Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage display

scientific article published on October 2, 2012

Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage display is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/CB300339P
P953full work available online athttps://doi.org/10.1021/cb300339p
https://europepmc.org/articles/PMC4652587
https://europepmc.org/articles/pmc4652587?pdf=render
https://europepmc.org/articles/PMC4652587?pdf=render
P932PMC publication ID4652587
P698PubMed publication ID23003343

P50authorHermann SchindelinQ89492297
P2093author name stringBo Zhao
Jun Yin
Karan Bhuripanyo
Keya Zhang
Jeffrey Schneider
David Boone
P2860cites workA MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2Q22009372
E1-L2 activates both ubiquitin and FAT10Q24294748
The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2Q24294888
Active site remodelling accompanies thioester bond formation in the SUMO E1Q24299970
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybridsQ24300880
Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathwaysQ24647626
Atypical ubiquitin chains: new molecular signals. 'Protein Modifications: Beyond the Usual Suspects' review seriesQ24655287
Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tailQ27635260
Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymesQ27651368
The structure of the UbcH8-ubiquitin complex shows a unique ubiquitin interaction siteQ27658283
Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L ComplexQ27658921
Crystal structure of UbcH5b~ubiquitin intermediate: insight into the formation of the self-assembled E2~Ub conjugatesQ27659805
Modulation of K11-linkage formation by variable loop residues within UbcH5AQ27666943
Mechanism of ubiquitylation by dimeric RING ligase RNF4Q27671855
Structural Insights into the Conformation and Oligomerization of E2∼Ubiquitin ConjugatesQ27678872
RING domain E3 ubiquitin ligasesQ27860546
Mechanisms underlying ubiquitinationQ27860656
The ubiquitin systemQ27860803
Functional domains of the Rsp5 ubiquitin-protein ligase.Q27931992
The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitinQ27939113
Breaking the chains: structure and function of the deubiquitinasesQ28131738
CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylationQ28216253
The mechanism of ubiquitin activating enzyme. A kinetic and equilibrium analysisQ28264747
E2s: structurally economical and functionally repleteQ28301074
Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme chargingQ28307753
Essential Role for Ubiquitin-Ubiquitin-Conjugating Enzyme Interaction in Ubiquitin Discharge from Cdc34 to SubstrateQ28740322
Nonproteolytic functions of ubiquitin in cell signalingQ29617294
Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formationQ29619698
Ubiquitin and ubiquitin-like proteins as multifunctional signalsQ30014838
Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes).Q33349184
Orthogonal Ubiquitin Transfer through Engineered E1-E2 Cascades for Protein UbiquitinationQ33924565
Characterization of the novel E3 ubiquitin ligase encoded in exon 3 of herpes simplex virus-1-infected cell protein 0.Q34030278
Ubiquitin-activating enzyme. Mechanism and role in protein-ubiquitin conjugationQ34055195
Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzymeQ34595903
Activation of the heat-stable polypeptide of the ATP-dependent proteolytic systemQ35414574
Mechanistic Studies on Activation of Ubiquitin and Di-ubiquitin-like Protein, FAT10, by Ubiquitin-like Modifier Activating Enzyme 6, Uba6Q35939802
Stimulation of ATP-dependent proteolysis requires ubiquitin with the COOH-terminal sequence Arg-Gly-GlyQ39341884
Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitroQ39686108
Functional characterization of the ubiquitin variant encoded by the baculovirus Autographa californicaQ43566066
Distinct functional surface regions on ubiquitinQ43635274
Ubiquitin function studied by disulfide engineeringQ48305732
Gene synthesis, expression, structures, and functional activities of site-specific mutants of ubiquitinQ48336933
Folding and stability of a tryptophan-containing mutant of ubiquitinQ50781198
Structure and function of ubiquitin: evidence for differential interactions of arginine-74 with the activating enzyme and the proteases of ATP-dependent proteolysisQ69815938
The inactivation of ubiquitin accounts for the inability to demonstrate ATP, ubiquitin-dependent proteolysis in liver extractsQ70083060
Ubiquitin adenylate: structure and role in ubiquitin activationQ70168206
Site-directed mutagenesis of ubiquitin. Differential roles for arginine in the interaction with ubiquitin-activating enzymeQ71994577
Substrate properties of site-specific mutant ubiquitin protein (G76A) reveal unexpected mechanistic features of ubiquitin-activating enzyme (E1)Q72287606
Substrate recognition and catalysis by UCH-L1Q79403462
Ubiquitin transfer from the E2 perspective: why is UbcH5 so promiscuous?Q79546828
Site-specific protein labeling by Sfp phosphopantetheinyl transferaseQ80092828
A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitinationQ82857335
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectphage displayQ896217
P304page(s)2027-2035
P577publication date2012-10-02
P1433published inACS Chemical BiologyQ165583
P1476titleSpecificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage display
P478volume7

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cites work (P2860)
Q41643543An affinity-directed protein missile system for targeted proteolysis.
Q27026146Applied techniques for mining natural proteasome inhibitors
Q39065396DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells
Q36298696Inhibiting the Protein Ubiquitination Cascade by Ubiquitin-Mimicking Short Peptides
Q49379923MicroRNA‑32 silences WWP2 expression to maintain the pluripotency of human amniotic epithelial stem cells and β islet‑like cell differentiation
Q34793372Phage Display to Identify Nedd8‐Mimicking Peptides as Inhibitors of the Nedd8 Transfer Cascade
Q35538302Phage selection assisted by Sfp phosphopantetheinyl transferase-catalyzed site-specific protein labeling
Q34925373Profiling the cross reactivity of ubiquitin with the Nedd8 activating enzyme by phage display
Q89925905Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond
Q35440501SUMO-mimicking peptides inhibiting protein SUMOylation
Q40336938Structure of UBE2Z Enzyme Provides Functional Insight into Specificity in the FAT10 Protein Conjugation Machinery
Q36291108Synthesis and screening of peptide libraries with free C-termini
Q30584192Systematic exploration of ubiquitin sequence, E1 activation efficiency, and experimental fitness in yeast
Q91671236Ubiquitin-Mimicking Peptides Transfer Differentiates by E1 and E2 Enzymes

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