Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration

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Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200409049
P932PMC publication ID2171584
P698PubMed publication ID15657395
P5875ResearchGate publication ID40713172

P50authorMichael F. OlsonQ39631766
Mathew L ColemanQ54087311
P2093author name stringDavid Robertson
Shuixing Li
Colin L Stewart
Teresa Sullivan
Daniel R Croft
P2860cites workRho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loopQ22011174
Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junctionQ22254386
Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinaseQ24290361
Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissuesQ24292172
Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/CQ24292190
NUANCE, a giant protein connecting the nucleus and actin cytoskeletonQ24301510
Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitroQ24303760
The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300Q24314644
LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505Q24532377
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue KineticsQ24564912
The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeletonQ24648481
Loss of A-type lamin expression compromises nuclear envelope integrity leading to muscular dystrophyQ24681029
Lamin proteolysis facilitates nuclear events during apoptosisQ24681695
Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membraneQ24683879
Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphataseQ28140582
Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbingQ28210013
Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cellsQ28213954
Cytoplasmic dynein as a facilitator of nuclear envelope breakdownQ28215594
Life at the edge: the nuclear envelope and human diseaseQ28216767
Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosisQ28286361
Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesisQ28298687
3T3 cells have nuclear invaginations containing F-actinQ33178057
ANChors away: an actin based mechanism of nuclear positioningQ33185450
Autoantigens as substrates for apoptotic proteases: implications for the pathogenesis of systemic autoimmune diseaseQ33592314
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.Q33941102
Swinholide A is a microfilament disrupting marine toxin that stabilizes actin dimers and severs actin filamentsQ34319852
Rho GTPase signalling pathways in the morphological changes associated with apoptosis.Q34612747
Role of ANC-1 in tethering nuclei to the actin cytoskeleton.Q34647845
Remodelling the walls of the nucleusQ34718080
Apoptosis and nucleosomesQ35045866
Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.Q36572588
Partial cleavage of A-type lamins concurs with their total disintegration from the nuclear lamina during apoptosisQ39640684
Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenesQ40370592
Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeletonQ40565474
Identification of essential genes in cultured mammalian cells using small interfering RNAs.Q40756849
Nuclear envelope breakdown proceeds by microtubule-induced tearing of the laminaQ40757025
Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivoQ40915136
Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathwayQ42454438
Peripheral nuclear matrix actin forms perinuclear shellsQ42827952
Steroid receptor fusion proteins for conditional activation of Raf-MEK-ERK signaling pathwayQ42829924
Protein kinase C-beta II Is an apoptotic lamin kinase in polyomavirus-transformed, etoposide-treated pyF111 rat fibroblastsQ43921988
Effects of cytochalasin, phalloidin, and pH on the elongation of actin filaments.Q52455490
Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei.Q52507690
PKC-δ is an apoptotic lamin kinaseQ56795988
Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cellsQ57258304
A Presumed Human Nuclear Autoantigen That Translocates to Plasma Membrane Blebs during ApoptosisQ59488435
Blebs and apoptotic bodies are B cell autoantigensQ74334880
Lamin B phosphorylation by protein kinase calpha and proteolysis during apoptosis in human leukemia HL60 cellsQ74424476
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectapoptotic processQ14599311
P304page(s)245-255
P577publication date2005-01-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleActin-myosin-based contraction is responsible for apoptotic nuclear disintegration
P478volume168