Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis

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Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S40478-015-0255-6
P932PMC publication ID4660723
P698PubMed publication ID26610346
P5875ResearchGate publication ID284812995

P50authorStephen B. McMahonQ29653464
Yury BogdanovQ46798919
Franziska DenkQ60325988
P2093author name stringJohn N Wood
Massimo Signore
Mohammed A Nassar
Matt S Ramer
Leanne M Ramer
Erin L K S Erskine
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Peripherin and ATF3 genes are differentially regulated in regenerating and non-regenerating primary sensory neuronsQ30885254
Relative effects of tamoxifen, raloxifene, and conjugated equine estrogens on cognitionQ33841626
Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligandsQ34068091
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Estrogen- and tamoxifen-associated effects on brain structure and functionQ34292194
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Temporal control of gene deletion in sensory ganglia using a tamoxifen-inducible Advillin-Cre-ERT2 recombinase mouse.Q35677778
Lack of cocaine-like discriminative-stimulus effects of σ-receptor agonists in rats.Q36883121
MEK1/2 inhibition suppresses tamoxifen toxicity on CNS glial progenitor cells.Q37179748
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Excitation-transcription coupling in sympathetic neurons and the molecular mechanism of its initiationQ37595161
Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligandsQ37884916
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Is basic research providing answers if adjuvant anti-estrogen treatment of breast cancer can induce cognitive impairment?Q38077049
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Structural similitudes between cytotoxic antiestrogen-binding site (AEBS) ligands and cytotoxic sigma receptor ligands. Evidence for a relationship between cytotoxicity and affinity for AEBS or sigma-2 receptor but not for sigma-1 receptorQ40913236
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Decision-making impairments in breast cancer patients treated with tamoxifenQ42704792
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Cognitive effects of Tamoxifen in pre-menopausal women with breast cancer compared to healthy controlsQ44859258
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Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injuryQ73445277
Dynamic pattern of reg-2 expression in rat sensory neurons after peripheral nerve injuryQ74661395
Tamoxifen associated bilateral optic neuropathyQ87374398
P921main subjecttamoxifenQ412178
P304page(s)74
P577publication date2015-11-26
P1433published inActa Neuropathologica CommunicationsQ27724912
P1476titleTamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis
P478volume3