary findings and the interactions with cortisolQ38088495
Aptamer switch probe based on intramolecular displacementQ38288570
Programmable DNA scaffolds for spatially-ordered protein assemblyQ38293960
Arginine-modified DNA aptamers that show enantioselective recognition of the dicarboxylic acid moiety of glutamic acidQ38294670
Selection of DNA aptamers that bind to influenza A viruses with high affinity and broad subtype specificity.Q38310980
Application of microchip electrophoresis in the analysis of RNA aptamer-protein interactionsQ38311537
Detection of Clostridium difficile toxins A, B and binary toxin with slow off-rate modified aptamersQ38315427
High-throughput quantitative screening of peroxidase-mimicking DNAzymes on a microarray by using electrochemical detectionQ38316015
Systematic characterization of 2'-deoxynucleoside- 5'-triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies on enzymatic production of modified DNAQ39117143
Influence of 5-N-carboxamide modifications on the thermodynamic stability of oligonucleotides.Q40464660
Estimation of salivary amylase in diabetic patients and saliva as a diagnostic tool in early diabetic patientsQ41848861
Development of a Sphingosylphosphorylcholine Detection System Using RNA AptamersQ42929923
Aptamer-DNAzyme hairpins for amplified biosensingQ43271457
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectbiomarkerQ864574
P304page(s)42716
P577publication date2017-03-03
P1433published inScientific ReportsQ2261792
P1476titleSelection, Characterization and Application of Artificial DNA Aptamer Containing Appended Bases with Sub-nanomolar Affinity for a Salivary Biomarker
P478volume7

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cites work (P2860)
Q92894930Capillary electrophoresis-based immunoassay and aptamer assay: A review
Q41573492Chemical Modifications of Nucleic Acid Aptamers for Therapeutic Purposes.
Q47104247Nucleic Acid Aptamers: Emerging Applications in Medical Imaging, Nanotechnology, Neurosciences, and Drug Delivery.
Q47363650Specific Light-Up System for Protein and Metabolite Targets Triggered by Initiation Complex Formation.
Q99241275Structure and Elastic Properties of an Unsymmetrical Bi-Heterocyclic Azo Compound in the Langmuir Monolayer and Langmuir-Blodgett Film

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