Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death

scientific article

Diabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1089/ARS.2005.7.1581
P698PubMed publication ID16356121

P2093author name stringRenu A Kowluru
P2860cites workOxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitrationQ42472180
P433issue11-12
P921main subjectdiabetic retinopathyQ631361
cell deathQ2383867
P304page(s)1581-1587
P577publication date2005-11-01
P1433published inAntioxidants & Redox SignalingQ4775078
P1476titleDiabetic retinopathy: mitochondrial dysfunction and retinal capillary cell death
P478volume7

Reverse relations

cites work (P2860)
Q92599989A review of the putative causal mechanisms associated with lower macular pigment in diabetes mellitus
Q38909591AGEs Promote Oxidative Stress and Induce Apoptosis in Retinal Pigmented Epithelium Cells RAGE-dependently
Q35404674Abrogation of MMP-9 gene protects against the development of retinopathy in diabetic mice by preventing mitochondrial damage.
Q88613149Acute Effect of Low-Dose Space Radiation on Mouse Retina and Retinal Endothelial Cells
Q39129556Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells
Q36736338Alpha-lipoic acid: physiologic mechanisms and indications for the treatment of metabolic syndrome
Q33679152Apoptosis in Diabetic Fibrovascular Membranes After Panretinal Photocoagulation
Q64054648Application of a Flow-Based Hollow-Fiber Co-Culture System to Study Cellular Influences under Hyperglycemic Conditions
Q38941639Application of multiplex immunoassay technology to investigations of ocular disease
Q47095933Astragaloside IV protects rat retinal capillary endothelial cells against high glucose-induced oxidative injury
Q64276093Astragalus polysaccharides suppresses high glucose-induced metabolic memory in retinal pigment epithelial cells through inhibiting mitochondrial dysfunction-induced apoptosis by regulating miR-195
Q33748559BASP1 promotes apoptosis in diabetic nephropathy.
Q35591570Beyond AREDS: is there a place for antioxidant therapy in the prevention/treatment of eye disease?
Q44442577Blood-Brain Barrier Disruption and Neurovascular Unit Dysfunction in Diabetic Mice: Protection with the Mitochondrial Carbonic Anhydrase Inhibitor Topiramate
Q39365499Connexin channel and its role in diabetic retinopathy
Q55124014Correlation of biomarkers thiobarbituric acid reactive substance, nitric oxide and central subfield and cube average thickness in diabetic retinopathy: a cross-sectional study.
Q35687928Diabetic retinopathy and damage to mitochondrial structure and transport machinery
Q46337031Diabetic retinopathy, metabolic memory and epigenetic modifications
Q35545811Diabetic retinopathy, superoxide damage and antioxidants.
Q37733102Dietary hyperglycemia, glycemic index and metabolic retinal diseases
Q33729972Differential expression and role of hyperglycemia induced oxidative stress in epigenetic regulation of β1, β2 and β3-adrenergic receptors in retinal endothelial cells
Q37479451Dopamine deficiency contributes to early visual dysfunction in a rodent model of type 1 diabetes
Q36101886Downregulating p22phox ameliorates inflammatory response in Angiotensin II-induced oxidative stress by regulating MAPK and NF-κB pathways in ARPE-19 cells
Q36292177Downregulation of mitochondrial connexin 43 by high glucose triggers mitochondrial shape change and cytochrome C release in retinal endothelial cells
Q27690757ER stress and apoptosis: a new mechanism for retinal cell death
Q42183977Effects of antioxidant gene therapy on the development of diabetic retinopathy and the metabolic memory phenomenon
Q26775552Epidemiology of diabetic retinopathy, diabetic macular edema and related vision loss
Q90221699Epigenetic Modifications Compromise Mitochondrial DNA Quality Control in the Development of Diabetic Retinopathy
Q92221968Epigenetic Modifications in Peripheral Blood as Potential Noninvasive Biomarker of Diabetic Retinopathy
Q92093237Epigenetics and Mitochondrial Stability in the Metabolic Memory Phenomenon Associated with Continued Progression of Diabetic Retinopathy
Q42854405Evaluation of the impact of diabetes on retinal metabolites by NMR spectroscopy.
Q38705664From blood-brain barrier to blood-brain interface: new opportunities for CNS drug delivery
Q90568146Ginsenoside Rb1 Attenuates High Glucose-Induced Oxidative Injury via the NAD-PARP-SIRT Axis in Rat Retinal Capillary Endothelial Cells
Q41990280Glycosylation End-product Formation in Retinal Membranes, an Energy Alteration Injury
Q28578531HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II
Q31083347Heme oxygenase-1 protects retinal endothelial cells against high glucose- and oxidative/nitrosative stress-induced toxicity
Q33769436High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy
Q36301307High Glucose-induced Retinal Pericyte Apoptosis Depends on Association of GAPDH and Siah1.
Q33947328High glucose disrupts mitochondrial morphology in retinal endothelial cells: implications for diabetic retinopathy
Q35591494High glucose induces mitochondrial morphology and metabolic changes in retinal pericytes
Q46768236High sugar-induced repression of antioxidant and anti-apoptotic genes in lens: reversal by pyruvate
Q35891564High-mobility group box 1 protein is implicated in advanced glycation end products-induced vascular endothelial growth factor A production in the rat retinal ganglion cell line RGC-5.
Q52753708Homonoia riparia and its major component, myricitrin, inhibit high glucose-induced apoptosis of human retinal pericytes.
Q39569586Hyperglycemia induces apoptosis via CB1 activation through the decrease of FAAH 1 in retinal pigment epithelial cells
Q41653304Hyperlipidemia and the development of diabetic retinopathy: Comparison between type 1 and type 2 animal models
