Negative charges at protein kinase C sites of troponin I stabilize the inactive state of actin

scientific article

Negative charges at protein kinase C sites of troponin I stabilize the inactive state of actin is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1529/BIOPHYSJ.107.113944
P932PMC publication ID2157249
P698PubMed publication ID17872964
P5875ResearchGate publication ID5969831

P2093author name stringTomoyoshi Kobayashi
Joseph M Chalovich
Mohit C Mathur
P2860cites workStructure of the core domain of human cardiac troponin in the Ca(2+)-saturated formQ24306847
Protein kinase cascades in the regulation of cardiac hypertrophyQ24518494
NMR solution structure of calcium-saturated skeletal muscle troponin CQ27732189
Phosphorylation or glutamic acid substitution at protein kinase C sites on cardiac troponin I differentially depress myofilament tension and shortening velocityQ28205242
Calcium, thin filaments, and the integrative biology of cardiac contractilityQ28234995
Ca(2+)-regulated structural changes in troponinQ28241337
What is the role of tropomyosin in the regulation of muscle contraction?Q28243862
Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filamentQ28255352
Phosphorylation specificities of protein kinase C isozymes for bovine cardiac troponin I and troponin T and sites within these proteins and regulation of myofilament propertiesQ28289247
Cardiac troponin I mutants. Phosphorylation by protein kinases C and A and regulation of Ca(2+)-stimulated MgATPase of reconstituted actomyosin S-1Q28291787
A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase CQ28300371
Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile responseQ28569756
Regulation of contraction in striated muscleQ28610114
Effects of a cardiomyopathy-causing troponin t mutation on thin filament function and structure.Q30328020
Troponin: structure, properties, and mechanism of functioningQ33751882
Inhibition of actomyosin ATPase activity by troponin-tropomyosin without blocking the binding of myosin to actin.Q34099114
Cooperative regulation of myosin-actin interactions by a continuous flexible chain II: actin-tropomyosin-troponin and regulation by calcium.Q34181121
Ca2+ and ionic strength dependencies of S1-ADP binding to actin-tropomyosin-troponin: regulatory implications.Q34187090
Theoretical models for cooperative steady-state ATPase activity of myosin subfragment-1 on regulated actinQ34252297
Mechanism of action of troponin . tropomyosin. Inhibition of actomyosin ATPase activity without inhibition of myosin binding to actinQ34312813
Mechanism of regulation of phosphate dissociation from actomyosin-ADP-Pi by thin filament proteinsQ34429702
Activation mechanisms of protein kinase C: maturation, catalytic activation, and targetingQ34989325
Regulation of striated muscle contraction: a discussionQ35083419
Actin mediated regulation of muscle contractionQ35191890
Protein kinase C isoform-selective signals that lead to cardiac hypertrophy and the progression of heart failureQ35566719
Theoretical model for the cooperative equilibrium binding of myosin subfragment 1 to the actin-troponin-tropomyosin complexQ36392077
Separation of subfragment-1 isoenzymes from rabbit skeletal muscle myosinQ39741645
Anchoring proteins for protein kinase C: a means for isozyme selectivityQ41686822
The Delta 14 mutation of human cardiac troponin T enhances ATPase activity and alters the cooperative binding of S1-ADP to regulated actin.Q42185032
The mechanism of regulation of actomyosin subfragment 1 ATPaseQ42204016
Mutations in human cardiac troponin I that are associated with restrictive cardiomyopathy affect basal ATPase activity and the calcium sensitivity of force developmentQ42479969
Troponin I serines 43/45 and regulation of cardiac myofilament functionQ42524860
alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI.Q43988635
Maximal activation of skeletal muscle thin filaments requires both rigor myosin S1 and calciumQ46722180
A new look at thin filament regulation in vertebrate skeletal muscle.Q47870864
Quantitative dynamics of site-specific protein phosphorylation determined using liquid chromatography electrospray ionization mass spectrometry.Q50500006
Studies on co-operative properties of tropomyosin-actin and tropomyosin-troponin-actin complexes by the use of N-ethylmaleimide-treated and untreated species of myosin subfragment 1.Q52723619
Structure of the calcium regulatory muscle protein troponin-C at 2.8 Å resolutionQ60914236
Reconstitution of troponin activity from three protein componentsQ68475059
Cooperative turning on of myosin subfragment 1 adenosinetriphosphatase activity by the troponin-tropomyosin-actin complexQ70065317
Role of intracellular Ca2+ in activation of protein kinase C during ischemic preconditioningQ73673877
A new model of cooperative myosin-thin filament bindingQ73919625
A model for the myosin moleculeQ78794593
PKC-betaII sensitizes cardiac myofilaments to Ca2+ by phosphorylating troponin I on threonine-144Q79162724
Some precautions in using chelators to buffer metals in biological solutionsQ79740748
Introduction of negative charge mimicking protein kinase C phosphorylation of cardiac troponin I. Effects on cardiac troponin CQ80865642
Increased Ca2+ affinity of cardiac thin filaments reconstituted with cardiomyopathy-related mutant cardiac troponin IQ82796150
P433issue2
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)542-549
P577publication date2007-09-14
P1433published inBiophysical JournalQ2032955
P1476titleNegative charges at protein kinase C sites of troponin I stabilize the inactive state of actin
P478volume94