Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma

scientific article

Autophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M112.370585
P932PMC publication ID3471698
P698PubMed publication ID22927446

P2093author name stringYan Chen
Ke Gong
Chao Chen
Wenhua Li
Zebo Huang
Yao Zhan
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Hepatocellular carcinomaQ29615841
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Bnip3 mediates permeabilization of mitochondria and release of cytochrome c via a novel mechanismQ33838261
Tetrandrine induces apoptosis by activating reactive oxygen species and repressing Akt activity in human hepatocellular carcinomaQ34024893
Histone deacetylase inhibitors in cancer therapyQ73209407
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Gossypol induces death receptor-5 through activation of the ROS-ERK-CHOP pathway and sensitizes colon cancer cells to TRAILQ34285051
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p38α mediates cell survival in response to oxidative stress via induction of antioxidant genes: effect on the p70S6K pathwayQ35710005
Autophagy as a cell death and tumor suppressor mechanismQ35743138
The role of autophagy in cancer development and response to therapy.Q36251939
Methods for the assessment of mitochondrial membrane permeabilization in apoptosisQ36733683
The permeability transition pore in cell deathQ36799163
Neuronal autophagy: going the distance to the axon.Q37174272
Cell death and autophagy: cytokines, drugs, and nutritional factorsQ37241355
Apoptosis and non-apoptotic deaths in cancer development and treatment responseQ37250355
Apoptosis and human diseases: mitochondrion damage and lethal role of released cytochrome C as proapoptotic proteinQ37597328
Apoptosis and autophagy: Regulation of caspase-9 by phosphorylation.Q37605158
Macroautophagy and its role in nutrient homeostasisQ37639473
Autophagy in nuclear receptor PPARgamma-deficient mouse prostatic carcinogenesisQ37653920
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Mitochondrial ROS generation for regulation of autophagic pathways in cancerQ37939467
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β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activationQ39472593
Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.Q39505782
Combination of arsenic trioxide and BCNU synergistically triggers redox-mediated autophagic cell death in human solid tumorsQ39697126
Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathwayQ39770153
RNAi-mediated MEK1 knock-down prevents ERK1/2 activation and abolishes human hepatocarcinoma growth in vitro and in vivoQ39789497
Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell linesQ39819940
Tetrandrine induces apoptosis and growth suppression of colon cancer cells in miceQ39827452
Superoxide is the major reactive oxygen species regulating autophagyQ39858156
Tetrandrine suppresses tumor growth and angiogenesis of gliomas in ratsQ39891555
Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.Q40192837
Reactive oxygen species and programmed cell deathQ41178312
Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availabilityQ41962450
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagyQ42058524
Reactive oxygen species mediate cyclic strain-induced endothelin-1 gene expression via Ras/Raf/extracellular signal-regulated kinase pathway in endothelial cellsQ43768605
Anti-inflammatory effects of the partially purified extract of radix Stephaniae tetrandrae: comparative studies of its active principles tetrandrine and fangchinoline on human polymorphonuclear leukocyte functionsQ43771515
Tetrandrine-induced cell cycle arrest and apoptosis in A549 human lung carcinoma cells.Q44215132
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinomaQ44845088
Tetrandrine-induced apoptosis is mediated by activation of caspases and PKC-delta in U937 cellsQ44886334
Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector.Q45864831
Tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkappaBalpha-NF-kappaB signaling pathwayQ46580609
The Rac activator Tiam1 prevents keratinocyte apoptosis by controlling ROS-mediated ERK phosphorylationQ46694931
Cytotoxicity to macrophages of tetrandrine, an antisilicosis alkaloid, accompanied by an overproduction of prostaglandinsQ46928180
Elevated levels of IL-1beta in Fanconi anaemia group A patients due to a constitutively active phosphoinositide 3-kinase-Akt pathway are capable of promoting tumour cell proliferationQ47717772
Tissue-specific Autophagy Alterations and Increased Tumorigenesis in Mice Deficient in Atg4C/Autophagin-3Q56777123
P433issue42
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
reactive oxygen speciesQ424361
P1104number of pages13
P304page(s)35576-35588
P577publication date2012-08-27
P1433published inJournal of Biological ChemistryQ867727
P1476titleAutophagy-related gene 7 (ATG7) and reactive oxygen species/extracellular signal-regulated kinase regulate tetrandrine-induced autophagy in human hepatocellular carcinoma
P478volume287

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