Q36355485Hypoxia-induced oxidative stress in ischemic retinopathy
Q38944575Hypoxia-regulated retinal glial cell-specific promoter for potential gene therapy in disease
Q33306583Imaging mitochondria in living corneal endothelial cells using autofluorescence microscopy
Q37159434Increased oxidative stress in diabetes regulates activation of a small molecular weight G-protein, H-Ras, in the retina
Q34538639Influence of retinopathy on the achromatic and chromatic vision of patients with type 2 diabetes
Q35928454Interleukin-1β and mitochondria damage, and the development of diabetic retinopathy
Q90334233Interplay between BMPs and Reactive Oxygen Species in Cell Signaling and Pathology
Q37396370Interrelationship between activation of matrix metalloproteinases and mitochondrial dysfunction in the development of diabetic retinopathy
Q38116121Lipoic acid in animal models and clinical use in diabetic retinopathy
Q34077433Matrix metalloproteinase-2 in the development of diabetic retinopathy and mitochondrial dysfunction
Q43442147Mechanisms of modified LDL-induced pericyte loss and retinal injury in diabetic retinopathy
Q32186021Mesenchymal stem cells attenuate hydrogen peroxide-induced oxidative stress and enhance neuroprotective effects in retinal ganglion cells
Q34492507Metabolic memory in diabetes - from in vitro oddity to in vivo problem: role of apoptosis
Q55474609MicroRNA-27a protects retinal pigment epithelial cells under high glucose conditions by targeting TLR4.
Q26822476Microvascular complications and diabetic retinopathy: recent advances and future implications
Q35457777Mitochondrial biogenesis and the development of diabetic retinopathy
Q33668501Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities
Q34221905Mitochondrial dysfunction in retinal diseases
Q28383025Mitochondrial function in vascular endothelial cell in diabetes
Q33867982Modulation of diabetic retinopathy pathophysiology by natural medicines through PPAR-γ-related pharmacology.
Q51734430Mutational Analysis of the Mitochondrial DNA Displacement-Loop Region in Human Retinoblastoma with Patient Outcome.
Q61800528Neuroprotective effects of PPARα in retinopathy of type 1 diabetes
Q46248925Notoginsenoside R1 attenuates high glucose-induced endothelial damage in rat retinal capillary endothelial cells by modulating the intracellular redox state
Q89685080Novel Detection and Restorative Levodopa Treatment for Pre-Clinical Diabetic Retinopathy
Q35027703Novel role of mitochondrial matrix metalloproteinase-2 in the development of diabetic retinopathy
Q35049903Ocular complications of diabetes mellitus
Q39390584Osmotic expression of aldose reductase in retinal pigment epithelial cells: involvement of NFAT5.
Q34512906Oxidative damage of mitochondrial DNA in diabetes and its protection by manganese superoxide dismutase
Q35819297Oxidative stress and diabetic retinopathy
Q37226580Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives
Q38480783Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy.
Q34314724Peroxynitrite-driven mechanisms in diabetes and insulin resistance - the latest advances
Q64058295Perturbed Biochemical Pathways and Associated Oxidative Stress Lead to Vascular Dysfunctions in Diabetic Retinopathy
Q38888617Protective Effects of Panax notoginseng Saponins against High Glucose-Induced Oxidative Injury in Rat Retinal Capillary Endothelial Cells.
Q36521057Protective effects of lipoic acid on chrysene-induced toxicity on Müller cells in vitro.
Q36557787Proteomic modification by nitric oxide
Q42514020R-(+)-alpha-lipoic acid inhibits endothelial cell apoptosis and proliferation: involvement of Akt and retinoblastoma protein/E2F-1.
Q35619430Rapid, noninvasive detection of diabetes-induced retinal metabolic stress
Q59279106Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes
Q37081874Redox compartmentalization in eukaryotic cells
Q35903992Reversal of the Caspase-Dependent Apoptotic Cytotoxicity Pathway by Taurine from Lycium barbarum (Goji Berry) in Human Retinal Pigment Epithelial Cells: Potential Benefit in Diabetic Retinopathy
Q34009114Role of histone acetylation in the development of diabetic retinopathy and the metabolic memory phenomenon
Q36468930Role of matrix metalloproteinase-2 and -9 in the development of diabetic retinopathy
Q40958087Silencing of insulin receptor substrate-1 increases cell death in retinal Müller cells.
Q42915712Simvastatin suppresses expression of angiogenic factors in the retinas of rats with streptozotocin-induced diabetes
Q46929681TIAM1-RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy.
Q91795713Targeting Altered Mitochondrial Biogenesis in the Brain of Diabetic Rats: Potential Effect of Pioglitazone and Exendin-4
Q52643215Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from high glucose-induced apoptosis.
Q58762667The Oxidative Stress and Mitochondrial Dysfunction during the Pathogenesis of Diabetic Retinopathy
Q91656284The Regulatory Role of Rac1, a Small Molecular Weight GTPase, in the Development of Diabetic Retinopathy
Q49463670The Role of Mitochondrial DNA (mtDNA) in the Development of Diabetic Retinopathy (DR): A Systematic Review
Q37786972The importance of mitochondria in age-related and inherited eye disorders.
Q31146840Therapeutic implications of curcumin in the prevention of diabetic retinopathy via modulation of anti-oxidant activity and genetic pathways
Q35618941Tiam1-Rac1 Axis Promotes Activation of p38 MAP Kinase in the Development of Diabetic Retinopathy: Evidence for a Requisite Role for Protein Palmitoylation
Q88170813Time-lapse microscopy of oxidative stress demonstrates metabolic sensitivity of retinal pericytes under high glucose condition
Q27028225Vitreous mediators in retinal hypoxic diseases

Search more.