Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction (scientific article)

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines

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Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis

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Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata

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The inflammatory response in myocardial injury, repair, and remodelling.

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Therapeutic siRNA silencing in inflammatory monocytes in mice

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Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells

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Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis

Q35679591

Extramedullary hematopoiesis generates Ly-6C(high) monocytes that infiltrate atherosclerotic lesions

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Division-coupled astrocytic differentiation and age-related depletion of neural stem cells in the adult hippocampus

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The bone marrow niche for haematopoietic stem cells

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Myocardial infarction accelerates atherosclerosis.

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Investigation of the effect of Interleukin-1 receptor antagonist (IL-1ra) on markers of inflammation in non-ST elevation acute coronary syndromes (The MRC-ILA-HEART Study).

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Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling.

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Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

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Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study].

Q36816882

Uncertainty in the niches that maintain haematopoietic stem cells

Q37103620

Monocyte and macrophage heterogeneity in the heart

Q37122225

IL-1 induces proinflammatory leukocyte infiltration and regulates fibroblast phenotype in the infarcted myocardium.

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The role of IL-1 in the pathogenesis of heart disease.

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The IL-1 family: regulators of immunity

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Monocyte and macrophage dynamics during atherogenesis

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Mechanisms of acute coronary syndromes and their implications for therapy

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Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis.

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ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation

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Macrophages are required for neonatal heart regeneration

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IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia

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Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity

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IFNalpha activates dormant haematopoietic stem cells in vivo.

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Neural stem and progenitor cells in nestin-GFP transgenic mice

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Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse

Q44955371

Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study).

Q44956453

Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct.

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Cytokine signaling during myocardial infarction: sequential appearance of IL-1 beta and IL-6

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Neutralization of interleukin-1 beta activity in vivo with a monoclonal antibody alleviates collagen-induced arthritis in DBA/1 mice and prevents the associated acute-phase response

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Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice

Q74171931

Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats

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Monoclonal antibodies targeting IL-1 beta reduce biomarkers of atherosclerosis in vitro and inhibit atherosclerotic plaque formation in Apolipoprotein E-deficient mice

Q83630548

Interleukin-1β inhibition and the prevention of recurrent cardiovascular events: rationale and design of the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

Q85063666

IL-1 signaling in atherosclerosis: sibling rivalry

Q85947638

SnapShot: The hematopoietic stem cell niche

Q88219347

P433

issue

P407

language of work or name

English

Q1860

P921

main subject

myocardial infarction

Q12152

interleukins

Q194908

acute myocardial infarction

Q18558122

P304

page(s)

1880-1890

P577

publication date

2015-09-10

P1433

published in

Circulation

Q578091

P1476

title

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction

P478

volume

132

Reverse relations

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P356	DOI	10.1161/CIRCULATIONAHA.115.016160
P932	PMC publication ID	4651795
P698	PubMed publication ID	26358260