Induction of a secreted protein by the myxoid liposarcoma oncogene

scientific article

Induction of a secreted protein by the myxoid liposarcoma oncogene is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1999PNAS...96.5025K
P356DOI10.1073/PNAS.96.9.5025
P932PMC publication ID21810
P698PubMed publication ID10220412
P5875ResearchGate publication ID13078836

P50authorDavid RonQ18195722
P2093author name stringX Wang
K J Turner
L J Fitz
Y Yin
K A Jacobs
M Kuroda
P Chung
J Sok
J W Giannotti
P Murtha-Riel
P2860cites workCytogenetic findings in liposarcoma correlate with histopathologic subtypesQ44846709
Versatile retroviral vectors for potential use in gene therapyQ45867146
Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpointsQ60035789
Additional evidence of a variant translocation t(12;22) with EWS/CHOP fusion in myxoid liposarcoma: clinicopathological featuresQ73721197
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumoursQ24298221
Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcomaQ24309359
The EWS gene, involved in Ewing family of tumors, malignant melanoma of soft parts and desmoplastic small round cell tumors, codes for an RNA binding protein with novel regulatory domainsQ24319886
Identification of novel stress-induced genes downstream of chopQ24533261
The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1Q24629399
A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOPQ28240554
Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cellsQ28276215
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP KinaseQ28280649
Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteinsQ28287408
CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcriptionQ28287446
Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUSQ28296815
The CCAAT/enhancer binding protein and its role in adipocyte differentiation: evidence for direct involvement in terminal adipocyte developmentQ28513428
Stress-induced binding of the transcriptional factor CHOP to a novel DNA control elementQ28570085
CHOP-Dependent stress-inducible expression of a novel form of carbonic anhydrase VIQ28587564
Impaired Energy Homeostasis in C/EBPα Knockout MiceQ34662358
Mechanism of strand cleavage and exchange in the Cre-lox site-specific recombination systemQ34692919
Two distinct FUS breakpoint clusters in myxoid liposarcoma and acute myeloid leukemia with the translocations t(12;16) and t(16;21).Q34719993
Translocation t(12;16)(q13;p11) in myxoid liposarcoma and round cell liposarcoma: molecular and cytogenetic analysisQ34722721
Identifying differences in mRNA expression by representational difference analysis of cDNAQ35004368
Transcriptional activation by TAL1 and FUS-CHOP proteins expressed in acute malignancies as a result of chromosomal abnormalities.Q35669591
Oncogenic transformation and inhibition of adipocytic conversion of preadipocytes by TLS/FUS-CHOP type II chimeric proteinQ35763469
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).Q36561426
Regulation of the C/EBP-related gene gadd153 by glucose deprivationQ36694493
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agentsQ36761728
CCAAT-enhancer binding protein: a component of a differentiation switchQ37624411
Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient miceQ37696753
GADD153/CHOP, a DNA damage-inducible protein, reduced CAAT/enhancer binding protein activities and increased apoptosis in 32D c13 myeloid cells.Q38355295
Packaging system for rapid production of murine leukemia virus vectors with variable tropismQ40067097
Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153).Q40789492
Reciprocal regulation of adipogenesis by Myc and C/EBP alphaQ41628463
Alteration of proteoglycan metabolism during the differentiation of 3T3-L1 fibroblasts into adipocytesQ41672410
CHOP (GADD153) and its oncogenic variant, TLS-CHOP, have opposing effects on the induction of G1/S arrest.Q42801637
Gadd45 and Gadd153 messenger RNA levels are increased during hypoxia and after exposure of cells to agents which elevate the levels of the glucose-regulated proteinsQ42818320
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytesQ42820082
Human translocation liposarcoma-CCAAT/enhancer binding protein (C/EBP) homologous protein (TLS-CHOP) oncoprotein prevents adipocyte differentiation by directly interfering with C/EBPbeta functionQ42829035
Regulation of fibronectin, integrin and cytoskeleton expression in differentiating adipocytes: inhibition by extracellular matrix and polylysineQ42834581
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectmyxoid liposarcomaQ6949365
P304page(s)5025-5030
P577publication date1999-04-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleInduction of a secreted protein by the myxoid liposarcoma oncogene
P478volume96

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cites work (P2860)
Q42223420A novel oncogenic pathway by TLS-CHOP involving repression of MDA-7/IL-24 expression
Q34952133Advances in the targeted therapy of liposarcoma
Q30459373Biochemical Properties and Biological Functions of FET Proteins
Q38338293Comparable transforming capacities and differential gene expression patterns of variant FUS/CHOP fusion transcripts derived from soft tissue liposarcomas
Q36272048Detection of fusion genes in sarcomas using paraffin-embedded tissues
Q36332766Human synovial lubricin expresses sialyl Lewis x determinant and has L-selectin ligand activity
Q34662602Male sterility and enhanced radiation sensitivity in TLS(-/-) mice
Q37248204Organization of nuclear architecture during adipocyte differentiation
Q35746797PLAG1 alterations in lipoblastoma: involvement in varied mesenchymal cell types and evidence for alternative oncogenic mechanisms
Q28574873Serial analysis of gene expression in the rat striatum following methamphetamine administration
Q51842639TLS-CHOP target gene DOL54 expression in liposarcomas and malignant fibrous histiocytomas.
Q33999337The TET family of proteins: functions and roles in disease
Q34566943The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma cells
Q51372405Ultraviolet light (UVB and UVA) induces the damage-responsive transcription factor CHOP/gadd153 in murine and human epidermis: evidence for a mechanism specific to intact skin.

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