Development of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection

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Development of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0173509
P932PMC publication ID5363796
P698PubMed publication ID28334018

P50authorKay SedenQ82805885
P2093author name stringDavid M Burger
Sara Gibbons
Saye H Khoo
Catia Marzolini
Jonathan M Schapiro
David J Back
P2860cites workCYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquineQ21034109
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GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tablesQ29547885
HIV-positive nigerian adults harbor significantly higher serum lumefantrine levels than HIV-negative individuals seven days after treatment for Plasmodium falciparum infectionQ30392186
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Pharmacokinetic interactions between ritonavir and quinine in healthy volunteers following concurrent administrationQ33692808
Glucuronidation of 3'-azido-3'-deoxythymidine (zidovudine) by human liver microsomes: relevance to clinical pharmacokinetic interactions with atovaquone, fluconazole, methadone, and valproic acidQ33693946
Outcome of artemether-lumefantrine treatment for uncomplicated malaria in HIV-infected adult patients on anti-retroviral therapyQ33733033
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Artemisinin-based combination therapies are efficacious and safe for treatment of uncomplicated malaria in HIV-infected Ugandan childrenQ34137766
Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activityQ34233691
In vitro inhibition of UDP glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidationQ34445138
Use of a physiologically-based pharmacokinetic model to simulate artemether dose adjustment for overcoming the drug-drug interaction with efavirenz.Q34503553
Efavirenz Inhibits the Human Ether-A-Go-Go Related Current (hERG) and Induces QT Interval Prolongation in CYP2B6*6*6 Allele CarriersQ34531724
Marked increase in etravirine and saquinavir plasma concentrations during atovaquone/proguanil prophylaxisQ35038647
Artemether-lumefantrine co-administration with antiretrovirals: population pharmacokinetics and dosing implicationsQ35286119
The influence of nevirapine and efavirenz-based anti-retroviral therapy on the pharmacokinetics of lumefantrine and anti-malarial dose recommendation in HIV-malaria co-treatmentQ35583982
Interaction between artemether-lumefantrine and nevirapine-based antiretroviral therapy in HIV-1-infected patients.Q35598594
Cardiac Conduction Safety during Coadministration of Artemether-Lumefantrine and Lopinavir/Ritonavir in HIV-Infected Ugandan AdultsQ35692134
Drug-drug interaction analysis of pyronaridine/artesunate and ritonavir in healthy volunteersQ35771822
Zidovudine side effects as reported by black, Hispanic, and white/non-Hispanic patients with early HIV disease: combined analysis of two multicenter placebo-controlled trialsQ46327747
Atovaquone inhibits the glucuronidation and increases the plasma concentrations of zidovudineQ46691027
No drug-drug interaction between nelfinavir or indinavir and mefloquine in HIV-1-infected patientsQ47875301
Effects of ritonavir-boosted lopinavir on the pharmacokinetics of quinineQ48006398
Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteersQ48705073
Hepatotoxicity Due to a Drug Interaction between Amodiaquine plus Artesunate and EfavirenzQ56833699
Recognition of Risk for Clinically Significant Drug Interactions among HIV‐Infected Patients Receiving Antiretroviral TherapyQ58858328
Nevirapine-Based Antiretroviral Therapy Impacts Artesunate and Dihydroartemisinin Disposition in HIV-Infected Nigerian AdultsQ35829744
Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adultsQ35883504
The interaction between artemether-lumefantrine and lopinavir/ritonavir-based antiretroviral therapy in HIV-1 infected patientsQ35906361
Pharmacokinetic interactions between artesunate-mefloquine and ritonavir-boosted lopinavir in healthy Thai adultsQ36144257
Artemether-Lumefantrine Exposure in HIV-Infected Nigerian Subjects on Nevirapine-Containing Antiretroviral TherapyQ36290691
Prevalence and type of drug-drug interactions involving ART in patients attending a specialist HIV outpatient clinic in Kampala, UgandaQ36298965
Significant pharmacokinetic interactions between artemether/lumefantrine and efavirenz or nevirapine in HIV-infected Ugandan adultsQ36300127
Pharmacokinetic Interactions Between Quinine and Lopinavir/Ritonavir in Healthy Thai AdultsQ36359372
Concomitant efavirenz reduces pharmacokinetic exposure to the antimalarial drug artemether-lumefantrine in healthy volunteersQ36438820
Antiretroviral medication errors among hospitalized patients with HIV infectionQ36581552
Effect of malaria on HIV/AIDS transmission and progressionQ36588773
Efavirenz but Not Atazanavir/Ritonavir Significantly Reduces Atovaquone Concentrations in HIV-Infected SubjectsQ36715824
Epidemiology and burden of malaria in pregnancyQ36717617
Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan childrenQ36739784
Antiretroviral agents and prevention of malaria in HIV-infected Ugandan childrenQ36876420
Prevalence and risk factors for clinically significant drug interactions with antiretroviral therapyQ36951993
Effects of concurrent administration of nevirapine on the disposition of quinine in healthy volunteersQ37364219
Preliminary study of quinine pharmacokinetics in pregnant women with malaria-HIV co-infectionQ37623297
Disposition of amodiaquine and desethylamodiaquine in HIV-infected Nigerian subjects on nevirapine-containing antiretroviral therapyQ37688260
Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapyQ37811962
High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in UgandaQ38876341
Proguanil disposition and toxicity in malaria patients from Vanuatu with high frequencies of CYP2C19 mutationsQ39119074
Population pharmacokinetics of mefloquine in patients with acute falciparum malariaQ39465442
Malaria therapy in HIV: drug interactions between nevirapine and quinineQ39544185
Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamineQ39753519
Lopinavir/ritonavir affects pharmacokinetic exposure of artemether/lumefantrine in HIV-uninfected healthy volunteersQ39972769
CYP2B6*6 genotype and high efavirenz plasma concentration but not nevirapine are associated with low lumefantrine plasma exposure and poor treatment response in HIV-malaria-coinfected patientsQ41240864
Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implicationsQ41292997
Lack of effect of doxycycline on trough concentrations of protease inhibitors or non-nucleoside reverse transcriptase inhibitors in HIV-infected patients.Q42249419
Lower atovaquone/proguanil concentrations in patients taking efavirenz, lopinavir/ritonavir or atazanavir/ritonavirQ43124514
Alteration of pharmacokinetics of proguanil in healthy volunteers following concurrent administration of efavirenzQ43229568
Pharmacokinetic interaction between etravirine or darunavir/ritonavir and artemether/lumefantrine in healthy volunteers: a two-panel, two-way, two-period, randomized trialQ43418234
Evaluation of clinical pharmacist interventions on drug interactions in outpatient pharmaceutical HIV-careQ43488729
Comparative pharmacokinetics and effect kinetics of orally administered artesunate in healthy volunteers and patients with uncomplicated falciparum malariaQ43855077
Prevalence of comedications and effect of potential drug-drug interactions in the Swiss HIV Cohort StudyQ43867180
Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in AfricaQ43932822
Function and mechanism of pyronaridine: a new inhibitor of P-glycoprotein-mediated multidrug resistanceQ44024752
The clinical utility of HIV outpatient pharmacist prescreening to reduce medication error and assess adherence.Q44273051
In vitro metabolism of clindamycin in human liver and intestinal microsomesQ44483232
Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.Q45925838
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
drug interactionQ718753
P304page(s)e0173509
P577publication date2017-03-23
P1433published inPLOS OneQ564954
P1476titleDevelopment of an evidence evaluation and synthesis system for drug-drug interactions, and its application to a systematic review of HIV and malaria co-infection
P478volume12

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cites work (P2860)
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Q91438525Contemporary Drug-Drug Interactions in HIV Treatment
Q64939082Drug-Drug Interactions of Infectious Disease Treatments in Low-Income Countries: A Neglected Topic?
Q54208950Effect of antiretroviral therapy on plasma concentrations of chloroquine and desethyl-chloroquine.
Q64285007Efficacy and safety of artemether-lumefantrine as treatment for Plasmodium falciparum uncomplicated malaria in adult patients on efavirenz-based antiretroviral therapy in Zambia: an open label non-randomized interventional trial
Q92723500Efficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium falciparum uncomplicated malaria in adult patients on antiretroviral therapy in Malawi and Mozambique: an open label non-randomized interventional trial
Q40133890The application of physiologically-based pharmacokinetic modelling to assess the impact of antiretroviral-mediated drug-drug interactions on piperaquine antimalarial therapy during pregnancy